Lei Li,Xiaojian Song,Xiurui Ma et al.
Lei Li et al.
Ketone bodies can serve as energy substrates for the heart and perform important molecular signal transduction functions. In recent years, the therapeutic potential of ketone bodies has become a research hotspot in the field of cardiovascul...
FBXO38 Regulates Nox1 Stability to Reduce Vascular Endothelial Damage Induced by Low Oscillatory Shear Stress [0.03%]
FBXO38通过调控Nox1稳定性减轻低振荡切应力诱导的血管内皮细胞损伤
Wan-Li Yu,Li-Wen Deng,Huan-Huan Li et al.
Wan-Li Yu et al.
Oxidative stress and endothelial dysfunction are critical drivers of atherosclerosis, but the mechanisms regulating oxidative stress under disturbed flow conditions remain incompletely understood. The ubiquitin-proteasome system, particular...
Metabolic Profiling Reveals Diagnostic Biomarkers for Distinguishing Myocarditis From Acute Myocardial Infarction [0.03%]
代谢轮廓鉴别诊断心肌炎和急性心梗的生物标志物
Yuting Chen,Xiu Liu,Chengying Hong et al.
Yuting Chen et al.
Background: Distinguishing between myocarditis (MC) and acute myocardial infarction (AMI) in the early stages is crucial due to their similar symptoms yet vastly different treatment protocols. This study seeks to utilize metabolomics techni...
Comparative Study
Cardiovascular therapeutics. 2025 Apr 16:2025:6292099. DOI:10.1155/cdr/6292099 2025
Does Spontaneous Echo Contrast in the Left Atrial Appendage Increase Thromboembolism Risk After Left Atrial Appendage Closure? A Retrospective Study on Its Impact on Device-Related Thrombosis and Arterial Thromboembolic Events [0.03%]
左心耳自发性回声对比度增加经导管左心耳闭合术后装置相关血栓和动脉栓塞风险？一项回顾性研究其影响分析
Kandi Zhang,Hanwen Yu,Yihua Lu et al.
Kandi Zhang et al.
Background: Left atrial appendage closure (LAAC) prevents arterial thromboembolic events (ATEs) in nonvalvular atrial fibrillation (AF). Spontaneous echo contrast (SEC) is an independent risk factor for left atrial appendage (LAA) thrombosi...
The Association of P2Y12 Inhibitor Pretreatment With Length of Stay Among Patients With Acute Coronary Syndrome Who Underwent Coronary Artery Bypass Graft Surgery: A Cohort Study [0.03%]
P2Y12抑制剂术前用药与急性冠脉综合征冠状动脉旁路移植患者住院时间的关系：队列研究
Kramer J Wahlberg,Cyrus Thomas-Walker,Bradley J Tompkins et al.
Kramer J Wahlberg et al.
Introduction: Recent clinical practice guidelines do not recommend routine P2Y12 inhibitor pretreatment for patients with non-ST-elevation acute coronary syndromes (NSTE-ACS) treated with an early invasive strategy based upon clinical trial...
Thrombospondin-1 Silencing Ameliorates Osteoblastic Differentiation of Aortic Valve Interstitial Cells via Inhibiting Nuclear Factor- κ B Pathway [0.03%]
沉默血小板源性生长因子-1通过抑制核因子- κ B途径改善主动脉瓣间质细胞成骨分化
Qing Li,Chengxiang Song,Zisong Wei et al.
Qing Li et al.
Objective: Calcific aortic valve disease (CAVD) is a progressive cardiovascular condition driven by the osteogenic differentiation of valve interstitial cells (VICs), with no effective drug therapies currently available. Hence, our objectiv...
Clinical and Echocardiographic Risk Factors of Adverse Outcomes in Young Patients With Dilated Cardiomyopathy [0.03%]
年轻扩张型心肌病患者不良预后的临床及超声心动图预测因素分析
Mengwan Li,Wenheng Liu,Shouling Mi et al.
Mengwan Li et al.
Purpose: This study is aimed at identifying clinical and echocardiographic factors associated with all-cause mortality or heart transplantation (HTx) in young patients with dilated cardiomyopathy (DCM). Methods: We conducted a retrospective...
Cysteine-Rich Protein 61 (CCN1) Deficiency Alleviated Cardiac Remodeling in 5/6 Nephrectomized Mice by Suppressing the MAPK Signaling Pathway [0.03%]
半肾切除小鼠缺血性心脏重塑通过抑制MAPK信号传导途径受到胱抑素丰富蛋白61缺乏的缓解
Yihan Zhao,Liang Gu,Yunxuan Chen et al.
Yihan Zhao et al.
Background: With the progression of chronic kidney disease (CKD), we can often observe cardiac remodeling, fibrosis, and cardiac failure in patients. Cysteine-rich protein 61 (CCN1) is an extracellular matrix protein that plays a reuse role...
The Prognostic Significance of the DBIL/HDLC Ratio in Patients With Dilated Cardiomyopathy [0.03%]
德比林/高清卡比率在扩张型心肌病患者中的预后意义
Xinyi Wang,Qiqi Song,Qingqing Zhang et al.
Xinyi Wang et al.
Background: In cardiovascular pathology, both direct bilirubin (DBIL) and high-density lipoprotein cholesterol (HDLC) have been associated with adverse clinical outcomes. However, the prognostic significance of these biomarkers in the conte...
A Positive Feedback Loop Between CXCL16 and the Inflammatory Factors IL-17A and TGF- β Promotes Large Artery Atherosclerosis by Activating the STAT3/NF- κ B Pathway [0.03%]
CXCL16与炎性因子IL-17A和TGF-β的正反馈循环通过激活STAT3/NF-κB通路促进大动脉粥样硬化形成
Xuechen Cui,Yuan Wang,Xuening Li et al.
Xuechen Cui et al.
CXC chemokine ligand 16 (CXCL16) expression is often observed in studies related to atherosclerosis (AS). However, the process by which CXCL16 promotes AS is still unknown. CXCL16 has the potential to be a therapeutic target for atheroscler...