Patterns of conservation and loss of Hox genes in xenacoelomorph lineage since divergence from last common bilaterian ancestor [0.03%]
Ariane Buckenmeyer,Samuel Abalde,Joseph F Ryan et al.
Ariane Buckenmeyer et al.
The explosion of body forms found in bilaterians is thought to be tied to the diversification of Hox transcription factors, which play a critical role in development along the anterior-posterior (AP-axis) for most bilaterians. However, the ...
Snakes (Colubridae: Erythrolamprus) with a complex toxic diet show convergent yet highly heterogeneous voltage-gated sodium channel evolution [0.03%]
Valeria Ramírez-Castañeda,Rebecca D Tarvin,Roberto Márquez
Valeria Ramírez-Castañeda
Chemical defense has evolved convergently across multiple lineages and plays a crucial role in shaping ecological communities through selection for toxin resistance. Research on toxin resistance has been pivotal in understanding the genetic...
The use of dN/dS ratios to investigate types of selection in related sexual and asexual lineages [0.03%]
Finn L Klemp,Elvira Hörandl,Mark Maraun et al.
Finn L Klemp et al.
With the increasing availability of whole-genome assemblies, interest in the genomic consequences of diverse reproductive modes has grown. Reduced efficiency of selection in asexually reproducing species is often cited as a major consequenc...
Big Spider, Big Genome: Chromosome-level genome of a North American tarantula (Aphonopelma marxi) and comparative genomics across 300 million years of spider evolution [0.03%]
Ethan J Briggs,Andrea J Noble-Stuen,Chris A Hamilton
Ethan J Briggs
The comparison of chromosome-level genomes allows biologists to investigate new axes of organismal evolution. Spiders comprise a significant proportion of known arachnid diversity, with many complex morphologies and unique natural histories...
Empirical Validation of the Nearly Neutral Theory at Divergence and Population-Genomic Scales Using 144 Placental Mammal Genomes [0.03%]
Mélodie Bastian,David Enard,Nicolas Lartillot
Mélodie Bastian
By limiting the efficacy of selection, random drift is expected to play a major role in genome evolution. Formalizing this idea, the nearly-neutral theory predicts that the ratio of non-synonymous over synonymous polymorphism (πN/πS) with...
Characterization of hairpin loops and cruciforms across 118,019 genomes spanning the tree of life [0.03%]
118,019个生命树基因组中发夹环和十字型结构的特征分析
Nikol Chantzi,Camille Moeckel,Candace S Y Chan et al.
Nikol Chantzi et al.
Inverted repeats (IRs) can form alternative DNA secondary structures, including hairpins and cruciforms, which have a multitude of functional roles and have been associated with genomic instability. However, their prevalence across diverse ...
Complex Patterns of Hitchhiking Mutation Load Among Stickleback Populations [0.03%]
三刺鱼种群中的搭车突变负荷的复杂模式
Jana Nickel,Jan Laine,Andrew D Foote
Jana Nickel
Positive selection causes beneficial alleles to rise to high frequency in a population. This can cause linked genetic variation to "hitchhike," and thereby also rise in frequency. This linked variation may include deleterious recessive alle...
Detecting Positive Selection by Modeling Structure Within Images of Genetic Variation [0.03%]
通过建模遗传变异图像中的结构来检测正向选择
Md Ruhul Amin,Sandipan Paul Arnab,Mohammad Khan et al.
Md Ruhul Amin et al.
A major challenge in population genomics is accurately identifying and characterizing natural selection from genomic data. The wide availability of dense whole-genome datasets has enabled researchers to analyze and localize genetic variatio...
Genetic Footprints of Seasonal Fluctuating Selection: A Comparison With Established Selection Forms [0.03%]
季节性波动选择的遗传痕迹：与既定的选择形式进行比较
Olivia L Johnson,Raymond Tobler,Joshua M Schmidt et al.
Olivia L Johnson et al.
Fluctuating selection is frequently studied in natural populations by observing allele frequency trajectories over evolutionarily brief timeframes or through theoretical analyses of frequency dynamics. However, little is known of its effect...
Evolutionary Complexity of Primate Immune System Uncovered by the Extensive Phylogenomic Sampling [0.03%]
广泛的谱系基因组取样揭示了灵长类动物免疫系统的进化复杂性
Xiuping Zhang,Boyang Wu,Yong Shao
Xiuping Zhang
The immune system mediates the complex interaction between pathogenic microorganisms and their hosts. Despite its significance, the evolutionary mechanisms underlying immune system complexity in primates remain largely elusive. In this stud...