Patient-reported benefits from nabiximols treatment in multiple sclerosis-related spasticity exceed conventional measures [0.03%]
纳比欣醇治疗多发性硬化症相关痉挛的患者报告效益超过常规措施
Michael R Haupts,Ute Essner,Mathias Mäurer
Michael R Haupts
Aim: This prospective, multicenter, open-label, noninterventional 12-week study investigated the effectiveness and tolerability of add-on nabiximols oromucosal spray (Sativex®) in the real-world setting in Germany. Patients & methods: The ...
An overview of the worldwide distribution of LRRK2 mutations in Parkinson's disease [0.03%]
帕金森病中LRRK2突变的世界分布概况
Hicham El Otmani,Mohamed Daghi,Nadia Tahiri Jouti et al.
Hicham El Otmani et al.
Parkinson's disease (PD) is a neurodegenerative disorder with significant genetic influence. The LRRK2 gene is a major genetic contributor, particularly the Gly2019Ser mutation. This focused review investigates the global distribution of LR...
An innovative approach to recruiting participants for dementia research: primary care and researcher perspectives [0.03%]
痴呆研究参与者招募的新方法：初级保健和研究人员的角度观点
Linda Lee,Loretta M Hillier,Tejal Patel et al.
Linda Lee et al.
Aim: To describe clinician and researcher perceptions of a new, patient preference focused approach to recruiting patients for research from primary care-based memory clinics. Methods: Memory clinic clinicians completed a survey and key inf...
Free-Cog revisited: the diagnostic contribution of cognitive and executive function [0.03%]
Free-Cog再审视：认知和执行功能的诊断贡献
Andrew J Larner,Alistair Burns
Andrew J Larner
Aim: To examine Free-Cog, a recently described, hybrid screening instrument, as separate tests of cognitive (Free-Cog-Cog) and executive function (Free-Cog-Exec) to see if this improved screening accuracy for cognitive impairment compared w...
Piecing together the Alzheimer's puzzle: Lecanemab's role in treatment [0.03%]
拼接阿尔茨海默病的拼图：莱卡内单抗在治疗中的作用
Danish Ali Ashraf,Hassan Tariq,Fathimath Shahaa Hassan et al.
Danish Ali Ashraf et al.
People with neuromuscular diseases and their relatives' perspectives on challenges in everyday life and healthcare [0.03%]
神经肌肉疾病患者及其亲属对日常生活和医疗保健挑战的看法
Charlotte Handberg,Ulla Werlauff
Charlotte Handberg
Objective: People with a neuromuscular disease (NMD) often experience challenges in everyday life and healthcare. Aim: To investigate experiences of and perspectives on challenges in everyday life and healthcare of people with NMDs and thei...
Comparison of diagnostic routines for suspected Alzheimer's disease patients in US-American and German primary care [0.03%]
美国和德国初级保健中疑似阿尔茨海默病患者的诊断流程比较
Felix Menne,Timo Grimmer,Carola G Schipke
Felix Menne
Aim: Thorough diagnostics are a prerequisite for the optimal treatment of Alzheimer's disease (AD). Biomarker-based diagnostics are standard in academia, data on practitioners' diagnostic workups is scarce. Materials & methods: Surveys in G...
Satisfaction and practicality of a prefilled glatiramer acetate pen in relapsing-remitting multiple sclerosis patients [0.03%]
预装的醋酸格拉替雷笔在复发缓解型多发性硬化症患者中的满意度和实用性研究
Herbert Schreiber,Joachim Hipp,Fabian Roßnagel et al.
Herbert Schreiber et al.
Aim: Evaluation of practicality and patient satisfaction of a glatiramer acetate (GA) prefilled pen in patients with relapsing-remitting multiple sclerosis (RRMS). Patients & methods: A cross-sectional, multicenter, observational study eval...
Observational Study
Neurodegenerative disease management. 2023 Oct;13(5):281-288. DOI:10.2217/nmt-2022-0031 2023
A study of once-a-week donepezil transdermal system's bioequivalence to oral donepezil in healthy volunteers: a plain language summary [0.03%]
每周一次多奈哌齐透皮给药系统与健康受试者口服多奈哌齐生物等效性研究的白话文摘要
Rene Braeckman,Charles Oh
Rene Braeckman
What is this summary about?: This is a plain language summary of an article published in the Journal of Alzheimer's Disease. It describes an adhesive patch placed on the skin's surface, also referred to as a transdermal d...
A plain language summary on assessing the long-term effectiveness of cladribine tablets in people living with relapsing multiple sclerosis: The CLASSIC-MS study [0.03%]
有关评估克拉利odbind片剂在复发性多发性硬化症患者中长期有效性的研究：CLASSIC-MS研究的简易总结
Gavin Giovannoni,Alexey Boyko,Jorge Correale et al.
Gavin Giovannoni et al.
What is this summary about?: Previous studies have shown that people living with multiple sclerosis (MS) treated with cladribine tablets have fewer relapses (where new symptoms occur or existing symptoms get worse for 24 ...