Fine Mapping without Phenotyping: Identification of Selection Targets in Secondary Evolve and Resequence Experiments [0.03%]
无需表型鉴定的精细定位：在二次进化和重测序实验中识别选择目标
Anna Maria Langmüller,Marlies Dolezal,Christian Schlötterer
Anna Maria Langmüller
Evolve and Resequence (E&R) studies investigate the genomic selection response of populations in an Experimental Evolution setup. Despite the popularity of E&R, empirical studies in sexually reproducing organisms typically suffer from an ex...
Reconstructing the History of Variation in Effective Population Size along Phylogenies [0.03%]
沿系统发育树重建有效种群大小变异的历史
Mathieu Brevet,Nicolas Lartillot
Mathieu Brevet
The nearly neutral theory predicts specific relations between effective population size (Ne) and patterns of divergence and polymorphism, which depend on the shape of the distribution of fitness effects (DFE) of new mutations. However, test...
Evolution of Recombination Landscapes in Diverging Populations of Bread Wheat [0.03%]
分化的小麦群体中的重组景观的演变
Alice Danguy des Déserts,Sophie Bouchet,Pierre Sourdille et al.
Alice Danguy des Déserts et al.
Reciprocal exchanges of DNA (crossovers) that occur during meiosis are mandatory to ensure the production of fertile gametes in sexually reproducing species. They also contribute to shuffle parental alleles into new combinations thereby fue...
The Chromosome-Level Genome of Triplophysa dalaica (Cypriniformes: Cobitidae) Provides Insights into Its Survival in Extremely Alkaline Environment [0.03%]
大理光唇鱼（裂腹鱼亚科）的染色体水平基因组为极端碱性环境下的生存适应提供了新见解
Chuanjiang Zhou,Bo Hu,Yongtao Tang et al.
Chuanjiang Zhou et al.
Lake Dali Nur, located in Inner Mongolia, North China, is alkaline, with Triplophysa dalaica one of the three fish species that not only survive, but thrive, in the lake. To investigate the presence of molecular mutations potentially respon...
Unexpected Discovery of Hypermutator Phenotype Sounds the Alarm for Quality Control Strains [0.03%]
意外发现超突变体表型敲响培养质量控制菌株警钟
Kun Wu,Zhou-Hua Cheng,Emily Williams et al.
Kun Wu et al.
Microbial strains with high genomic stability are particularly sought after for testing the quality of commercial microbiological products, such as biological media and antibiotics. Yet, using mutation-accumulation experiments and de novo a...
Hunting for Beneficial Mutations: Conditioning on SIFT Scores When Estimating the Distribution of Fitness Effect of New Mutations [0.03%]
寻找有益突变：在估算新突变的表型效应分布时考虑SIFT评分条件
Jun Chen,Thomas Bataillon,Sylvain Glémin et al.
Jun Chen et al.
The distribution of fitness effects (DFE) of new mutations is a key parameter of molecular evolution. The DFE can in principle be estimated by comparing the site frequency spectra (SFS) of putatively neutral and functional polymorphisms. Un...
The Evolution of the Cytochrome c6 Family of Photosynthetic Electron Transfer Proteins [0.03%]
光合电子转移蛋白家族的细胞色素c6的进化
Barnaby Slater,Darius Kosmützky,R Ellen R Nisbet et al.
Barnaby Slater et al.
During photosynthesis, electrons are transferred between the cytochrome b6f complex and photosystem I. This is carried out by the protein plastocyanin in plant chloroplasts, or by either plastocyanin or cytochrome c6 in many cyanobacteria a...
Chromosome-Scale Genome Assembly of the Resurrection Plant Acanthochlamys bracteata (Velloziaceae) [0.03%]
星楼草（Velloziaceae）染色体规模的基因组组装
Zhi-Yuan Gao,Zhang-Hai Li,Dong-Liang Lin et al.
Zhi-Yuan Gao et al.
Acanthochlamys bracteata (Velloziaceae) is a resurrection plant with cold tolerance. Herein, a chromosome-level reference genome of A. bracteata based on Nanopore, Illumina, and Hi-C data is reported. The high-quality assembled genome was 1...
BLAST from the Past: Impacts of Evolving Approaches on Studies of Evolution by Gene Duplication [0.03%]
一脉相“基因”扬帆起航：回顾与展望基因复制在进化研究中的影响及应用
Frédéric J J Chain,Raquel Assis
Frédéric J J Chain
In 1970, Susumu Ohno hypothesized that gene duplication was a major reservoir of adaptive innovation. However, it was not until over two decades later that DNA sequencing studies uncovered the ubiquity of gene duplication across all domains...