Hongyuan Jia,Xingmin Chen,Linling Zhang et al.
Hongyuan Jia et al.
Cancer-associated fibroblasts (CAFs) are key players in cancer development and therapy, and they exhibit multifaceted roles in the tumor microenvironment (TME). From their diverse cellular origins, CAFs undergo phenotypic and functional tra...
Po-Lan Su,Naoki Furuya,Alahmadi Asrar et al.
Po-Lan Su et al.
The development of targeted therapy with small-molecule tyrosine kinase inhibitors and immunotherapy with immune checkpoints inhibitors has ushered in the era of precision medicine in treating lung cancer, which remains the leading cause of...
Correction: WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome [0.03%]
修正：WT1-mRNA树突状细胞疫苗治疗多形性胶质母细胞瘤，恶性胸膜间皮瘤，转移性乳腺癌和其它实体肿瘤患者：类型1T淋巴细胞反应与临床结果相关
Zwi N Berneman,Maxime De Laere,Paul Germonpré et al.
Zwi N Berneman et al.
Published Erratum
Journal of hematology & oncology. 2025 Mar 19;18(1):34. DOI:10.1186/s13045-025-01683-5 2025
Correction: myCAF-derived Exosomal PWAR6 accelerates CRC liver metastasis via altering glutamine availability and NK cell function in the tumor microenvironment [0.03%]
修正：来自myCAF的胞外囊泡PWAR6通过改变肿瘤微环境中的谷氨酰胺可用性和NK细胞功能来加速结直肠癌肝转移
Hongsheng Fang,Weixing Dai,Ruiqi Gu et al.
Hongsheng Fang et al.
Published Erratum
Journal of hematology & oncology. 2025 Mar 18;18(1):31. DOI:10.1186/s13045-025-01685-3 2025
Unraveling the triad of hypoxia, cancer cell stemness, and drug resistance [0.03%]
解开低氧、癌症细胞干性和药物抵抗三者的关系
Tongxuan Shang,Ziqi Jia,Jiayi Li et al.
Tongxuan Shang et al.
In the domain of addressing cancer resistance, challenges such as limited effectiveness and treatment resistance remain persistent. Hypoxia is a key feature of solid tumors and is strongly associated with poor prognosis in cancer patients. ...
Mirvetuximab soravtansine: current and future applications [0.03%]
Mirvetuximab Soravtansine：当前和未来应用
Beihua Kong,Wenxin Zheng
Beihua Kong
Ovarian epithelial cancer (OEC), particularly high-grade serous carcinoma (HGSC), remains a clinical challenge due to its late-stage diagnosis, high recurrence rates, and poor survival outcomes. Mirvetuximab soravtansine (MIRV), an antibody...
Second primary malignancies following CAR T-cell therapy in patients with hematologic malignancies [0.03%]
CAR T细胞治疗血液肿瘤患者后继发的第二原发恶性肿瘤问题
Elvira Umyarova,Charles Pei,William Pellegrino et al.
Elvira Umyarova et al.
Chimeric antigen receptor T-cell (CAR-T) therapy has transformed the management of patients with relapsed/refractory (R/R) hematologic malignancies, including B-cell lymphomas and multiple myeloma (MM). While data pertaining to the efficacy...
Lina Fu,Xuerong Zhou,Xiaoyu Zhang et al.
Lina Fu et al.
Lymphoma, a malignant tumor derived from lymphocytes and lymphoid tissues, presents with complex and heterogeneous clinical manifestations, requiring accurate patient classification for appropriate treatment. While invasive pathological exa...
Novel targeted therapies for immunoglobulin light chain amyloidosis: latest updates from the 2024 ASH annual meeting [0.03%]
免疫球蛋白轻链淀粉样变性的新型靶向疗法：来自2024年ASH年会的最新更新
Qiling Bu,Hong-Hu Zhu,Wenming Chen
Qiling Bu
Immunoglobulin light chain (AL) amyloidosis is an incurable disease caused by the accumulation and sedimentation of unstable free light chains produced by monoclonal plasma cells. The key to treatment is to achieve a deep hematologic remiss...
Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer [0.03%]
sorcin-PAX5蛋白-蛋白相互作用的破坏通过促进FBXL12介导的ALDH1A1泛素化诱导胰腺癌细胞铁死亡
Yahui Ding,Yongping Bai,Tianyang Chen et al.
Yahui Ding et al.
Background: Pancreatic cancer is one of the most malignant cancers, and limited therapeutic options are available. The induction of ferroptosis is considered to be a novel, promising strategy that has potential in cancer ...