Nikhil Mayor,Hashim U Ahmed
Nikhil Mayor
Revisiting the dual role of androgens and oestrogens in mammalian sex differentiation with a focus on genitalia [0.03%]
重新审视雄激素和雌激素在哺乳动物性别分化中的双重作用并重点关注生殖器官
Emilie Elmelund,Monica K Draskau,Melanie K Stewart et al.
Emilie Elmelund et al.
Androgen signalling is the primary driver of male sexual differentiation in mammals, directing masculinization during a crucial fetal window. In male fetuses, high levels of fetal androgens, mainly from the testes, promote male reproductive...
Preeti P John,Laura Mike,Indira U Mysorekar et al.
Preeti P John et al.
Bacterial urinary tract infections (UTIs) are prevalent in childhood and adolescence. Paediatric UTIs present unique challenges with respect to diagnosis, prevention and management, and the potential for adverse sequelae. Uropathogenic Esch...
Hai Tong,Li Lin,Mai Zhang et al.
Hai Tong et al.
ADT and activation of HGF and WNT axes in double-null prostate cancer [0.03%]
ADT诱导的HGF和WNT轴活化与前列腺癌骨转移的关系研究
Dexter Hoi Long Leung,Yao Mawulikplimi Adzavon,Gaeul Chu et al.
Dexter Hoi Long Leung et al.
Prostate cancer remains the most frequently diagnosed malignancy in men worldwide. Most primary prostate cancer cells express the androgen receptor (AR) and rely on androgens for oncogenic growth and progression. Thus, androgen deprivation ...
Aalamnoor S Pannu,Jacob Pan,Ethan Layne et al.
Aalamnoor S Pannu et al.
Fathers matter too: sperm-borne epigenetic messages link paternal exposures to next-generation health [0.03%]
父亲也很重要：精子携带的表观遗传信息将父代暴露与子代表型联系起来
Sergio Pecorelli,Roberto Lucchini,Luca Lambertini et al.
Sergio Pecorelli et al.
Management of surgical menopause in female patients with bladder cancer undergoing radical cystectomy [0.03%]
原发性膀胱癌根治术女性患者围手术期卵巢内分泌功能保护及术后管理专家共识(2019年版)
Elizabeth Day,Francesco Pio Bizzarri,Ciara Mackenzie et al.
Elizabeth Day et al.
Radical cystectomy is the gold-standard treatment for patients with muscle-invasive and very high-risk non-muscle-invasive bladder cancer. In female patients, radical cystectomy has traditionally included removal of the uterus, ovaries, fal...
Mehran Dabiri,Dale M Goss,Ranjith Ramasamy et al.
Mehran Dabiri et al.
Sperm DNA fragmentation is a recognized factor in male infertility with direct implications for embryo development, implantation and pregnancy outcomes. Historically, standard semen analysis has not included assessments of DNA integrity, cr...
Long-term adverse effects of modern Wilms tumour therapies: implications for monitoring [0.03%]
儿童肾母细胞瘤现代治疗的远期不良反应：随访监测的应对措施
Filippo Spreafico,Giovanna Gattuso,Marta G Podda et al.
Filippo Spreafico et al.
Wilms tumour is the most common kidney tumour in children. Owing to global collaboration and advances in clinical care, 90% of affected children, including those with metastatic disease, can now be cured. Further improvements in this outsta...