Rising dementia mortality among tobacco users in the US, 2005-2020: insights from CDC-WONDER database [0.03%]
2005年至2020年美国烟草使用者痴呆症死亡率上升:来自CDC-WONDER数据库的启示
Maryam Saghir,Muhammad Affan,Eshal Saghir et al.
Maryam Saghir et al.
Background: Dementia is a leading cause of morbidity and mortality in the aging population, with tobacco use recognized as a major modifiable risk factor. Despite this established link, national trends in mortality due to...
A plain language summary on clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS study [0.03%]
克拉屈滨治疗复发性多发性硬化症的临床和机制效应的通俗概述:MAGNIFY-MS研究2年的结果
Klaus Schmierer,Heinz Wiendl,Frederik Barkhof et al.
Klaus Schmierer et al.
Analyzing multiple-sclerosis progression: stage-specific biomarker insights via explainable machine learning [0.03%]
利用可解释机器学习分析多发性硬化症的进程:通过分期特异性生物标志物洞察
Selahaddin Batuhan Akben,Ayşenur Bilirim,Cantürk Akben et al.
Selahaddin Batuhan Akben et al.
Background: Multiple Sclerosis (MS) is a chronic autoimmune disease where early diagnosis from Clinically Isolated Syndrome (CIS) remains challenging. Met...
Impact of region-based shape alterations in MRI as indicators of Parkinson's Disease [0.03%]
基于区域的形态变化在磁共振成像中作为帕金森病指示器的影响
Komal Singh,Ashish Khare
Komal Singh
Background: Parkinson's Disease (PD) is a neuro-degenerative condition that progressively impairs movement, resulting from the loss of dopamine-producing brain cells. Early detection of such a condition helps slowing thei...
Exploring maintenance of spatiotemporal gait parameters during internal and external rhythmic auditory cueing in Parkinson's disease [0.03%]
帕金森病患者在内部和外部节律性听觉提示下的时空步态参数维持规律的研究
Allison M Haussler,Sidney T Baudendistel,Elinor C Harrison et al.
Allison M Haussler et al.
Introduction: Rhythmic auditory cueing is a well-researched intervention to address gait impairment in Parkinson's disease (PD). Both external and internal music-based cues improve spatiotemporal gait variables. However, ...
Portuguese consensus for the use of cladribine tablets in multiple sclerosis [0.03%]
葡萄牙克利霉素片在多发性硬化治疗中的共识意见
João de Sá,Mariana Santos,Sónia Batista
João de Sá
Aims: Multiple sclerosis (MS) is a chronic immune-mediated neurodegenerative disease. Cladribine tablets, an immune reconstitution therapy, are approved for the treatment of highly active relapsing-remitting MS (RRMS). Ev...
Pilot randomized controlled trial of the ReFresh online fatigue management programme for people with Parkinson's disease [0.03%]
帕金森病患者的ReFresh在线疲劳管理项目的试点随机对照试验
Sarah Alageel,Jane Hibberd,Katherine H O Deane
Sarah Alageel
Aims: Fatigue is one of the most disabling symptoms experienced by people with Parkinson's disease, yet few evidence-based non-pharmacological interventions are available. This study evaluated the feasibility, acceptabili...
Registered Dietitians' perspectives on nutrition management of persons living with amyotrophic lateral sclerosis [0.03%]
注册营养师对管理肌萎缩侧索硬化患者营养状况的看法
Amy C Ellis,Stephanie Dobak,Keith Pearson et al.
Amy C Ellis et al.
Aim: Persons with amyotrophic lateral sclerosis (PALS) are at high risk for malnutrition, which is a negative prognostic factor for disease progression and survival. This study explored the perspectives of Registered Diet...
Plasma proteomic trajectories before the onset of neurodegenerative diseases [0.03%]
神经退行性疾病发病前血浆蛋白质组变化轨迹分析
Zhihan Zhang,Rui Fan,Sisi Jing et al.
Zhihan Zhang et al.
Background: The study aimed to identify indicative proteins associated with the occurrence and mortality of three neurodegenerative diseases (NDDs) and track the changes of proteins before the onset of NDDs. ...
The multifaceted nature of Friedreich ataxia: strategies for comprehensive patient care [0.03%]
friedreich共济失调的多面性:全面护理患者的策略
Muhammad Liaquat Raza,Mohadisa Asif Rawalia,Zainab Fatima et al.
Muhammad Liaquat Raza et al.
Friedreich's ataxia (FA) is a complicated disease that affects the nervous system and creates many problems for patients and doctors. This narrative review looks at the complex nature of FA, highlighting its various health issues that often...