Detecting copy number variations from array CGH data based on a conditional random field model [0.03%]
基于条件随机场模型的数组 Comparative Genomic Hybridization 数据中拷贝数变异检测方法研究
Xiao-Lin Yin,Jing Li
Xiao-Lin Yin
Array comparative genomic hybridization (aCGH) allows identification of copy number alterations across genomes. The key computational challenge in analyzing copy number variations (CNVs) using aCGH data or other similar data generated by a ...
Ali Cakmak,Gultekin Ozsoyoglu,Richard W Hanson
Ali Cakmak
Metabolism is a representation of the biochemical principles that govern the production, consumption, degradation, and biosynthesis of metabolites in living cells. Organisms respond to changes in their physiological conditions or environmen...
Understanding distal transcriptional regulation from sequence, expression and interactome perspectives [0.03%]
从序列、表达和相互作用网络的角度理解远端转录调控
Arvind Rao,David J States,Alfred O Hero rd et al.
Arvind Rao et al.
Gene regulation in eukaryotes involves a complex interplay between the proximal promoter and distal genomic elements (such as enhancers) which work in concert to drive precise spatio-temporal gene expression. The experimental localization a...
Misael Mongiovì,Raffaele Di Natale,Rosalba Giugno et al.
Misael Mongiovì et al.
Network querying is a growing domain with vast applications ranging from screening compounds against a database of known molecules to matching sub-networks across species. Graph indexing is a powerful method for searching a large database o...
Classification and identification of fungal sequences using characteristic restriction endonuclease cut order [0.03%]
基于特征性限制性内切酶切割顺序的真菌序列分类及识别方法研究
Rajib Sengupta,Dhundy R Bastola,Hesham H Ali
Rajib Sengupta
Restriction Fragment Length Polymorphism (RFLP) is a powerful molecular tool that is extensively used in the molecular fingerprinting and epidemiological studies of microorganisms. In a wet-lab setting, the DNA is cut with one or more restr...
Ying Xu,Peter Markstein
Ying Xu
Dietrich Rebholz-Schuhmann,Antonio José Jimeno Yepes,Erik M Van Mulligen et al.
Dietrich Rebholz-Schuhmann et al.
The CALBC initiative aims to provide a large-scale biomedical text corpus that contains semantic annotations for named entities of different kinds. The generation of this corpus requires that the annotations from different automatic annotat...
Yutaka Sasaki,John McNaught,Sophia Ananiadou
Yutaka Sasaki
This paper demonstrates that a large-scale lexicon tailored for the biology domain is effective in improving question analysis for genomics Question Answering (QA). We use the TREC Genomics Track data to evaluate the performance of differen...
Makoto Miwa,Rune Saetre,Jin-Dong Kim et al.
Makoto Miwa et al.
Biomedical Natural Language Processing (BioNLP) attempts to capture biomedical phenomena from texts by extracting relations between biomedical entities (i.e. proteins and genes). Traditionally, only binary relations have been extracted from...
Wrestling with biomedical research results: language resources and literature analysis. Introduction [0.03%]
生物医学研究成果的语言资源和文献分析介绍与讨论
D Rebholz-Schuhmann,Nigel Collier,Jong C Park et al.
D Rebholz-Schuhmann et al.