Addressing multiple sclerosis disparities in Latin American and other populations [0.03%]
拉美地区及其他地区人群多发性硬化症差异的应对措施
Heather Wood,Victor Rivera
Heather Wood
Jefferson Becker,Milena Sales Pitombeira,Juan Ignacio Rojas
Jefferson Becker
According to the MS International Federation, the global prevalence of multiple sclerosis (MS) is increasing, although regional variations have been reported, which could provide valuable insights into MS pathophysiology. As we highlight in...
Huntington disease: somatic expansion, pathobiology and therapeutics [0.03%]
亨廷顿病：体细胞性染色体扩张、病理生物学及治疗学
Jasmine Donaldson,Davina Hensman Moss,Marc Ciosi et al.
Jasmine Donaldson et al.
Expansion of simple DNA repeats causes over 45 human, predominantly neurodegenerative, inherited disorders. Huntington disease is a fatal, inherited, neurodegenerative disease caused by a CAG repeat expansion in the huntingtin gene (HTT), r...
Ian Fyfe
Ian Fyfe
Ian Fyfe
Ian Fyfe
Jorge J Llibre-Guerra,Eric M McDade,Suzanne E Schindler et al.
Jorge J Llibre-Guerra et al.
Prevention of Alzheimer disease (AD) is a medical challenge owing to its complex pathogenesis, which involves amyloid-β (Aβ) and tau aggregation, neuroinflammation and progressive neurodegeneration. Development of disease-specific biomark...