CD44 is a prognostic biomarker and correlated with immune infiltrates in gastric cancer [0.03%]
CD44是胃癌预后生物标志物并与免疫浸润相关
Weiyan Hou,Lingwei Kong,Zhiping Hou et al.
Weiyan Hou et al.
Objective: Gastric carcinoma is the most common malignant tumour of the human digestive system worldwide. CD44 serves as a marker for several tumour stem cells, including gastric cancer. However, the prognostic value of C...
Integrated analysis and exploration of potential shared gene signatures between carotid atherosclerosis and periodontitis [0.03%]
颈动脉粥样硬化和牙周炎潜在共有基因特征的综合分析与探索
Youjie Zeng,Si Cao,Minghua Chen
Youjie Zeng
Background: Increasing evidence has suggested an association between carotid atherosclerosis (CAS) and periodontitis (PD); however, the mechanisms have not been fully understood. This study aims to investigate the shared ...
Case-control study on CYP4B1 gene polymorphism and susceptibility to gastric cancer in the chinese Han population [0.03%]
CYP4B1基因多态性与汉族人胃癌易感性的病例对照研究
Shuyong Yu,Zhuang Chen,Jiajia Cheng et al.
Shuyong Yu et al.
Background: In China, gastric cancer (GC) is one of the most common malignant tumors. This study aimed to explore the relationship of rs2297810, rs4646491 and rs2297809 polymorphisms of CYP4B1 with susceptibility to GC in...
An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma [0.03%]
基于天冬酰胺代谢的分类揭示了肝细胞癌的代谢和免疫异质性
Jianguo Bai,Ruifeng Tang,Keyu Zhou et al.
Jianguo Bai et al.
Introduction and objectives: hepatocellular carcinoma (HCC) is the major form of liver cancer with a poor prognosis. Amino acid metabolism has been found to alter in cancers and contributes to malignant progression. Howev...
A likely pathogenic POLD1 variant associated with mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome in a Chinese patient [0.03%]
POLD1基因病理性变异与中国患者下颌发育不全性聋早衰综合征和脂代谢障碍症的关联分析
Bin Zuo,Hongen Xu,Zhaoyu Pan et al.
Bin Zuo et al.
Background: Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome (MDPL; OMIM# 615381) is a rare autosomal dominant disorder, with only a few reported cases worldwide. Herein, we describe the cli...
Role of a lipid metabolism-related lncRNA signature in risk stratification and immune microenvironment for colon cancer [0.03%]
结肠癌中与脂质代谢相关长链非编码RNA标志物的预后价值及免疫微环境作用研究
Yaobin Lin,Yu Xiao,Shan Liu et al.
Yaobin Lin et al.
Background: Energy metabolism disorder, especially lipid metabolism disorder, is an important biological characteristic of colon cancer. This research sought to examine the association between lipid metabolism-related lon...
Integrative analyses of immune-related biomarkers and associated mechanisms in coronary heart disease [0.03%]
冠心病相关免疫标志物的整合分析及机制探讨
Lianbo Zhang,Guibin Li,Bo Liang et al.
Lianbo Zhang et al.
Various studies showed that the effect of immune activation is pro-atherogenic and coronary heart disease (CHD) should therefore be considered an autoimmune disease. This study aimed to identify potential immune-related biomarkers, pathways...
Turning up the heat on non-immunoreactive tumors: autophagy influences the immune microenvironment in pancreatic cancer [0.03%]
提高对非免疫反应性肿瘤的关注：自噬影响胰腺癌的免疫微环境
Si-Yuan Lu,Jie Hua,Jiang Liu et al.
Si-Yuan Lu et al.
Background: Autophagy regulators play important roles in the occurrence and development of a variety of tumors and are involved in immune regulation and drug resistance. However, the modulatory roles and prognostic value ...
Hampig Raphael Kourie,Bahaa Succar,Eliane Chouery et al.
Hampig Raphael Kourie et al.
Background: Bladder cancer (BC) is the 10th most frequent tumor worldwide. Evidence shows an association between elevated risk of BC and various single nucleotide polymorphisms (SNP). BC incidence was the highest in Leban...
A heterozygous missense variant in the YWHAG gene causing developmental and epileptic encephalopathy 56 in a Chinese family [0.03%]
YWHAG基因错义杂合变异导致的一家系发育性和癫痫性脑病56型
Zhi Yi,Zhenfeng Song,Jiao Xue et al.
Zhi Yi et al.
Background: Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of severe disorders that are characterized by early-onset, refractory seizures and developmental slowing or regression. Genetic var...