Frank Weber
Frank Weber
Neonates are both capable of experiencing pain and memory formation, albeit implicit memory. During surgical procedures, insufficient ablation of the stress response and possible implicit memory formation of intra-operative events might res...
Neonatal resuscitation [0.03%]
新生儿复苏术
Michael Clifford,Rodney W Hunt
Michael Clifford
Neonatal resuscitation techniques are evolving. More sophisticated methods of monitoring have emerged and current practices have been challenged. It is recognised that most newborns will require only gentle assistance to facilitate the tran...
Joseph R Tobin
Joseph R Tobin
Neonates are frequently not studied in the development of a novel pharmacological agent. With lack of data to support safe and effective use of a new agent in this population, sponsors will not receive approval for labelling the agent for u...
The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns [0.03%]
围术期对神经认知发育影响的药理学关注点
George K Istaphanous,Christopher G Ward,Andreas W Loepke
George K Istaphanous
Mounting evidence from animal studies has implicated that all commonly used anaesthetics and sedatives may induce widespread neuronal cell death and result in long-term neurological abnormalities. These findings have led to serious question...
Brian J Anderson,Karel Allegaert
Brian J Anderson
Neonatal anaesthesia dosing needs to be based on physiological characteristics of the newborn, pharmacokinetic/pharmacodynamic considerations and the adverse effects profile. Disease processes and treatments in this group are distinct from ...
Thierry Detaille,Thierry Pirotte,Francis Veyckemans
Thierry Detaille
Up to recently, inserting venous or arterial 'lines' in the neonate was essentially based on clinical skill and experience. The recent advent of portable ultrasound (US) machines with paediatric probes has resulted in the development of new...
Graham Kinottenbelt,Adam Skinner,Christian Seefelder
Graham Kinottenbelt
Tracheo-oesophageal fistula (TOF) and oesophageal atresia (OA) represent a series of anatomical abnormalities presenting for emergency surgery in the neonatal period. They present the anaesthetist with cardio-respiratory challenges in the p...
Stephen A Stayer,Yang Liu
Stephen A Stayer
Pulmonary hypertension presenting in the neonatal period can be due to congenital heart malformations (most commonly associated with obstruction to pulmonary venous drainage), high output cardiac failure from large arteriovenous malformatio...
Neonatal fluid management [0.03%]
新生儿液体管理
Isabelle Murat,Alexis Humblot,Laure Girault et al.
Isabelle Murat et al.
Perioperative fluid management in paediatrics has been the subject of many controversies in recent years, but fluid management in the neonatal period has not been considered in most reviews and guidelines. The literature regarding neonatal ...