Systematic review of observational research studying the long-term use of antithrombotic medicines following intracerebral hemorrhage [0.03%]
系统评价：基于脑出血后抗凝血药物长期使用的观察性研究
Robert W V Flynn,Thomas M MacDonald,Gordon D Murray et al.
Robert W V Flynn et al.
Patients with intracerebral hemorrhage frequently have indications for antithrombotic therapy. This represents a therapeutic dilemma as intracerebral hemorrhage is considered a contraindication to antithrombotic medication. Previous systema...
Paradoxical decrease in high-density lipoprotein cholesterol with fenofibrate: a quite rare phenomenon indeed [0.03%]
非诺贝特导致高密度脂蛋白胆固醇不升反降的现象实属罕见
Giuliana Mombelli,Franco Pazzucconi,Alighiero Bondioli et al.
Giuliana Mombelli et al.
Some recent clinical reports have suggested that paradoxical decreases in high-density lipoprotein cholesterol (HDL-C) levels after fenofibrate treatment may be quite common. These appear to occur mainly in patients with combined fibrate/st...
Beneficial effects of L- and N-type calcium channel blocker on glucose and lipid metabolism and renal function in patients with hypertension and type II diabetes mellitus [0.03%]
L型及N型钙通道阻断剂对高血压合并2型糖尿病患者糖脂代谢和肾功能的有益影响
Takashi Masuda,Misao N Ogura,Tatsumi Moriya et al.
Takashi Masuda et al.
It has been proved that cilnidipine has N-type calcium channels inhibitory activity as well as L-type calcium channels and inhibits excessive release of norepinephrine from the sympathetic nerve ending. This study was undertaken to compare ...
Long-term survival of routine implantable cardioverter/defibrillator recipients appears to be significantly impaired with concomitant diuretics and improved with aldosterone antagonists [0.03%]
长期植入式心脏复律除颤器伴随利尿剂和醛固酮拮抗剂的接受者的生存情况研究
Martin Stockburger,Alice Krebs,Oezlem Celebi et al.
Martin Stockburger et al.
Evidence-based treatment for heart failure (HF) comprises beta-blockers, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists (ARA). Diuretics (DR) are prescribed in acute and chronic...
Effects of multiple doses of clarithromycin on the pharmacokinetics of laropiprant in healthy subjects [0.03%]
多次服用克拉霉素对健康受试者拉匹普兰药代动力学的影响
Ying-Hong Wang,Jules I Schwartz,Wen-Lin Luo et al.
Ying-Hong Wang et al.
Laropiprant is a selective antagonist of the prostaglandin D2 receptor subtype 1, and is primarily eliminated via glucuronidation with a minor contribution from oxidative metabolism via CYP3A. The effects of multiple oral doses of clarithro...
Randomized Controlled Trial
Cardiovascular therapeutics. 2011 Apr;29(2):140-5. DOI:10.1111/j.1755-5922.2009.00129.x 2011
Effects of long-term disease-modifying antirheumatic drugs on endothelial function in patients with early rheumatoid arthritis [0.03%]
长效疾病修饰抗风湿药对早期类风湿关节炎患者内皮功能的影响
M Turiel,L Tomasoni,S Sitia et al.
M Turiel et al.
Rheumatoid arthritis (RA) is associated with enhanced atherosclerosis and impaired endothelial function early after the onset of the disease and cardiovascular (CV) disease represents one of the leading causes of morbidity and mortality. It...
Baseline characteristics of the Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial population: comparison with other diabetes prevention trials [0.03%]
糖尿病预防研究中NAVGATIOR试验受试者基线资料的比较分析
Henry Krum,John J V McMurray,Edward Horton et al.
Henry Krum et al.
The Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial is exploring two pharmacological strategies (nateglinide and valsartan, both alone and in combination) in the prevention of overt diabetes mellitus...
Randomized Controlled Trial
Cardiovascular therapeutics. 2010 Apr;28(2):124-32. DOI:10.1111/j.1755-5922.2010.00146.x 2010
Prevention of atrial fibrillation in cardiac surgery: time to consider a multimodality pharmacological approach [0.03%]
心脏手术中房颤预防：是时候考虑多模式药物方法了
Kwok M Ho,John P Lewis
Kwok M Ho
Atrial fibrillation (AF) is very common within the first 5 days of cardiac surgery. It is associated with significant morbidity including stroke, ventricular arrhythmias, myocardial infarction, heart failure, acute kidney injury, prolonged ...
The usefulness of chronic heart failure treatments in chronic cardiac graft failure [0.03%]
慢性心脏移植衰竭患者的心力衰竭治疗效果分析
Osman Najam,Nizar Yonan,Simon G Williams et al.
Osman Najam et al.
Following cardiac transplantation, registry data has demonstrated a gradual improvement in survival over the last several decades, which is testament to continual improvement in aftercare strategy. However, a significant number of patients ...
Jeremy A Schafer,Nicole K Kjesbo,Patrick P Gleason
Jeremy A Schafer
Atrial fibrillation (AF) is the most common sustained arrhythmia, affecting more than 2.2 million Americans. ACC/AHA/ESC guidelines for the management of patients with AF recommend amiodarone for maintaining sinus rhythm. Dronedarone is a d...