Haruki Koike,Masahisa Katsuno
Haruki Koike
The recent outbreak of Zika virus infection increased the incidence of Guillain-Barré syndrome (GBS). Following the first reported case of GBS after Zika virus infection in 2013, there has been a considerable increase in the incidence of G...
Emiliano Trias,Luis Barbeito,Koji Yamanaka
Emiliano Trias
Accumulating evidence has shown that astrocytes do not just support the function of neurons, but play key roles in maintaining the brain environment in health and disease. Contrary to the traditional understanding of astrocytes as static ce...
Takashi Saito,Takaomi C Saido
Takashi Saito
Alzheimer's disease (AD) is the most common type of neurocognitive disorder. Although both amyloid β peptide deposition and neurofibrillary tangle formation in the AD brain have been established as pathological hallmarks of the disease, ma...
Prevalence and characteristics of transverse myelitis and neuromyelitis optica spectrum disorders in the United Arab Emirates: A multicenter, retrospective study [0.03%]
阿拉伯联合酋长国横贯性脊髓炎和视神经脊髓炎谱系病的流行特征：一项多中心回顾性研究
Kathryn B Holroyd,Faisal Aziz,Miklos Szolics et al.
Kathryn B Holroyd et al.
Objective: To determine the epidemiology and characteristics of transverse myelitis (TM) and neuromyelitis optica spectrum disorders (NMOSD) in Abu Dhabi, United Arab Emirates. ...
Prevalence, treatments and medical cost of multiple sclerosis in Japan based on analysis of a health insurance claims database [0.03%]
基于健康保险理赔数据库的日本多发性硬化患病率、治疗和医疗费用分析
Mieko Ogino,Shuichi Okamoto,Hiroyuki Ohta et al.
Mieko Ogino et al.
Objective: To understand, through an analysis of health insurance claims data, the current treatment status and medical cost of multiple sclerosis (MS) in Japan. ...
Lymphatic system and gut microbiota affect immunopathology of neuroinflammatory diseases, including multiple sclerosis, neuromyelitis optica and Alzheimer's disease [0.03%]
淋巴系统和肠道微生物群影响神经炎症性疾病的免疫病理学，包括多发性硬化症、视神经脊髓炎和阿尔茨海默病
Ikuo Tsunoda
Ikuo Tsunoda
Microbial infections lead to neurological damages either by direct infection in the nervous tissues or by uncontrolled immune responses (immunopathology). For example, in Zika virus infection, microcephaly can be caused by the former, i.e.,...
Helicobacter pylori and gut microbiota in multiple sclerosis versus Alzheimer's disease: 10 pitfalls of microbiome studies [0.03%]
幽门螺杆菌和肠道微生物组在多发性硬化症与阿尔茨海默病中的研究：10个易犯错误之处
Ah-Mee Park,Seiichi Omura,Mitsugu Fujita et al.
Ah-Mee Park et al.
Alteration of microbiota has been associated with intestinal, inflammatory, and neurological diseases. Abundance of "good bacteria" such as Bifidobacterium, or their products have been generally believed to be beneficial for any diseases, w...
Fumihito Yoshii,Yusuke Moriya,Tomohide Ohnuki et al.
Fumihito Yoshii et al.
Fingolimod (FTY) is the first oral medication approved for treatment of relapsing-remitting multiple sclerosis (RRMS). Its effectiveness and safety were confirmed in several phase III clinical trials, but proper evaluation of safety in the ...
Once-daily glatiramer acetate decreases magnetic resonance imaging disease activity in Japanese patients with relapsing-remitting multiple sclerosis [0.03%]
一次注射醋酸格拉替雷能减少日本复发性多发性硬化患者的磁共振成像检测到的病变活动
Takashi Yamamura,Natalia Ashtamker,David Ladkani et al.
Takashi Yamamura et al.
Objective: Multiple sclerosis (MS) prevalence, clinical patterns, and treatment responses vary between races and geographical latitudes. Glatiramer acetate (GA; Copaxone) has provided a safe, effective treatment option fo...
Three immune-mediated disease models induced by Theiler's virus: Multiple sclerosis, seizures and myocarditis [0.03%]
三个由Theiler病毒诱发的自身免疫性疾病模型：多发性硬化、癫痫和心肌炎
Ikuo Tsunoda,Fumitaka Sato,Seiichi Omura et al.
Ikuo Tsunoda et al.
Theiler's murine encephalomyelitis virus (TMEV) infection has been used as a viral model for multiple sclerosis (MS), as TMEV can induce chronic inflammatory demyelinating lesions with viral persistence in the spinal cord of SJL/J mice. In ...