The Effect of Vitamin D3 Injection Combined With High-Intensity Interval Training on Excessive Autophagy in the Heart Tissue of Type 2 Diabetes-Induced Rats: An Analysis of the mTOR-Beclin-1-Fyco-1-Cathepsin D Pathway [0.03%]
维生素D3注射联合高强度间歇训练对2型糖尿病大鼠心脏组织过度自噬的影响:mTOR-Beclin-1-Fyco-1-猫hepsin D通路分析
Hadi Golpasandi,Mohammad Rahman Rahimi
Hadi Golpasandi
Introduction: This study investigated the effect of vitamin D3 injection combined with high-intensity interval training on cell signaling pathways involved in excessive autophagy, specifically the mTOR (mechanistic target of rapamycin)-Becl...
Comprehensive Analysis Based on Genes Associated With Cuproptosis, Ferroptosis, and Pyroptosis for the Prediction of Diagnosis and Therapies in Coronary Artery Disease [0.03%]
基于铜死亡、铁死亡和焦亡相关基因的综合分析在冠心病诊断和治疗预测中的应用
Yongyi Zhang,Zhehan Guo,Renkui Lai et al.
Yongyi Zhang et al.
Coronary artery disease (CAD) is a complex condition influenced by genetic factors, lifestyle, and other risk factors that contribute to increased mortality. This study is aimed at evaluating the diagnostic potential of genes associated wit...
Urine Output as a Novel Predictor for In-Hospital Mortality in Acute Pulmonary Embolism Patients: Training With the MIMIC Database and Validation With Independent Cohort [0.03%]
尿量作为急性肺栓塞患者住院死亡率的新预测指标:利用MIMIC数据库进行训练和独立队列验证
Wenjia Ai,Fangfei Li,Qilin Yang et al.
Wenjia Ai et al.
Background: Identifying high-risk patients with acute pulmonary embolism is vital for improving disease prognosis. However, current guidelines and research on risk factors are insufficient to meet clinical needs. This study was aimed at exp...
Impacts of CD36 Variants on Plasma Lipid Levels and the Risk of Early-Onset Coronary Artery Disease: A Systematic Review and Meta-Analysis [0.03%]
CD36基因变异对血浆脂质水平和早发冠状动脉疾病风险的影响:系统评价和荟萃分析
Zhi Luo,Lingwei Lv
Zhi Luo
Background: Recent studies have indicated that cluster of differentiation 36 (CD36) is closely linked to dyslipidemia and early-onset coronary artery disease (EOCAD). This study is aimed at investigating the impacts of CD36 gene variants on...
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis [0.03%]
多种心血管疾病潜在药物靶点的探索——基于孟德尔随机化和共定位分析的蛋白质组范围研究
Maoxia Fan,Na Li,Libin Huang et al.
Maoxia Fan et al.
Background: Cardiovascular diseases (CVDs) encompass a group of diseases that affect the heart and/or blood vessels, making them the leading cause of global mortality. In our study, we performed proteome-wide Mendelian randomization (MR) an...
The Acute Effects of Motor Imagery Combined With Action Observation Breathing Exercise on Cardiorespiratory Responses, Brain Activity, and Cognition: A Randomized, Controlled Trial [0.03%]
运动想象结合动作观察呼吸训练对心肺反应,脑活动和认知的急性效应:一项随机对照试验
Ebrar Atak,Amine Ataç
Ebrar Atak
Breath and brain activity have been integral to daily life since time immemorial. Cognition and cardiorespiratory responses are closely interlinked, necessitating further investigation into their dynamics. The potential benefits of combinin...
Randomized Controlled Trial
Cardiovascular therapeutics. 2025 Feb 22:2025:6460951. DOI:10.1155/cdr/6460951 2025
Frontiers and Hotspot Evolution of NLRP3 Inflammasome in Myocardial Infarction Research: A Bibliometric Analysis From 2013 to 2024 [0.03%]
2013至2024年心肌梗死研究中NLRP3炎症小体的前沿与热点演化趋势:一项文献计量分析
Jin-Wen Wu,Qi Lan,Ding-Shan Zhang et al.
Jin-Wen Wu et al.
The NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an essential role in myocardial infarction (MI) development. Up to now, no bibliometric analyses of NLRP3 in MI have been performed. Publicatio...
Concomitant Atrial Fibrillation Radiofrequency Ablation During Total Thoracoscopic Valve Replacement: Safety, Early-Term Efficacy, and Predictors of Early Atrial Arrhythmia Recurrence [0.03%]
全胸腔镜下换瓣同时进行房颤射频消融:安全性、近期有效性和早期心律失常复发的预测因素
Zhiqin Lin,Zheng Xu,Liangwan Chen et al.
Zhiqin Lin et al.
Background: Atrial fibrillation (AF) complicates cardiac surgery, including valve replacements, increasing perioperative risk and impacting long-term outcomes. Concomitant radiofrequency ablation (RFA) during cardiac surgeries shows promise...
Observational Study
Cardiovascular therapeutics. 2025 Feb 17:2025:8872143. DOI:10.1155/cdr/8872143 2025
Efficacy and Safety of Stellate Ganglion Block for Treating Angina Pectoris: A Systematic Review and Meta-Analysis [0.03%]
星状神经节阻滞治疗心绞痛的有效性和安全性:系统评价和荟萃分析
Ying Wei,Jian Xiong,Xiao Li et al.
Ying Wei et al.
Purpose: This systematic review and meta-analysis of randomized controlled trials (RCTs) is aimed at assessing the clinical efficacy and safety of stellate ganglion block (SGB) for angina pectoris (AP). Methods: PubMed, Embase, Cochrane Lib...
Imperatorin's Effect on Myocardial Infarction Based on Network Pharmacology and Molecular Docking [0.03%]
基于网络药理学和分子对接法探讨帝皇丸防治心肌梗死的作用机制研究
Ruizhe Zhang,Peng Wang,Yao Jin et al.
Ruizhe Zhang et al.
Purpose: Myocardial infarction (MI), a severe cardiovascular disease, is the result of insufficient blood supply to the myocardium. Despite the improvements of conventional therapies, new approaches are needed to improve the outcome post-MI...