Inhibition of Toxic IAPP Amyloid by Extracts of Common Fruits [0.03%]
常见水果提取物通过抑制毒性IAPP淀粉样蛋白聚集防治2型糖尿病并发症的研究进展
Pei-Yu Kao,Evangeline Green,Catalina Pereira et al.
Pei-Yu Kao et al.
The aggregation of the 37-amino acid polypeptide islet amyloid polypeptide (IAPP, amylin), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of pancreatic β-islet cells in type 2 diabetes. It is ...
Anti-inflammatory effects of 4'-demethylnobiletin, a major metabolite of nobiletin [0.03%]
虾青素主要代谢产物去甲基虾青素的抗炎作用研究
Xian Wu,Mingyue Song,Kanyasiri Rakariyatham et al.
Xian Wu et al.
Nobiletin, a citrus flavonoid has been associated with various beneficial biological activities. 4'-Demethylnobiletin (4DN) is a major metabolite of nobiletin and its tissue level was found to be much higher than that of nobiletin after ora...
The impact of green tea polyphenols on development and reproduction in Drosophila melanogaster [0.03%]
绿茶儿茶素对果蝇发育和生殖的影响研究
Terry E Lopez,Hoang M Pham,Julia Barbour et al.
Terry E Lopez et al.
Although, green tea has numerous health benefits, adverse effects with excessive consumption have been reported. Using Drosophila melanogaster, a decrease in male fertility with green tea was evidenced. Here, the extent of green tea toxicit...
Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli [0.03%]
蔓越莓（大果越橘）低聚糖减少尿路致病性大肠杆菌生物被膜的形成
Jiadong Sun,Jannie P J Marais,Christina Khoo et al.
Jiadong Sun et al.
The preventive effects of the American cranberry (Vaccinium macrocarpon) against urinary tract infections are supported by extensive studies which have primarily focused on its phenolic constituents. Herein, a phenolic-free carbohydrate fra...
The catechol- O-methyltransferase inhibitor, tolcapone, increases the bioavailability of unmethylated (-)-epigallocatechin-3-gallate in mice [0.03%]
儿茶酚-O-甲基转移酶抑制剂托卡朋可增加小鼠体内未甲基化（-）-表没食子儿茶素-3-没食子酸酯的生物利用度
Sarah C Forester,Joshua D Lambert
Sarah C Forester
(-)-Epigallocatechin-3-gallate (EGCG), has been shown to inhibit cancer in vivo. EGCG, however, is rapidly methylated by catechol-O-methyl transferase (COMT), which reduces its cancer preventive efficacy. Tolcapone (TOL), is a clinically-us...
Dietary compounds galangin and myricetin suppress ovarian cancer cell angiogenesis [0.03%]
dietary compounds galangin和myricetin抑制卵巢癌细胞的血管生成
Haizhi Huang,Allen Y Chen,Yon Rojanasakul et al.
Haizhi Huang et al.
Galangin and myricetin are flavonoids isolated from vegetables and fruits which exhibit anti-proliferative activity in human cancer cells. In this study, their anti-angiogenic effects were investigated with in vitro (HUVEC) and in vivo (CAM...
Decaffeinated Green Tea and Voluntary Exercise Induce Gene Changes Related to Beige Adipocyte Formation in High Fat-Fed Obese Mice [0.03%]
无咖啡因绿茶和自愿运动通过改变与 beige 脂肪细胞形成相关的基因诱导小鼠体内白色脂肪组织成功转化为棕色脂肪组织
Sudathip Sae-Tan,Connie J Rogers,Joshua D Lambert
Sudathip Sae-Tan
We have previously reported that decaffeinated green tea extract (GTE) in combination with voluntary exercise (Ex) reduces metabolic syndrome in high fat-fed C57BL/6J mice. Here, we examined for the first time the effect of treatment with 7...
Galacto-oligosaccharides and Colorectal Cancer: Feeding our Intestinal Probiome [0.03%]
半乳糖低聚糖和结直肠癌：喂养我们的肠道益生菌
Jose M Bruno-Barcena,M Andrea Azcarate-Peril
Jose M Bruno-Barcena
Prebiotics are ingredients selectively fermented by the intestinal microbiota that promote changes in the microbial community structure and/or their metabolism, conferring health benefits to the host. Studies show that β (1-4) galacto-olig...
trans-10, cis-12 CLA promotes osteoblastogenesis via SMAD mediated mechanism in bone marrow mesenchymal stem cells [0.03%]
反式10，顺式12CLA通过SMAD介导的机制促进骨髓间充质干细胞成骨细胞生成分化
Jonggun Kim,Yooheon Park,Yeonhwa Park
Jonggun Kim
The inverse relationship between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells has been linked to overall bone mass. It has previously been reported that conjugated linoleic acid (CLA) inhibits adipogenesis ...
Microencapsulation of Lactobacillus acidophilus NCIMB 701748 in matrices containing soluble fibre by spray drying: Technological characterization, storage stability and survival after in vitro digestion [0.03%]
以喷雾干燥法制备含有可溶性纤维的包埋Lactobacillus acidophilus NCIMB 701748微胶囊：技术表征、储藏稳定性及体外消化存活率
Lina Yonekura,Han Sun,Christos Soukoulis et al.
Lina Yonekura et al.
We evaluated sodium alginate, chitosan and hydroxypropyl methylcellulose (HPMC) as co-encapsulants for spray dried Lactobacillus acidophilus NCIMB 701748 by assessing their impact on cell viability and physicochemical properties of the drie...