Antipsychotic drugs are licensed as treatment for schizophrenia and other mental health disorders but can cause a range of unwanted effects that require close monitoring by, and close collaboration between, healthcare professionals across a...
Dabigatran etexilate (Pradaxa - Boehringer Ingelheim) is an oral anticoagulant that has been licensed in the EU since 2008 for thromboprophylaxis in adults following a hip or knee joint replacement. The marketing authorisation for the drug ...
Preterm birth (delivery before 37 weeks' gestation) is the commonest cause of neonatal mortality and morbidity in developed countries. Most of these births occur after spontaneous preterm labour. Intrauterine infection (often subclinical) i...
Helicobacter pylori eradication therapy helps to prevent recurrence of, and re-bleeding from, gastric and duodenal ulcers. It also causes regression of most localised gastric mucosa-associated lymphoid-tissue (MALT) lymphomas. Standard trip...
▾Prucalopride (Resolor - Shire Pharmaceuticals Ltd) is licensed, only in women, for symptomatic treatment of chronic constipation when laxatives fail to provide adequate relief. It is promoted as being "effective in helping to restore norm...
In 2009, around 86,500 people in the UK had HIV infection, of whom around a quarter were unaware of their condition. Of adults diagnosed in that year, around half were already at a late stage of disease (with a CD4 count below 350 cells/μL...
Drug and Therapeutics Bulletin
Drug and Therapeutics Bulletin
Systemic lupus erythematosus (SLE) is a complex multisystem autoimmune disease with a relapsing and remitting course.1 In the UK, the prevalence has been estimated as 25 per 100,000, and the annual incidence as 5.3 for females and 0.7 for m...