Dynamics of Expression Variability Contribute to Retention of Small-Scale vs. Whole-Genome Duplicates [0.03%]
表达可变性动力学有助于保留小规模重复与全基因组重复
Haoran Cai,David L Des Marais
Haoran Cai
Genome analyses reveal that gene duplication in eukaryotes is pervasive, providing a primary source for the emergence of new genes. Nevertheless, the mechanisms influencing the probability of early duplicate retention and the emergence of f...
De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction [0.03%]
濒危植物小米花素豆的从头染色体水平基因组组装及其在保护和可持续提取花素豆碱中的应用
Mariane Brom Sobreiro,Leandro Magalhães,Leandro Araújo Argolo et al.
Mariane Brom Sobreiro et al.
Pilocarpus microphyllus (jaborandi) is an endangered plant species with significant bioeconomic relevance, as it is the main known source of pilocarpine, an alkaloid widely used in the treatment of glaucoma and other diseases. Here, we pres...
Structural Constraints Acting on the SARS-CoV-2 Spike Protein Reveal Limited Space for Viral Adaptation [0.03%]
SARS-CoV-2刺突蛋白结构限制表明病毒的适应空间有限
James C Herzig,Michael L Magwira,Simon C Lovell
James C Herzig
The SARS-CoV-2 pandemic resulted in an unprecedented scientific response. The scale of global genome sequencing, protein structural determination, and targeted studies of variant dynamics has resulted in a unique dataset, providing a valuab...
Genome sequence data reveal complex and variable ploidy in the amoebozoan Acanthamoeba castellanii [0.03%]
基因组序列揭示了变形虫Acanthamoeba castellanii复杂的且可变的染色体倍性状态
Morgan J Colp,John M Archibald
Morgan J Colp
Acanthamoeba castellanii is a free-living amoeba that is emerging as a model organism for the study of eukaryotic microbiology. This species is one of the most widely studied members of the Amoebozoa and is both an important grazer in soil ...
Signatures of Innovation and Selection in the Extremotolerant Yeast Kluyveromyces marxianus [0.03%]
耐极端环境酵母马克斯克鲁维酵母的创新和选择标志
Kaylee E Christensen,Aniliese Deal,Jun-Ting Johnson Wang et al.
Kaylee E Christensen et al.
Organisms specialized to extreme environments can be the product of millions of years of evolutionary engineering and refinement. The underlying genetics can be quite distinct from those operating at earlier stages of trait innovation. In t...
Evolutionary Dynamics of Gene Expression During Thermal Adaptation in Drosophila subobscura [0.03%]
果蝇Drosophila subobscura热适应过程中的基因表达进化动态学研究
Marta A Antunes,Marta A Santos,Mauro Santos et al.
Marta A Antunes et al.
Global warming poses significant challenges to the persistence of biodiversity, requiring a deeper understanding of thermal adaptation, particularly at the genetic level. Examining gene expression changes offers critical insight into the mo...
Petr Fajkus,Barbora Štefanovie,Michal Závodník et al.
Petr Fajkus et al.
The red flour beetle Tribolium castaneum yielded the first resolved telomerase reverse transcriptase structure but lacked a known telomerase RNA. We identify two telomerase RNA paralogs in Tribolium, confirm their expression, and reconstitu...
Identifying Adaptive Footprints in the Presence of Demographic Uncertainty [0.03%]
在人口不确定性情况下识别适应性痕迹
Sandipan Paul Arnab,Mohammad Khan,Andre Luiz Campelo Dos Santos et al.
Sandipan Paul Arnab et al.
Identifying genomic regions shaped by natural selection is a central goal in evolutionary genomics. Existing machine learning methods for this task are typically trained on labeled data simulated according to specific evolutionary scenarios...
Cosmopolitan Gene Families With Known Functions Are Hotspots for the Evolution of Novel Genes in Stony Corals [0.03%]
cosmopolitan已知功能基因家族是石珊瑚新颖基因进化的重要场所
Timothy G Stephens,Arkadiusz W Kulczyk,Debashish Bhattacharya
Timothy G Stephens
Climate change has accelerated research on biodiverse coral reef ecosystems. However, this area of investigation is limited by our understanding of the biology of these organisms, with many of the genes identified as important for stress re...
Regulatory RNA Patterns Associated with Bee Evolution Should Be Interpreted with Caution, but Correlational Studies Should Not Be Entirely Dismissed [0.03%]
关于与蜜蜂进化相关的调控RNA模式应谨慎解读，但相关性研究不应完全否定
Dova Brenman-Suttner,Amro Zayed
Dova Brenman-Suttner
In this response to comments by Heneberg (2026) on our recent review, "The evolution of bees: insights from 'omic studies," we continue the scientific conversation about evidence linking RNA regulatory mechanisms to phenotypic traits. We ac...