Is Carvedilol Effective in Preventing and Modulating Concentric Cardiac Remodelling? A Comprehensive Systematic Review and Meta-Analyses [0.03%]
卡维地洛防治同心性心室重构有效吗?系统评价和.meta.分析
Alice Valeria Wiyono,Azizah Puspitasari Ardinal
Alice Valeria Wiyono
Background: Carvedilol, commonly used to treat hypertension and known for its vasodilatory and pleiotropic effects, has been studied in various patient populations. However, its specific impact on diastolic dysfunction an...
Antiatherogenic and Cardioprotective Effects of a Xanthine Derivative KMUP-1 in ApoE Knockout Mice [0.03%]
KMUP-1(一种黄嘌呤衍生物)的抗动脉粥样硬化和心脏保护作用及机制研究
Erna Sulistyowati,Shang-En Huang,Chih-Chieh Hsu et al.
Erna Sulistyowati et al.
It is essential to manage cardiovascular disease related to atherosclerosis through understanding its disease progression mechanism. The effects of the xanthine derivative KMUP-1 on alleviating atherosclerosis and cardiac remodeling, as wel...
Hemodynamic Variability in Aortic Stenosis and Regurgitation During Transcatheter Aortic Valve Replacement With Self-Expanding Valves [0.03%]
经导管主动脉瓣置换术中自膨胀瓣膜治疗主动脉狭窄和反流的血动力学变异
Mingfei Li,Jianing Fan,Shasha Chen et al.
Mingfei Li et al.
Objective: This study investigated the impact of pathological differences between aortic stenosis (AS) and aortic regurgitation (AR) on hemodynamic outcomes following transcatheter aortic valve replacement (TAVR), with a ...
Comparative Study
Cardiovascular therapeutics. 2025 Oct 23:2025:8821435. DOI:10.1155/cdr/8821435 2025
The Impact of SGLT2 Inhibitors on Pulmonary Artery Pressures and Pulmonary Hemodynamics in Patients With Heart Failure: A Systematic Review [0.03%]
钠-葡萄糖协同转运蛋白-2抑制剂对心力衰竭患者肺动脉压和肺循环血流动力学影响的系统评价
Kritick Bhandari,Maria Qadri,Rochak Dhakal et al.
Kritick Bhandari et al.
Background: Heart failure is a major global health burden associated with high morbidity and mortality. Elevated pulmonary artery pressures (PAP) are linked to worse outcomes in heart failure patients. Sodium-glucose cotr...
Endovenous Laser Ablation of Insufficient Superficial Veins in Patients After Deep Vein Thrombosis Recanalisation [0.03%]
深静脉血栓再通患者的浅静脉腔内激光消融治疗
Srdjan Babic,Jovan Petrovic,Masa Petrovic et al.
Srdjan Babic et al.
Introduction: This study is aimed at investigating the safety of endovenous laser ablation treatment in the superficial venous system and perforator venous system in patients with previous deep vein thrombosis. ...
Single Fluoroscopy Versus Transesophageal Echocardiogram: A Comparative Evaluation for Left Atrial Appendage Occlusion With LACbes Device [0.03%]
单次透视与经食道超声对比评价左心耳封闭LACbes装置手术疗效
Mingfei Li,Dawei Lin,Lei Zhang et al.
Mingfei Li et al.
Objectives: This study was aimed at evaluating the effectiveness of fluoroscopy as an intraprocedural guidance method during left atrial appendage occlusion (LAAO) using the LACbes device. ...
Comparative Study
Cardiovascular therapeutics. 2025 Oct 12:2025:9933780. DOI:10.1155/cdr/9933780 2025
Optimization of Clinical Trial Design and Decision-Making for Heart Failure with Preserved Ejection Fraction (HFpEF): A Meta-Analysis Based on a Placebo Response Model [0.03%]
基于安慰剂反应模型的心力衰竭伴射血分数保留(HFpEF)临床试验设计与决策优化的 meta 分析
Xiaoya Chen,Juan Yang,Ling Xu et al.
Xiaoya Chen et al.
Objective: The aim of this study was to establish a placebo response model for efficacy indicators in heart failure with preserved ejection fraction (HFpEF) clinical trials, facilitating sample size estimation and trial o...
Metformin Attenuates Myocardial Ischemia-Reperfusion Injury in Rats by Modulating JNK Pathway and Inhibiting PANoptosis Mechanisms [0.03%]
二甲双胍通过调节JNK通路和抑制PANoptosis机制减轻大鼠心肌缺血再灌注损伤
Biao Hou,Xuejian Hou,Liyue Zhang et al.
Biao Hou et al.
Purpose: Myocardial ischemia-reperfusion injury (MIRI) is a condition in which the heart is aggravated when blood flow is restored after tissue damage caused by ischemia. Metformin (Met), a widely prescribed antidiabetic ...
HTR2B-Mediated Endothelial Protection: Modulating Ferroptosis via the PI3K/AKT Signaling Pathway in Atherosclerosis [0.03%]
HTR2B介导的内皮保护作用:通过PI3K/AKT信号通路调节动脉粥样硬化中铁死亡的作用
Delin Li,Hui Li,Quanwei Zhao et al.
Delin Li et al.
Objective: The current study is aimed at elucidating the mechanisms underlying the involvement of ferroptosis in atherosclerosis (AS) and exploring potential therapeutic targets. ...
"RotaTripsy" as State-of-the-Art Strategy for Coronary Artery Calcification: A Scoping Review [0.03%]
旋转磨削术治疗冠状动脉钙化最新技术的综述性研究:“RotaTripsy”亮相 coronary artery calcification-CAC冠状动脉粥样硬化-ASA
Tianxu Hao,Zhenchun Song,Jiechun Li et al.
Tianxu Hao et al.
Background: Recently, the combination of rotational atherectomy (RA) with intravascular lithotripsy (IVL), known as "RotaTripsy," has been employed in the treatment of coronary lesions with severe calcification. In this article, we provide ...