Hypermetabolism and Lipid Alterations Postburn: A Cardiovascular Perspective [0.03%]
烧伤后的高代谢及脂质改变：心血管视角
Mohammed AbuBaha,Ameer Awashra,Bara AbuBaha et al.
Mohammed AbuBaha et al.
Severe thermal burns involving ≥ 20% of total body surface area (TBSA) initiate a distinct, prolonged physiological cascade extending well beyond the acute phase. This dysregulated response features chronic hypermetabolism, lipid remodelin...
Potential Diagnostic and Therapeutic Uses of DPT in Acute Type A Aortic Dissection [0.03%]
DPT在急性A型主动脉夹层中的潜在诊断和治疗价值分析
Ting Wei,Xiaopeng Yang,Chao Shi
Ting Wei
Purpose: Acute Type A aortic dissection (ATAAD) is a catastrophic cardiovascular emergency with high mortality and few treatment options. Diagnostic biomarkers or targeted treatments remain in the rudimentary stage, compl...
Epiafzelechin, a Flavanol, Regulates Lipid Homeostasis Through Modulation of HMGCR, PCSK9, and PPAR- α: Mechanistic Insights and Therapeutic Implications [0.03%]
表儿茶素通过调节HMGCR，PCSK9和PPAR-α调控脂质稳态的机制及治疗意义
Saud O Alshammari,Nazifa Shahzad,Muhammad Nasir Hayat Malik et al.
Saud O Alshammari et al.
Hyperlipidemia remains a leading modifiable risk factor for cardiovascular morbidity and mortality. Statins are considered the cornerstone of treatment; however, their adverse effects and limited efficacy in certain patient populations nece...
Elevated Resting Heart Rate in Hospitalized Patients With Atrial Fibrillation Is Associated With Increased Cardiovascular Risk [0.03%]
房颤住院患者静息心率增快与心血管风险增加相关
Kangning Han,Xia Li,Biao Fu et al.
Kangning Han et al.
Background: Effective rate control is important in the management of atrial fibrillation (AF). However, the relationship between resting heart rate (RHR) and adverse outcomes in hospitalized patients remains uncertain. ...
Observational Study
Cardiovascular therapeutics. 2026 Jan 26:2026:2106637. DOI:10.1155/cdr/2106637 2026
Nonlinear and Age-Specific Associations Between Atherogenic Index of Plasma and Differential Cardiovascular Risk Profiles in US Adults [0.03%]
美国成年人中血浆致动脉粥样硬化指数与心血管风险的非线性及年龄特异性关联
Yuelin Hu,Xuli Chen,Yanchao Liu et al.
Yuelin Hu et al.
Background: The association between the atherogenic index of plasma (AIP) and different cardiovascular disease (CVD) outcomes remains insufficiently studied. ...
Comparative Study
Cardiovascular therapeutics. 2026 Jan 21:2026:6691842. DOI:10.1155/cdr/6691842 2026
The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta-Analysis and Trial Sequential Analysis [0.03%]
四种新型PCSK9单克隆抗体治疗高胆固醇血症患者有效性和安全性的系统评价及网络meta分析和序贯试验分析
Sihua Wang,Chenyu Li,Duncong Fan
Sihua Wang
Aim: This network meta-analysis (NMA) evaluated four novel proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies for hypercholesterolemia management, comparing their lipid-lowering efficacy and safet...
From the Liver to Heart in Nonalcoholic Fatty Liver Disease: Single-Cell and Serum Evidence for Cytokeratin 18 in Predicting Cardiovascular Risk [0.03%]
从非酒精性脂肪肝到心脏：细胞角蛋白18在单细胞和血清中的心血管风险预测作用
Hongjing Xu,Xiang Ma,Fengjuan Chen et al.
Hongjing Xu et al.
Background: This study is aimed at measuring the expression of serum cytokeratin 18 (CK18) in patients with nonalcoholic fatty liver disease (NAFLD) and at evaluating its ability to discriminate NAFLD patients with and wi...
Correlation Between ALDH2 Gene Polymorphism and Coronary Artery Disease in Patients With Atrial Fibrillation [0.03%]
心房颤动患者ALDH2基因多态性与冠状动脉疾病的相关性研究
Bo Zheng,Meiling Li,Peng Wang et al.
Bo Zheng et al.
Objectives: The objectives of this study is to investigate the correlation between genotype polymorphism of aldehyde dehydrogenase 2 (ALDH2) and coronary artery disease (CAD) in atrial fibrillation patients. ...
Aldehyde Dehydrogenase-2 Alleviates Septic Myocardial Injury by Inhibiting Caspase-11-Mediated Noncanonical Pyroptosis [0.03%]
醛脱氢酶-2通过抑制非经典性焦亡缓解脓毒症心肌损伤
Huan Liang,Yuying He,Yiren Wang et al.
Huan Liang et al.
Purpose: The purpose of this study is to investigate the role of aldehyde dehydrogenase-2 (ALDH2) in septic myocardial injury, focusing on noncanonical pyroptosis. ...
Efficacy and Safety of Olezarsen in Patients With Hypertriglyceridemia: A Meta-Analysis of Randomized Controlled Trials [0.03%]
奥扎尔塞治疗高甘油三酯血症的疗效和安全性：随机对照试验的 meta 分析
Kainat Feroz,Amna Parvez,Noor Ul Huda Ramzan et al.
Kainat Feroz et al.
Aims: Novel drugs that target apoC-III in lipoprotein metabolism to reduce plasma triglycerides are currently under development. Olezarsen, a drug similar to its predecessor, volanesorsen, is in Phase 3 trials. A meta-ana...