Practices and perceptions around splitting of carbidopa/levodopa tablets: a survey of patients and neurologists [0.03%]
卡比多巴/左旋多巴片剂分掰的实践与认知:患者及神经科医生调查结果
Ramon L Rodriguez,Stuart H Isaacson,Yasar Torres-Yaghi et al.
Ramon L Rodriguez et al.
Background: Carbidopa/levodopa (CD/LD) remains the primary treatment for Parkinson's disease (PD) motor control symptoms. With progressing disease, for better symptom management, patients often split immediate-release CD/...
Exercise and cognition in people with degenerative cerebellar ataxia: a narrative review [0.03%]
退行性小脑共济失调患者中的运动与认知:综述文章
Chelsea E Macpherson,Meghan Bjalme-Evans,Fatima Awad et al.
Chelsea E Macpherson et al.
Background: Degenerative cerebellar disorders (DCDs) are a group of conditions that involve deterioration of neurons in the cerebellum. People with DCDs (PwDCD) present with multifaceted symptoms across motor (e.g., ataxi...
Shubha Joshi,Porimita Chutia,Shailendra Mohan Tripathi
Shubha Joshi
Paratonia is a type of hypertonia with involuntary resistance to passive movement depending on the pace and force being applied. People with paratonia may find it challenging to modify their movements and posture. Limited awareness among he...
Dancing through the darkness: a systematic review of dance as a multidimensional therapy for Parkinson's disease [0.03%]
踏破黑暗:舞蹈作为多维度帕金森病治疗的系统性综述
Rojin Vaseinasrabadi,Joseph DeSouza
Rojin Vaseinasrabadi
Introduction: Parkinson's disease (PD) is a progressive neurodegenerative disorder with no known cure, affecting both motor and non-motor functions. This review examines the therapeutic potential of dance as a holistic in...
Identifying a combination of biomarkers to predict treatment response to nabilone for agitation in Alzheimer's disease - an exploratory post hoc analysis [0.03%]
探索性事后分析:识别生物标志物组合以预测奈培洛酮治疗阿尔茨海默病激越反应效果
Hui Jue Wang,Myuri Ruthirakuhan,Ana C Andreazza et al.
Hui Jue Wang et al.
Background: To identify if a combination of blood-based biomarkers related to inflammation and oxidative stress predict treatment response to nabilone for Alzheimer's disease (AD)-associated agitation. ...
Coffee consumption and risk of multiple sclerosis (MS): a systematic review and meta-analysis [0.03%]
咖啡摄入与多发性硬化症风险的关系:系统评价和Meta分析
Mohsen Rastkar,Erfan Jannatalipour,Aida Mohamadi et al.
Mohsen Rastkar et al.
Background: We designed this systematic review and meta-analysis to estimate a pooled odds ratio of developing MS by coffee consumption. Methods: ...
Lingual pressure as a physiological indicator for dysphagia in amyotrophic lateral sclerosis and multiple system atrophy [0.03%]
肌萎缩侧索硬化和多系统萎缩中舌压作为吞咽困难的生理指标
Jin Magara,Taku Suzuki,Midori Yoshihara et al.
Jin Magara et al.
Background: This study aimed to characterize lingual pressure (LP) and clarify its association with dysphagia in patients with amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). ...
Guidelines addressing Motor Neurone Disease (MND): a scoping review [0.03%]
关于 motor neurone disease(MND)的指南:系统综述研究
Cindy Stern,Ines Semendric,Nipun Shrestha et al.
Cindy Stern et al.
Introduction: Motor Neurone Disease (MND) is a debilitating neurodegenerative condition affecting individuals, families, and carers. Evidence-informed care can improve outcomes, and guidelines play a key role in supportin...
Nannan Qian,Chengcheng Lu,Yufei Qian et al.
Nannan Qian et al.
This case report describes a 54-year-old Chinese woman with progressive gait instability, speech slowing, and cerebellar ataxia. Initial symptoms included mild bradykinesia and frequent backward falls. Neurological evaluation revealed supra...
Exploring the mid-term impact of telemonitoring in Parkinson's disease: insights from adoption into clinical practice [0.03%]
远程监控在帕金森病中期影响的临床应用启示
Foivos S Kanellos,Eleni Kosmidi,Georgios Rigas et al.
Foivos S Kanellos et al.
Background: Routine clinical evaluations offer limited insight into daily variability and disease progression in Parkinson's disease (PD). While wearable devices are increasingly used to improve patient monitoring, eviden...