Hui Yu,Kang Tu,Lu Xie et al.
Hui Yu et al.
With regards to well-replicated two-conditional microarray datasets, the selection of differentially expressed (DE) genes is a well-studied computational topic, but for multi-conditional microarray datasets with limited or no replication, t...
Cancer classification from the gene expression profiles by Discriminant Kernel-PLS [0.03%]
基于判别核-PLS的肿瘤分类方法研究基因表达谱数据
Kai-Lin Tang,Wei-Jia Yao,Tong-Hua Li et al.
Kai-Lin Tang et al.
Cancer diagnosis depending on microarray technology has drawn more and more attention in the past few years. Accurate and fast diagnosis results make gene expression profiling produced from microarray widely used by a large range of researc...
Efficient mining of haplotype patterns for linkage disequilibrium mapping [0.03%]
有效挖掘连锁不平衡图谱的单倍体型模式
Li Lin,Limsoon Wong,Tze-Yun Leong et al.
Li Lin et al.
Effective identification of disease-causing gene locations can have significant impact on patient management decisions that will ultimately increase survival rates and improve the overall quality of health care. Linkage disequilibrium mappi...
Racial differences in MLH1 and MSH2 mutation: an analysis of yellow race and white race based on the InSiGHT database [0.03%]
黄种人和白种人MLH1和MSH2基因突变差异的分析基于InSiGHT数据库
Wenqian Wei,Lei Liu,Jian Chen et al.
Wenqian Wei et al.
MLH1 and MSH2 mutations underlie 90% of hereditary nonpolyposis colorectal cancer (HNPCC) mutations. The International Society of Gastrointestinal Hereditary Tumors (InSiGHT) has established an international database of mutations associated...
G6PD-MutDB: a mutation and phenotype database of glucose-6-phosphate (G6PD) deficiency [0.03%]
G6PD-MutDB：葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症突变和表型数据库
Xin Zhao,Zuofeng Li,Xiaoyan Zhang
Xin Zhao
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common hereditary enzymatic disorder of red blood cells in humans due to mutations in the G6PD gene. The G6PD enzyme catalyzes the first step in the pentose phosphate pathway t...
Environmental dependency of gene knockouts on phenotype microarray analysis in Escherichia coli [0.03%]
基于环境依赖的基因敲除对大肠杆菌表型微阵列分析的影响
Yukako Tohsato,Tomoya Baba,Yusaku Mazaki et al.
Yukako Tohsato et al.
Systematic studies have revealed that single gene deletions often display little phenotypic effects under laboratory conditions and that in many cases gene dispensability depends on the experimental conditions. To elucidate the environmenta...
J B Brown,Takashi Urata,Takeyuki Tamura et al.
J B Brown et al.
High accuracy is paramount when predicting biochemical characteristics using Quantitative Structural-Property Relationships (QSPRs). Although existing graph-theoretic kernel methods combined with machine learning techniques are efficient fo...
A method based on local density and random walks for complexes detection in protein interaction networks [0.03%]
基于局部密度和随机游走的蛋白质相互作用网络复合物识别算法
Liang Yu,Lin Gao,Kui Li
Liang Yu
In this paper, we present a method based on local density and random walks (LDRW) for core-attachment complexes detection in protein-protein interaction (PPI) networks whether they are weighted or not. Our LDRW method consists of two stages...
Stepwise origin and functional diversification of the AFL subfamily B3 genes during land plant evolution [0.03%]
陆地植物进化过程中AFL亚家族B3基因的逐步起源和功能多样化
Yang Li,Ke Jin,Zhu Zhu et al.
Yang Li et al.
The AFL genes (ABI3/VP1, FUS3 and LEC2) belong to the plant-specific B3 superfamily, playing important roles in regulating seed development and maturation. It is unclear, however, whether these genes appeared at the same time as the origin ...
Tsan-Huang Shih,Chien-Ming Chen,Hsin-Wei Wang et al.
Tsan-Huang Shih et al.
Biomolecule sequences and structures of land, air and water species are determined rapidly and the data entries are unevenly distributed for different organisms. It frequently leads to the BLAST results of homologous search containing undes...