Efficacy and safety data of belimumab in patients with systemic lupus erythematosus [0.03%]
贝利木单抗治疗系统性红斑狼疮患者的疗效和安全性数据
Bita Shakoory,Winn Clatham
Bita Shakoory
Belimumab is a human genome derived monoclonal antibody with specificity for BLyS (B lymphocyte stimulator, or B-cell activating factor [BAFF]), a cytokine that promotes the survival and maturation of B cells into antibody-secreting plasmab...
Jürgen Braun
Jürgen Braun
Methotrexate (MTX) is currently the most frequently used drugs in the treatment of rheumatoid arthritis (RA). The drug had been synthesized in 1948 and first tests to treat patients with psoriasis and RA were published in 1951. However, unt...
Tocilizumab: a novel humanized anti-interleukin 6 receptor antibody for the treatment of patients with rheumatoid arthritis [0.03%]
托珠单抗:一种新型人源化抗白细胞介素-6受体抗体用于治疗类风湿性关节炎患者
Rieke Alten
Rieke Alten
Tocilizumab (TCZ; RoActemra® or Actemra®) is a recombinant humanized monoclonal antibody that acts as an interleukin 6 (IL-6) receptor antagonist. For rheumatoid arthritis (RA), intravenous (IV) TCZ 8 mg/kg every 4 weeks has been approved...
Stem cell therapy: resetting autoimmunity or postponing the inevitable? [0.03%]
干细胞疗法:根治自身免疫还是延缓不可避免的病情?
Jacob M van Laar
Jacob M van Laar
Pedro Barata,Mariana Cervaens,Rita Resende et al.
Pedro Barata et al.
In the last decade, competitive sports have taken on a whole new meaning, where intensity has increased together with the incidence of injuries to the athletes. Therefore, there is a strong need to develop better and faster treatments that ...
Sternocostoclavicular hyperostosis: a review [0.03%]
sternocostoclavicular hypertrophy syndrome(SCCH)文献复习
Matthew B Carroll
Matthew B Carroll
Sternocostoclavicular hyperostosis (SCCH) is a chronic inflammatory disorder which presents with erythema, swelling, and pain of the sternoclavicular joint. Approximately one half of patients have acne or pustular lesions with the best desc...
Hans Carlson,Nels Carlson
Hans Carlson
Musculoskeletal pain is a common reason for patients to seek care from healthcare providers. These conditions are predominantly nontraumatic injuries with a broad differential diagnosis and often without a specific diagnosis despite thoroug...
Factors that contribute to low bone density in postmenopausal women in different amazonian communities [0.03%]
影响不同亚马逊地区绝经后妇女低骨密度的因素
Cláudio Joaquim Borba-Pinheiro,Alexandre Janotta Drigo,Mauro César Gurgel de Alencar Carvalho et al.
Cláudio Joaquim Borba-Pinheiro et al.
Background: The aim of this study was to verify socioeconomic differences, nutrition, body balance and quality of life (QoL) in postmenopausal women with low bone mineral density (BMD) in two Amazonian communities. ...
Evidence of sustained vertebral and nonvertebral antifracture efficacy with ibandronate therapy: a systematic review [0.03%]
伊班磷酸钠治疗可显著降低椎体和非椎体骨折发生率的证据:系统综述
Silvano Adami,Luca Idolazzi,Maurizio Rossini
Silvano Adami
Background: The antifracture efficacy of ibandronate at vertebral and nonvertebral sites was assessed. Methods: A literature review of ...
Tanaz A Kermani,Kenneth J Warrington,Shreyasee Amin
Tanaz A Kermani
The vasculitides encompass a rare subset of autoimmune diseases. Reports of the concurrent association of malignancies with some forms of vasculitis raise the possibility that patients with certain types of vasculitis may be at increased ri...