Allelic variation at tRNA genes in three nematode species indicates mutation load despite strong purifying selection [0.03%]
线虫三种基因的tRNA基因单体型多态性表明突变负担的存在尽管有强烈的纯化选择作用
Avery Davis Bell,Corinne Simonti,Hector Baños et al.
Avery Davis Bell et al.
Cytosolic transfer RNAs, which are encoded as hundreds of genes in nuclear genomes, experience exceptionally high mutation rates and have been hypothesized to confer substantial mutational load in natural populations. Although this phenomen...
Genome evolution and the enigmatic axial skeleton of the hero shew (Soricidae: Scutisorex somereni) [0.03%]
染色体进化与英雄鼩（齿突鼠科）奇异的轴性骨骼结构
Austin S Chipps,Carl R Hutter,Terrence C Demos et al.
Austin S Chipps et al.
Linking genetic variation with traits of interest has been a longstanding challenge for evolutionary biologists. Here, we explore elements of genome evolution in the hero shrew (Soricidae: Scutisorex somereni): a small, elusive mammal with ...
Genomic characterization of dengue virus in the Ningxia Hui Autonomous Region, China (2019 and 2023) [0.03%]
中国宁夏回族自治区登革病毒的基因组特征（2019年和2023年）
Longshan Li,Jun Zhan,Dongzhi Yang et al.
Longshan Li et al.
Dengue virus (DENV) transmission has risen across China in recent years, but genomic data from inland regions remain scarce. We screened nine clinical samples collected in Ningxia in 2019 and 2023, obtaining five near-complete DENV-1 genome...
Genome assembly of Spinifex sericeus provides insights into repetitive content and haplotype variation in a dioecious coastal grass [0.03%]
穗羽茅基因组组装揭示了一种雌雄异体海滨草本植物的重复序列和单倍型变异
Stephanie H Chen,Jason G Bragg,Ashley Jones
Stephanie H Chen
Spinifex sericeus (beach spinifex) is a perennial, dioecious grass native to coastal ecosystem of Oceania that has an important role in dune stability. We present a near telomere-to-telomere, haplotype-resolved nuclear genome and complete o...
Genomes from 117 vertebrate species reveal rapidly evolving segmental-duplication landscapes [0.03%]
来自117种脊椎动物的基因组揭示了快速进化的节段重复景观
Alber Aqil,Saiful Islam,Faraz Hach et al.
Alber Aqil et al.
Segmental duplications are major drivers of evolutionary innovation, yet their dynamics across vertebrates remain poorly understood. Here, we identify segmental duplications from long-read-sequenced genomes of 117 vertebrates and one starfi...
Assessing the potential of ancient protein sequences in the study of hominid evolution [0.03%]
古蛋白质序列在人类起源研究中的潜力评估
Ioannis Patramanis,Laurits Skov,Enrico Cappellini et al.
Ioannis Patramanis et al.
Palaeoproteomic data can provide invaluable insights into hominid evolution over long timescales. Yet, the potential and limitations of ancient protein sequences to resolve evolutionary relations between species remains largely unexplored. ...
Substitution spectrum and selection at G-quadruplexes in great ape telomere-to-telomere genomes [0.03%]
类人猿端到端基因组中的G-四链体替代光谱和选择
Xinru Zhang,Saswat Mohanty,Francesca Chiaromonte et al.
Xinru Zhang et al.
G-quadruplexes (G4s) are noncanonical DNA secondary structures formed by runs of guanines (stems) connected by other nucleotides (loops). These structures are enriched at regulatory regions such as promoters, CpG islands, untranslated regio...
Brett N Adey,Danielle J Maddock,Sylvie Hermann-Le Denmat et al.
Brett N Adey et al.
Large genomes such as the human genome are pervasively transcribed yet encode relatively few unambiguously functional elements. This has led to debate over whether pervasive transcription is indicative of large suites of uncharacterized fun...
Bert Foquet,Lauren E Eccles,Amanda Markee et al.
Bert Foquet et al.
Gene duplications are a major driver of molecular diversification and phenotypic evolution. Arthropod silk genes provide an excellent model for studying these processes due to their extensive internal repeats and rapid evolutionary rates. I...
A chromosome-level assembly and functional genomic resources for the model annelid Capitella teleta [0.03%]
Capitella teleta 模型环节动物染色体水平基因组及功能基因组资源
Billie E Davies,Paul Gonzalez,Abhinav Sur et al.
Billie E Davies et al.
The polychaete Capitella teleta is a primary model for evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology. Although it was the first polychaete genome sequenced, the original assembly is outdated by mo...