Balancing cholesterol metabolism in the liver and gut: perspectives in health and disease [0.03%]
肝脏和肠道胆固醇代谢的平衡:健康与疾病的视角
Yoshio Yamauchi,Laura J Sharpe,Andrew J Brown
Yoshio Yamauchi
Increasingly, cholesterol is implicated in diseases beyond the cardiovascular system. Major diseases of the gastrointestinal tract and liver are a case in point and are a focus of this Review. Particularly active in whole-body cholesterol m...
Eleni Kotsiliti
Eleni Kotsiliti
Preventive hepatology for MASLD in the MENA region: reframing care from late-stage treatment to early intervention [0.03%]
地中海区域MASLD预防性肝病学:从晚期治疗到早期干预重构护理模式
Mohamed El-Kassas,Zobair M Younossi
Mohamed El-Kassas
Acute-on-chronic liver failure: pathophysiological mechanisms and clinical management [0.03%]
急性加重的慢加急肝衰竭:病理机制与临床处理原则
S K Sarin,Ashok Choudhury,Anupam Kumar et al.
S K Sarin et al.
Acute-on-chronic liver failure (ACLF) is a complex syndrome characterized by acute hepatic decompensation superimposed on pre-existing chronic liver disease or cirrhosis that is associated with acute worsening of portal hypertension, increa...
Author Correction: Μetabolic dysfunction-associated steatotic liver disease: a condition of heterogeneous metabolic risk factors, mechanisms and comorbidities requiring holistic treatment [0.03%]
作者更正:与代谢功能异常相关的肝脂肪变性病是一种异质性的代谢危险因素、机制和合并症的条件,需要全面治疗
Christopher D Byrne,Angelo Armandi,Vanessa Pellegrinelli et al.
Christopher D Byrne et al.
Published Erratum
Nature reviews. Gastroenterology & hepatology. 2026 Jan 3. DOI:10.1038/s41575-025-01169-2 2026
Mucosal glycans: key drivers of the development of inflammatory bowel disease and a potential new therapeutic target [0.03%]
黏膜糖类:炎症性肠病发病的关键驱动因素及潜在新治疗靶点
Salomé S Pinho,Joana Torres,Jean-Frederic Colombel
Salomé S Pinho
Glycans are essential components of homeostatic networks, acting as fine tuners of immunological responses, and are therefore promising targets for manipulating immune tolerance. Glycans shield the entire gut mucosa surface, contributing to...
Potassium-competitive acid blockers for the management of gastroesophageal reflux disease [0.03%]
钾竞争性酸阻滞剂在胃食管反流病管理中的应用
Pierfrancesco Visaggi,Edoardo V Savarino
Pierfrancesco Visaggi
Redefining gastroesophageal junction cancer care with perioperative immunotherapy, minimal residual disease monitoring and new targets [0.03%]
围手术期免疫治疗、微小残留病监测和新靶点定义新的胃食管结合部肿瘤诊治策略
Orla M Fitzpatrick,Yelena Y Janjigian
Orla M Fitzpatrick
Lung-Yi Mak,Daniel Q Huang
Lung-Yi Mak