Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development [0.03%]
默克开放全球健康图书馆体外筛选出两种新的抗血吸虫病活性物质
Monique Evelyn Ueberall,Martina Berchthold,Cécile Häberli et al.
Monique Evelyn Ueberall et al.
Background: Schistosomiasis, which is caused by the parasite Schistosoma mansoni as well as other species of the trematode genus Schistosoma, leads to chronic inflammation and finally to liver fibrosis. If untreated, the ...
On the tracks of an uninvited guest, the Asian tiger mosquito, Aedes albopictus in Cyprus [0.03%]
追踪不速之客——入侵塞浦路斯的亚洲虎蚊(Aedes albopictus)
Riccardo Piccinno,Giulia Fiorenza,Marlen Ines Vasquez et al.
Riccardo Piccinno et al.
Background: Aedes albopictus, the Asian tiger mosquito, which is listed among the world's 100 most dangerous invasive species, is the main vector of chikungunya, dengue and Zika viruses. This mosquito species has rapidly ...
Bioassays for the evaluation of the attractiveness of attractive targeted sugar bait (ATSB) against Anopheles mosquitoes in controlled semi-field systems [0.03%]
评估吸引性目标糖饵(ATSB)对按蚊吸引力的生物测定方法——有控制的人工半 field 系统中的评价研究
Frank S C Tenywa,Ummi A Kibondo,Julian Entwistle et al.
Frank S C Tenywa et al.
Background: Sugar feeding is an essential aspect of mosquito biology that may be exploited for mosquito control by adding insecticides to sugar attractants, so-called 'attractive targeted sugar baits' (ATSBs). To optimize...
Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina [0.03%]
从感染巴贝斯虫病的雌性微小扇头蜱中进行血细胞转录组分析
Rubikah Vimonish,Janaina Capelli-Peixoto,Wendell Johnson et al.
Rubikah Vimonish et al.
Background: Tick hemolymph is a sterile fluid that carries nutrients to maintain tick health. The hemolymph creates a hostile environment for invaders including the destruction of microorganisms by its circulating hemocyt...
AxiWorm: a new tool using YOLOv5 to test antiparasitic drugs against Trichinella spiralis [0.03%]
AxiWorm:一种使用YOLOv5检测螺旋菌的抗寄生虫药物的新工具
Javier Sánchez-Montejo,Miguel Marín,María Alejandra Villamizar-Monsalve et al.
Javier Sánchez-Montejo et al.
Background-objective: Trichinella spiralis drug development and control need an objective high throughput system to assess first stage larvae (L1) viability. YOLOv5 is an image recognition tool easily trained to count mus...
High, but variable prevalence of Sarcocystis cruzi infections in farm-raised American bison (Bison bison) beef destined for human consumption [0.03%]
源自放养的美洲野牛( Bison bison)肉中的Sarcocystis cruzi感染呈高度但可变的流行率,并且该肉供人类消费
Larissa S de Araujo,Aditya Gupta,Marianne Dias Papadopoulos et al.
Larissa S de Araujo et al.
Background: Bison (Bison bison) and cattle (Bos taurus) are closely related (can interbreed) and they also share many parasites. Cattle are commonly infected with one or more of the eight named Sarcocystis species: Sarcoc...
Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges [0.03%]
蚊子的中部肠道免疫谱分析及其ABC转运蛋白基因的功能鉴定:系统性和局部细菌挑战的研究
Vikas Kumar,Shilpi Garg,Diksha Sisodia et al.
Vikas Kumar et al.
Background: The mosquito midgut is crucial for digestion and immune interactions. It produces several immune factors that protect the organ from invading pathogens and can limit their propagation. Studies on mosquito midg...
Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease [0.03%]
利用毒液毒素进行虫媒病的半转基因防治研究
Stephanie French,Rachael Da Silva,Janet Storm et al.
Stephanie French et al.
Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. They pose a significant risk to public health with over 200 million cases of malaria per annum and approx...
Decision tree-based learning and laboratory data mining: an efficient approach to amebiasis testing [0.03%]
基于决策树的学习和实验数据分析:有效进行溶组织内阿米巴检测的方法
Enas Al-Khlifeh,Ahmad S Tarawneh,Khalid Almohammadi et al.
Enas Al-Khlifeh et al.
Background: Amebiasis represents a significant global health concern. This is especially evident in developing countries, where infections are more common. The primary diagnostic method in laboratories involves the micros...