Immune system modifications in atypical parkinsonism related to autoimmunity - a case control study [0.03%]
与自身免疫相关的非典型帕金森病的免疫系统改变-一项病例对照研究
Annamma Mathai,Sudheeran Kannoth,Vivek Nambiar et al.
Annamma Mathai et al.
Background: Inflammation is known in atypical parkinsonism (AP), but the role of autoimmunity is unclear. This study evaluates immune system modifications suggesting autoimmunity in AP. ...
Patient and healthcare provider experience of diroximel fumarate: considerations for selecting disease-modifying therapy [0.03%]
关于选择治疗药物:患者和医疗提供者对富马酸二氧米特的经验考虑事项
Cortnee Roman,Meghan Garabedian,Virginia R Schobel et al.
Cortnee Roman et al.
Purpose: To evaluate treatment perceptions of diroximel fumarate (DRF) for relapsing multiple sclerosis (MS), with contextual data from dimethyl fumarate (DMF) users, based on patient and healthcare provider (HCP) surveys...
Gait assessment using wearable technologies in neurological disorders: a rapid umbrella [0.03%]
可穿戴技术在神经系统疾病步态评估中的应用:伞式系统综述的快速回顾
Prajakta P Masurkar,Sagar Rikame
Prajakta P Masurkar
Background: Gait analysis is essential tool for tracking neurological disorders-Parkinson's disease (PD), stroke, Alzheimer's disease (AD), and multiple sclerosis (MS). Wearable technologies enable continuous, noninvasive...
Effects of triptolide herb on the progression of Alzheimer's disease preclinical models: a systematic review [0.03%]
三七总皂苷对阿尔茨海默病模型小鼠影响的系统评价研究进展
Rabab Shami,Rania El Majzoub,Ali Ismail et al.
Rabab Shami et al.
Aim: This study aims to systematically evaluate and synthesize preclinical evidence on the neuroprotective effects of Triptolide (Tri) in Alzheimer's disease (AD) models, focusing on its impact on amyloid-beta accumulatio...
N-acetylcysteine for Parkinson's disease: a translational systematic review of mechanistic and early clinical data [0.03%]
用于帕金森病的N-乙酰半胱氨酸:机制和早期临床数据的转化系统性回顾研究
Anas Mohammad,Mohammad Ibrahim,Moeez Akram et al.
Anas Mohammad et al.
Background: Parkinson's disease (PD) involves progressive motor and non-motor decline, linked to oxidative stress and glutathione depletion. N-acetylcysteine (NAC), a glutathione precursor and antioxidant, is a potential ...
Reviving mitochondria to restore the mind: stem cell-based bioenergetic rescue in Parkinson's disease [0.03%]
复苏线粒体以恢复大脑功能:帕金森病的干细胞生物能量救援疗法
Supriya Shidhaye,Anis Ahmad Chaudhary,Mayuri Gajghate et al.
Supriya Shidhaye et al.
Parkinson's disease is a neurodegenerative disorder of aging with dopaminergic neuronal degeneration in the substantia nigra leading to motor dysfunction. Mitochondrial dysfunction is central to its pathophysiology, leading to oxidative str...
Trends in mortality in elderly patients with Alzheimer's dementia and aspiration pneumonitis in the United States [0.03%]
美国老年阿尔茨海默病患者和吸入性肺炎死亡率的流行趋势分析
Hammad Jehangir,Ahmed Faizan,Dilawar Khan et al.
Hammad Jehangir et al.
Background: Alzheimer's dementia (AD) affects 6.9 million senior Americans and is a leading cause of death. Aspiration pneumonia carries high mortality but remains underexamined in this group. This study explores mortalit...
Synergistic effects of curcumin-donepezil therapy in a Drosophila Alzheimer's disease model [0.03%]
姜黄素-多奈哌齐联合治疗果蝇阿尔茨海默病模型的协同效应
Opeyemi B Ogunsuyi,Odunayo O Oluokun,Adedayo O Ademiluyi et al.
Opeyemi B Ogunsuyi et al.
Background: Despite emerging therapeutic options, Alzheimer´s disease (AD) management remains suboptimal due to multimodal pathogenesis. We investigated curcumin-donepezil combination therapy, as curcumin demonstrates an...
Rivastigmine for parkinsonian symptoms in dementia with Lewy bodies: a paradigm shift [0.03%]
路易体痴呆患者帕金森氏症状的石杉碱甲治疗:范式转变
Porimita Chutia,Shailendra Mohan Tripathi
Porimita Chutia
Introduction: Parkinsonian symptoms are one of the core features of Dementia with Lewy bodies (DLB), which has a prevalence of more than 80%. Management of DLB poses unique challenges as the treatment of one condition lea...
An evaluation of the ALSSQOL-SF in the Malaysian context through cognitive interviewing [0.03%]
认知访谈在马来西亚语境下评估ALS生存质量简表(ALSSQOL-SF)
Wafa Sabirin,Saiful Adni Abd Latif,Fazlina Ahmad et al.
Wafa Sabirin et al.
Background: Quality of life is an important goal of care for people living with amyotrophic lateral sclerosis (ALS) and their carers. The ALS Specific Quality of Life instrument Short Form (ALSSQOL-SF) has been translated...