Confidence intervals for the between-study variance in random effects meta-analysis using generalised Cochran heterogeneity statistics [0.03%]
使用广义科克伦异质性统计量随机效应荟萃分析中研究间变异的置信区间估算
Dan Jackson
Dan Jackson
Statistical inference is problematic in the common situation in meta-analysis where the random effects model is fitted to just a handful of studies. In particular, the asymptotic theory of maximum likelihood provides a poor approximation, a...
Anne H E Schild,Martin Voracek
Anne H E Schild
Graphs are an essential part of scientific communication. Complex datasets, of which meta-analyses are textbook examples, benefit the most from visualization. Although a number of graph options for meta-analyses exist, the extent to which t...
An empirical comparison of heterogeneity variance estimators in 12 894 meta-analyses [0.03%]
12894项荟萃分析中异质性方差估计量的经验比较
Dean Langan,Julian P T Higgins,Mark Simmonds
Dean Langan
Heterogeneity in meta-analysis is most commonly estimated using a moment-based approach described by DerSimonian and Laird. However, this method has been shown to produce biased estimates. Alternative methods to estimate heterogeneity inclu...
Comparative Study
Research synthesis methods. 2015 Jun;6(2):195-205. DOI:10.1002/jrsm.1140 2015
A scoping review of scoping reviews: advancing the approach and enhancing the consistency [0.03%]
范围审查的范围审查：推进方法和增强一致性
Mai T Pham,Andrijana Rajić,Judy D Greig et al.
Mai T Pham et al.
Background: The scoping review has become an increasingly popular approach for synthesizing research evidence. It is a relatively new approach for which a universal study definition or definitive procedure has not been es...
Exploration of heterogeneity in distributed research network drug safety analyses [0.03%]
分布式研究网络药物安全分析中异质性的探索
Richard A Hansen,Peng Zeng,Patrick Ryan et al.
Richard A Hansen et al.
Distributed data networks representing large diverse populations are an expanding focus of drug safety research. However, interpreting results is difficult when treatment effect estimates vary across datasets (i.e., heterogeneity). In a pre...
Meta-analysis of a continuous outcome combining individual patient data and aggregate data: a method based on simulated individual patient data [0.03%]
结合个体病人数据和综合数据进行连续结果的荟萃分析：基于模拟个体患者数据的方法
Yusuke Yamaguchi,Wataru Sakamoto,Masashi Goto et al.
Yusuke Yamaguchi et al.
When some trials provide individual patient data (IPD) and the others provide only aggregate data (AD), meta-analysis methods for combining IPD and AD are required. We propose a method that reconstructs the missing IPD for AD trials by a Ba...
Michael D deB Edwardes
Michael D deB Edwardes
Conventional meta-analysis estimators are weighted means of study measures, meant to estimate an overall population measure. For measures such as means, mean differences and risk differences, a weighted arithmetic mean is the conventional e...
Thomas A Trikalinos,David C Hoaglin,Kevin M Small et al.
Thomas A Trikalinos et al.
Existing methods for meta-analysis of diagnostic test accuracy focus primarily on a single index test. We propose models for the joint meta-analysis of studies comparing multiple index tests on the same participants in paired designs. These...
A finite mixture method for outlier detection and robustness in meta-analysis [0.03%]
元分析中用于异常值检测和稳健性的有限混合方法
Ken J Beath
Ken J Beath
When performing a meta-analysis unexplained variation above that predicted by within study variation is usually modeled by a random effect. However, in some cases, this is not sufficient to explain all the variation because of outlier or un...
Clinical trial registries are of minimal use for identifying selective outcome and analysis reporting [0.03%]
临床试验注册对识别选择性结果和分析报告的作用很小
Susan L Norris,Haley K Holmer,Rongwei Fu et al.
Susan L Norris et al.
Objective: This study aimed to examine selective outcome reporting (SOR) and selective analysis reporting (SAR) in randomized controlled trials (RCTs) and to explore the usefulness of trial registries for identifying SOR ...