Systematic Pharmacology Combined With Experimental Validation Reveals the Apoptosis-Related Mechanism of Simiao Yong'an (SMYA) Decoction Against Myocardial Ischemia-Reperfusion Injury [0.03%]
Huanjie Fu,Eryue Liu,Hao Yu et al.
Huanjie Fu et al.
Background: According to traditional Chinese medicine theory, acute myocardial infarction (AMI) is primarily associated with qi stagnation and blood stasis. Simiao Yong'an (SMYA) decoction is a well-known prescription tha...
Safety and Feasibility of a Novel Split Design Left Atrial Appendage Occluder: From Preclinical Investigations to First-in-Human Application [0.03%]
一种新型左心耳夹层装置的设计、安全性和可行性：从临床前研究到首次人体应用
Mingfei Li,Dawei Lin,Lei Zhang et al.
Mingfei Li et al.
Objective: This study was designed to first evaluate the histological compatibility of the split occluder in preclinical animal models, followed by clinical validation of its procedural feasibility and occlusion effective...
Integrating Traditional Wisdom With Modern Science: Ginsenosides as Antiheart Failure Agents [0.03%]
传统智慧与现代科学的融合——人参皂苷抗心力衰竭研究进展
Li Zhou,Yanhua Li,Wenjie Yin et al.
Li Zhou et al.
Heart failure (HF), as the terminal stage of various cardiovascular diseases, remains a global health challenge with persistently high morbidity and mortality rates. Although current therapies-including angiotensin receptor-neprilysin inhib...
Association Between Albumin-Corrected Anion Gap and Mortality in ICU Patients With Acute Heart Failure: A MIMIC-IV Cohort Study [0.03%]
急性心力衰竭患者血清纠正性阴离子间隙与重症监护病房死亡率的相关性：一项MIMIC-IV队列研究
Huijuan Pu,Guoping Zhao,Yumin Wang et al.
Huijuan Pu et al.
Background: The albumin-corrected anion gap (ACAG) has been associated with adverse outcomes in critically ill patients. However, its prognostic value in patients with acute heart failure (AHF) remains unclear. This study...
Association of Initial Laxative Strategy With Clinical Outcomes in Critically Ill Patients With Acute Myocardial Infarction: A Retrospective Cohort Study [0.03%]
急性心肌梗死重症患者初始通便策略与临床结局的相关性：回顾性队列研究
Bingfu Wang,Yulong Song,Yujian Fan et al.
Bingfu Wang et al.
Background: Although laxatives are commonly used for constipation in critically ill patients with acute myocardial infarction (AMI), the optimal initial choice is unclear. We are aimed at comparing the clinical outcomes o...
Comparative Study
Cardiovascular therapeutics. 2026;2026(1):e1649836. DOI:10.1155/cdr/1649836 2026
The Association Between Sedentary Behavior and Cardiovascular Disease Risk: An Analysis Based on NHANES Data [0.03%]
基于NHANES数据的久坐行为与心血管疾病风险的相关性分析
Heming Huang,Zhe Zhao,Zemou Yu et al.
Heming Huang et al.
Background: Sedentary behavior has become a major global public health challenge and is closely associated with cardiovascular disease (CVD). Sedentary behavior not only increases the risk of various chronic diseases but ...
Effect of Statin Use on Mortality in Individuals With Cardiovascular-Kidney-Metabolic Syndrome: A Retrospective Propensity Score-Matched Cohort Study [0.03%]
他汀类药物使用对心血管-肾脏-代谢综合征个体死亡率影响的回顾性倾向分值匹配队列研究
Cheng Yuan,Yuguo Ge,Wenqi Ge et al.
Cheng Yuan et al.
Background: The present study is aimed at investigating the effects of statins on all-cause and cardiovascular mortalities in individuals with cardiovascular-kidney-metabolic syndrome (CKMS). ...
IL6/IL10/TLR4 Govern Immunogenic Cell Death in Aortic Dissection [0.03%]
白细胞介素6/白细胞介素10/ toll样受体4调控主动脉夹层免疫性细胞死亡
Yukui Du,Dongqing Chang,Bofeng Yu et al.
Yukui Du et al.
Background: Aortic dissection (AD), a life-threatening cardiovascular emergency, poses a significant threat to global cardiovascular health. Emerging evidence implicates programmed cell death (PCD) as a critical driver of...
Comparative Outcomes of Fractional Flow Reserve and Intravascular Ultrasound Guidance for Percutaneous Coronary Intervention in Intermediate Lesions: A Systematic Review and Meta-Analysis [0.03%]
基于中间病变冠状动脉介入治疗的血流储备分数与血管内超声对比研究系统评价和 meta 分析
Eyad Jamileh,Zuha Akhtar,Kanita Farooq et al.
Eyad Jamileh et al.
Objective: Advanced techniques beyond angiography increasingly guide percutaneous coronary intervention (PCI). Fractional flow reserve (FFR) and intravascular ultrasound (IVUS) are widely used for physiological and anatom...
Meta-Analysis
Cardiovascular therapeutics. 2026;2026(1):e6570642. DOI:10.1155/cdr/6570642 2026
Ginsenoside Rb1 Mitigates Myocardial Fibrosis Through Inhibiting Exosomal-Derived miRNA-21-Associated Inflammation and Cardiac Signaling [0.03%]
人参皂苷Rb1通过抑制外泌体携带的miRNA-21相关的炎症和心脏信号通路缓解心肌纤维化
Shihua Wang,Weifeng Chi,Yinghong Lu et al.
Shihua Wang et al.
Myocardial fibrosis exemplifies a crucial pathological event in the escalation of heart failure. Natural bioactive agents that can modulate and mitigate myocardial fibrosis hold promising potential as key therapeutic and preventive strategi...