Target Localization Accuracy of Image Registrations in Cone Beam Computed Tomography-Guided Stereotactic Body Radiation Therapy for Lung Cancer [0.03%]
锥形束CT引导的立体定向体放射治疗中肺癌图像配准的目标定位精度研究
Seong Soon Jang,Na-Young An,Hee Kyung Kim et al.
Seong Soon Jang et al.
Background: To evaluate the target localization accuracy of image registration methods in cone beam computed tomography (CBCT)-based image guidance (IG) for lung stereotactic body radiation therapy (SBRT) and the associat...
A Comprehensive Study on Clinical Outcomes and Safety of Neoadjuvant Immunotherapy Combined With Chemotherapy in Limited-Stage Small Cell Lung Cancer [0.03%]
广泛期小细胞肺癌患者免疫治疗联合化疗新辅助治疗的临床疗效及安全性综合评估研究
Fan Ge,Guo Lin,Zhenyu Huo et al.
Fan Ge et al.
Background: This study aims to explore clinical outcomes and safety of neoadjuvant immunotherapy combined with chemotherapy in limited-stage small cell lung cancer (SCLC), providing insights for upcoming clinical trials. ...
Meta-Analysis
Thoracic cancer. 2025 Aug;16(15):e70125. DOI:10.1111/1759-7714.70125 2025
Efficacy and Safety of Afatinib Plus Bevacizumab as First-Line Treatment for Advanced NSCLC Patients With Epidermal Growth Factor Receptor (EGFR) Mutations: A Multicenter, Phase II Trial [0.03%]
阿法替尼联合贝伐珠单抗一线治疗表皮生长因子受体（EGFR）突变的晚期NSCLC患者疗效和安全性研究：一项多中心Ⅱ期临床试验
Huiyang Shi,Miaohan Wang,Junling Li et al.
Huiyang Shi et al.
Background: Studies indicated that afatinib combined with angiogenesis inhibitor may achieve promising efficacy in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. ...
Clinical Trial
Thoracic cancer. 2025 Aug;16(15):e70137. DOI:10.1111/1759-7714.70137 2025
Sortilin-1, Targeted by miR-146a, Regulates the Behavior of Non-Small Cell Lung Cancer [0.03%]
靶向miR-146a的分拣蛋白1（SORT1）调控非小细胞肺癌行为的研究
Xi Lin,Zhi Yan,Ling Hai et al.
Xi Lin et al.
Background: Sortilin-1 (SORT1) has been implicated in the pathogenesis of various malignancies, but its role in non-small cell lung cancer (NSCLC) remains to be elucidated. ...
Feasibility, Safety, and Early Outcomes of Image-Guided Segmentectomy Using Near-Infrared Fluorescence Dye for Tumor Visualization and Margin Identification: A Collaborative Effort by the Surgical and Radiological Teams [0.03%]
基于影像导航的近红外荧光显影剂在解剖性段切除术中定位肿瘤及识别切缘的可行性、安全性和近期疗效：外科和放射科团队的协作研究
Ching Feng Wu,Kuei An Chen,Ming Ju Hsieh et al.
Ching Feng Wu et al.
Introduction: Despite advances in lung cancer management, it remains the leading cause of cancer-related deaths. Low-dose computed tomography (LDCT) screening has increased detection of small, difficult-to-palpate lung le...
Correction to "Impact of Exposure to Benzodiazepines on Adverse Effects and Efficacy of PD-1/PD-L1 Blockade in Patients With Non-Small Cell Lung Cancer" [0.03%]
对“苯二氮卓类药物暴露对非小细胞肺癌患者PD-1/PD-L1阻断的不良反应和疗效的影响”的勘误通知
Published Erratum
Thoracic cancer. 2025 Aug;16(15):e70143. DOI:10.1111/1759-7714.70143 2025
Integrating Single-Cell Transcriptomics and Machine Learning to Define an ac4C Gene Signature in Lung Adenocarcinoma [0.03%]
单细胞转录组和机器学习整合定义肺腺癌ac4C基因签名
Yuan Wang,Wei Su,Guangyao Zhou et al.
Yuan Wang et al.
Introduction: Lung adenocarcinoma, the most common subtype of non-small cell lung cancer, faces challenges such as drug resistance and tumor heterogeneity. N4-acetylcytidine (ac4C) is an important RNA modification involve...
Pretreatment CT Texture Analysis for Predicting Survival Outcomes in Advanced Nonsmall Cell Lung Cancer Patients Receiving Immunotherapy: A Systematic Review and Meta-Analysis [0.03%]
基于免疫治疗的晚期非小细胞肺癌患者预后预测的影像组学纹理分析：系统评价和Meta分析
Yao-Ren Zhang,Yueh-Hsun Lu,Che-Ming Lin et al.
Yao-Ren Zhang et al.
Background: While established biomarkers predict immunotherapy response in advanced nonsmall cell lung cancer (NSCLC), additional noninvasive imaging biomarkers may enhance treatment selection. Pretreatment computed tomog...
Meta-Analysis
Thoracic cancer. 2025 Aug;16(15):e70144. DOI:10.1111/1759-7714.70144 2025
Lung Adenocarcinoma Expressing an EML4-ALK Fusion Transcript With Premature Stop Codons and Response to Alectinib: A Case Report [0.03%]
携带早辍密码子EML4-ALK融合转录本的肺腺癌对阿来替尼有反应的一个病例报告
Mami Ozaki,Hiroaki Ikushima,Masaki Suzuki et al.
Mami Ozaki et al.
ALK fusions are well-established oncogenic drivers in lung cancer, typically resulting in ALK activation through dimerization mediated by partner proteins. However, alternative mechanisms of ALK activation have also been reported. We herein...
Case Reports
Thoracic cancer. 2025 Aug;16(15):e70146. DOI:10.1111/1759-7714.70146 2025
The Association Between Thromboembolic Events and ALK, ROS1, RET Rearrangements or EGFR Mutations in Patients With Advanced Lung Adenocarcinoma: A Retrospective Cohort Study [0.03%]
关于晚期肺腺癌患者血栓事件与ALK、ROS1、RET重排或EGFR突变关联的队列研究
Xiaohan Qian,Mengjiao Fu,Jing Zheng et al.
Xiaohan Qian et al.
Introduction: Previous studies have reported inconsistent findings regarding the associationbetween ALK and ROS1 rearrangements in lung cancer and thromboembolic risk. This retrospective study aimed to investigate this as...