Impact of Tirzepatide Therapy on Thyroid Disease: Understanding Risks and Emerging Insights [0.03%]
tirzepatide治疗对甲状腺疾病的影响：认识风险和新兴见解
Emiliano G Manueli Laos,Bianca Serafica,Andres Fontaine-Nicola et al.
Emiliano G Manueli Laos et al.
The dual GLP-1/GIP agonist tirzepatide is a highly effective anti-obesity therapy. While promising, it is associated with potential adverse effects, including thyroid disease reported in animal models. Due to limited human data, this study ...
Prediction of Cardiovascular Risk Using Machine Learning Based on Maximal Oxygen Consumption, Physical Fitness, and Anthropometry [0.03%]
基于最大摄氧量、身体素质和人体测量的心血管风险预测模型的机器学习方法研究
Rodrigo Yáñez-Sepúlveda,Rodrigo Olivares,Eduardo Guzmán-Muñoz et al.
Rodrigo Yáñez-Sepúlveda et al.
Cardiovascular risk factors in adolescence, often persist into adulthood, with low cardiorespiratory fitness representing one of the strongest predictors of future cardiovascular disease. We aimed to classify cardiovascular risk associated ...
Municipality-Based Lifestyle Intervention of Childhood Overweight and Obesity: 4-Years Follow-Up on BMI Trajectories [0.03%]
基于市级的生活方式干预儿童超重和肥胖的4年随访BMI轨迹研究
Mette Fogh,Jane Nautrup Østergaard,Helene Kirkegaard et al.
Mette Fogh et al.
To examine 4-year changes in Body Mass Index z-score (BMIz) among children and adolescents with overweight or obesity who participated in municipality-based interventions, and to assess whether effects varied by age, sex or baseline weight ...
Aerobic Exercise Plus Hypocaloric Diet on Serum Leptin Concentrations in Adults With Primary Hypertension and Overweight/Obesity: Results From the EXERDIET-HTA Trial [0.03%]
有氧运动联合低热量饮食对原发性高血压合并超重或肥胖成人血清瘦素浓度的影响：EXERDIET-HTA试验结果
Virginia A Aparicio,Pablo Corres,Ilargi Gorostegi-Anduaga et al.
Virginia A Aparicio et al.
Hyperleptinaemia is an emerging mechanism involved in the pathogenesis of obesity-related primary hypertension (HTN). This substudy from a large clinical trial aimed to determine differences in [leptin] in physically inactive adults (n = 69...
Randomized Controlled Trial
Clinical obesity. 2026 Jun;16(3):e70080. DOI:10.1111/cob.70080 2026
Use of GLP-1 Analogues in Obesity and the Risk of Non-Arteritic Ischaemic Optic Neuropathy: Let's Clarify! [0.03%]
GLP-1受体激动剂与非动脉炎性缺血性视神经病变风险：需要厘清！
Giovanna Muscogiuri,Annamaria Colao
Giovanna Muscogiuri
Severe Obesity Management in a Large Academic Health System: A Retrospective Evaluation of Metabolic Bariatric Surgery Counselling Practices [0.03%]
大型学术医疗系统中重度肥胖管理的回顾性评估：代谢代谢手术咨询实践的回顾性评价
Mustafa Naveed,Elizabeth Gienger,Tonja Locklear et al.
Mustafa Naveed et al.
Metabolic and bariatric surgery (MBS) is an effective treatment for severe obesity but remains substantially underutilized. Limited data exist on outpatient counselling patterns preceding surgical uptake. Using electronic health record data...
Exploratory Analysis of Liraglutide Effects on Obstructive Sleep Apnea and Health-Related Quality of Life in Individuals With Obesity and COPD: A Secondary Analysis of a Randomised Controlled Trial [0.03%]
利拉鲁肽对肥胖伴慢性阻塞性肺病患者的阻塞性睡眠呼吸暂停及生活质量影响的探索性分析：一项随机对照试验的事后分析
Sofie Krogh Wolsing,Ayse Dudu Altintas Dogan,Claus Bogh Juhl et al.
Sofie Krogh Wolsing et al.
Obstructive sleep apnea (OSA) is associated with chronic obstructive pulmonary disease (COPD) and obesity, and all three are linked to reduced health-related quality of life (HRQoL). Coexistence of OSA and COPD increases morbidity and morta...
Randomized Controlled Trial
Clinical obesity. 2026 Apr;16(2):e70079. DOI:10.1111/cob.70079 2026
Misconceptions About Obesity and Weight Stigma in Brazilian Healthcare Professionals [0.03%]
巴西医疗专业人员对肥胖的误解和体重歧视
Paula Victoria Sozza,Eva Penelo,Stuart William Flint et al.
Paula Victoria Sozza et al.
People living with obesity (PLWO) frequently experience weight stigma (WS) in healthcare settings, leading to disparities in treatment. Although research shows that healthcare professionals (HCPs) often hold stigmatising views, this issue r...
Comparison of Semaglutide and Lifestyle Counselling for Weight Loss Using Multi-Site Electronic Health Records [0.03%]
利拉鲁肽与生活习惯指导的减重效果对比研究——基于多中心电子健康档案数据的分析
William J B Powell,Diego R Mazzotti,Stephen D Herrmann et al.
William J B Powell et al.
To evaluate the effectiveness of semaglutide compared with lifestyle counselling alone for weight loss in diabetic and non-diabetic patients with obesity. This multi-site, retrospective, observational study uses data from electronic health ...
Observational Study
Clinical obesity. 2026 Apr;16(2):e70076. DOI:10.1111/cob.70076 2026
GLP-1 Receptor Agonists Versus Bariatric Surgery: Effects of Weight Loss and BMI on Subsequent General Surgical Procedures [0.03%]
GLP-1受体激动剂与代谢手术：减重和BMI对后续普外科手术的影响如何？
Shahzaib Zindani,Selamawit Woldesenbet,Abdullah Altaf et al.
Shahzaib Zindani et al.
Obesity and T2DM substantially increase postoperative risk, with higher surgical site infections in obesity and up to a 65% increase in overall complications in T2DM. This study assesses the impact of weight loss interventions-metabolic bar...