Aldehyde Dehydrogenase-2 Alleviates Septic Myocardial Injury by Inhibiting Caspase-11-Mediated Noncanonical Pyroptosis [0.03%]
醛脱氢酶-2通过抑制非经典性焦亡缓解脓毒症心肌损伤
Huan Liang,Yuying He,Yiren Wang et al.
Huan Liang et al.
Purpose: The purpose of this study is to investigate the role of aldehyde dehydrogenase-2 (ALDH2) in septic myocardial injury, focusing on noncanonical pyroptosis. ...
Efficacy and Safety of Olezarsen in Patients With Hypertriglyceridemia: A Meta-Analysis of Randomized Controlled Trials [0.03%]
奥扎尔塞治疗高甘油三酯血症的疗效和安全性：随机对照试验的 meta 分析
Kainat Feroz,Amna Parvez,Noor Ul Huda Ramzan et al.
Kainat Feroz et al.
Aims: Novel drugs that target apoC-III in lipoprotein metabolism to reduce plasma triglycerides are currently under development. Olezarsen, a drug similar to its predecessor, volanesorsen, is in Phase 3 trials. A meta-ana...
Low-Dose Mavacamten Initiation in Obstructive Hypertrophic Cardiomyopathy: A Real-World Study in China [0.03%]
小剂量 mavacamten 治疗梗阻性肥厚型心肌病：中国的真实世界研究
Wenlong Yang,Hui Shi,Rebecca Suchi Chang et al.
Wenlong Yang et al.
Aims: To evaluate the real-world efficacy and safety of low-dose (2.5 mg) mavacamten initiation in Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). ...
Observational Study
Cardiovascular therapeutics. 2026 Jan 14:2026:5690104. DOI:10.1155/cdr/5690104 2026
Subclinical Hypothyroidism as a Risk for Coronary Artery Bypass Grafting [0.03%]
亚临床甲状腺功能减退冠状动脉旁路移植术的风险因素
Ricardo Mendes Martins,Felipe José M Pittella,Beatriz C de Oliveira et al.
Ricardo Mendes Martins et al.
Background: The relationship between hypothyroidism and cardiovascular disease is well established. However, data on subclinical hypothyroidism (SH) and its impact on major adverse cardiovascular events (MACEs) and postop...
Epigenetic Regulation of ITGB7 Promotes Coronary Heart Disease via Immune and Metabolic Pathways: A Multimodal Mendelian Randomization Study [0.03%]
表观遗传调控ITGB7通过免疫和代谢通路促进冠心病的多模态孟德尔随机化研究
Junchi Guo,Fang Huang,Peihan Lu et al.
Junchi Guo et al.
Background: Coronary heart disease (CHD) is a leading cause of cardiovascular mortality worldwide, with its pathogenesis being complex and not yet fully understood. The rapid development of genomics, especially in epigene...
A Multicohort Machine Learning Framework to Predict Mortality in Elderly Patients With Heart Disease: Insights From HARLS, SHARE, and HRS [0.03%]
基于HARLS、SHARE和HRS的多层次机器学习框架预测心脏病老人死亡风险研究
Zhiqiang Yang,Xiaohong Zhang
Zhiqiang Yang
Background: Elderly patients with heart disease face elevated mortality risk, yet predictive models specifically tailored for this population across different global regions remain limited. Current mortality prediction to...
Multicenter Study
Cardiovascular therapeutics. 2026 Jan 2:2026:8040700. DOI:10.1155/cdr/8040700 2026
Drug-Coated Balloons Versus Other Percutaneous Coronary Intervention Strategies in De Novo Coronary Artery Disease: A Systematic Review, Meta-Analysis With Trial Sequential Analysis [0.03%]
药物涂层球囊与经皮冠状动脉介入治疗新发冠心病的疗效比较：系统评价和 meta 分析及试验序贯分析
Yue Yu,Yue Miao Jiao,Yang Li et al.
Yue Yu et al.
Background: Drug-coated balloons (DCBs) present a viable option distinct from drug-eluting stents (DESs) in addressing coronary artery disease (CAD), particularly when it comes to in-stent restenosis (ISR) scenarios. The ...
Knockdown of LncRNA CCAT1 Attenuates ox-LDL-Induced Inflammation in THP1-Derived Macrophages via the miR-296-3p/FOSL1 Axis [0.03%]
lncRNA CCAT1通过miR-296-3p/FOSL1轴促进THP1来源的巨噬细胞内皮氧化低密度脂蛋白诱导的炎症反应
Haiping Zhang,Feng Liu,Guihua Miao et al.
Haiping Zhang et al.
Macrophage-driven inflammation, induced by dysfunctional lipid metabolism, is a pivotal process in the pathogenesis of atherosclerosis (AS). While long noncoding RNAs (LncRNAs) are established regulators, the specific mechanisms governing t...
Impact of Hyperhomocysteinemia on Valve Calcification and Prognosis in Rheumatic Mitral Valve Surgery [0.03%]
同型半胱氨酸血症对风湿性二尖瓣手术患者瓣膜钙化和预后的影响
Songhao Jia,Peiyi Liu,Maozhou Wang et al.
Songhao Jia et al.
Objective: Hyperhomocysteinemia is a risk factor for cardiovascular disease, but its impact on valve disease is lacking in research. This study was aimed at investigating the impact of hyperhomocysteinemia on rheumatic mi...
Association Between the Naples Score and Recurrence in Patients With Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation [0.03%]
南京评分与房颤射频消融术后复发的关系研究
Zhen Wang,Yilin Qu,Hua Wang et al.
Zhen Wang et al.
Purpose: To explore the relationship between the Naples Score and the recurrence of atrial fibrillation (AF) following radiofrequency catheter ablation (RFCA) in patients. ...