Is there a future for selective estrogen-receptor modulators in osteoporosis? [0.03%]
选择性雌激素受体调节剂在骨质疏松症中的前景如何？
Roberto C Güerri-Fernández,Adolfo Diez-Perez
Roberto C Güerri-Fernández
Neil Martin,Charles K Li,Lucy R Wedderburn
Neil Martin
Juvenile dermatomyositis (JDM) is a rare but complex and potentially life-threatening autoimmune disease of childhood, primarily affecting proximal muscles and skin. Although the cause of JDM remains unknown it is clear that genetic and env...
Treatment of rheumatoid arthritis in patients with concomitant chronic hepatitis C infection [0.03%]
合并慢性丙型肝炎感染的类风湿关节炎患者的治疗
Amy M Joseph
Amy M Joseph
Hepatitis C virus (HCV) infection is present in 1.8% of the general US population and its prevalence worldwide is estimated at 2-3%. HCV infected patients with concomitant rheumatoid arthritis (RA) pose a particular challenge to the rheumat...
Bazedoxifene: the evolving role of third-generation selective estrogen-receptor modulators in the management of postmenopausal osteoporosis [0.03%]
贝扎洛昔芬在绝经后骨质疏松症治疗中第三代选择性雌激素受体调节剂的作用及展望
Barry S Komm,Arkadi A Chines
Barry S Komm
Osteoporosis is a significant public health concern, particularly for postmenopausal women. Current treatment options may not be appropriate for all women. Selective estrogen-receptor modulators (SERMs) are a class of molecules with tissue-...
Efficacy of vitamin E in knee osteoarthritis management of North Indian geriatric population [0.03%]
维生素E对北印度老年人群膝关节骨关节炎管理的有效性
Ijen Bhattacharya,Rahul Saxena,Veena Gupta
Ijen Bhattacharya
Background: Osteoarthritis (OA) is the most common cause of chronic pain and disability in the elderly. It involves progressive destruction of articular cartilage as a consequence of various factors including augmented ox...
Preference, satisfaction and usability of subcutaneously administered methotrexate for rheumatoid arthritis or psoriatic arthritis: results of a postmarketing surveillance study with a high-concentration formulation [0.03%]
皮下注射甲氨蝶呤治疗类风湿关节炎或银屑病关节炎的偏好、疗效和使用便利性：高浓度制剂上市后监测研究结果
Frank Striesow,Andreas Brandt
Frank Striesow
Background/objectives: This postmarketing surveillance study assessed the preference, satisfaction, usability, and tolerability of subcutaneous self-administration of a high-concentration (50 mg/ml) ready-to-use formulati...
David J Gazeley,Mary E Cronin
David J Gazeley
The idiopathic inflammatory myopathies (IIMs) are rare disorders with the unifying feature of proximal muscle weakness. These diseases include polymyositis(PM), dermatomyositis (DM) and inclusion body myositis (IBM) as the most common. The ...
Atypical femur fractures: a review of the evidence and its implication to clinical practice [0.03%]
非典型股骨骨折：文献证据及其临床意义回顾
Christian M Girgis,Markus J Seibel
Christian M Girgis
Whilst bisphosphonates are an established modality in the treatment of osteoporosis, there have been increasing concerns regarding the risk of an unusual form of femur fracture amongst patients receiving bisphosphonates for prolonged period...
Amy J Lanou
Amy J Lanou
Numerous studies have investigated the relationship between soy foods, soy protein, or isoflavone extracts and markers of bone health and osteoporosis prevention, and have come to conflicting conclusions. Research on dietary patterns, rathe...
Shouma Dutta,Yasmeen Ahmad
Shouma Dutta
The crucial role of T cells in the pathogenesis of rheumatoid arthritis (RA) is well recognized. Tacrolimus is an immunomodulator that acts by the inhibition of T-cell activation. There have been numerous studies examining the use of tacrol...