Dose-response relationships between dairy intake and chronic metabolic diseases in a Chinese population [0.03%]
中国人群中乳制品摄入量与慢性代谢性疾病剂量反应关系的前瞻性研究
Panpan Guo,Henan Zhu,Hongzhi Pan et al.
Panpan Guo et al.
Background: This study investigated associations between dairy intake and chronic metabolic diseases (CMDs), and evaluated possible dose-response relationships in Chinese. ...
Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study [0.03%]
利拉鲁肽在丹麦的临床应用特点及降糖药物利用情况：一项基于常规医疗环境下的处方研究
Jakob S Knudsen,Reimar W Thomsen,Anton Pottegård et al.
Jakob S Knudsen et al.
Highlights This population-based real-world prescription study characterized all new users of liraglutide in northern Denmark from 2009 to 2015. More than half (57%) the patients had liraglutide prescribed as part of drug combinations outsi...
Diabetes news [0.03%]
糖尿病消息
Martin J Kurian,Peter J Rentzepis,Ann M Carracher et al.
Martin J Kurian et al.
Martin J. Kurian, Peter J. Rentzepis, Ann M. Carracher, and Kelly L. Close are of Close Concerns (http://www.closeconcerns.com), a healthcare information company focused exclusively on diabetes and obesity care. Close Concerns publishes Clo...
"Adjusting internal organs and dredging channel" electroacupuncture treatment prevents the development of diabetic peripheral neuropathy by downregulating glucose-related protein 78 (GRP78) and caspase-12 in streptozotocin-diabetic rats [0.03%]
调经导滞电针通过下调葡萄糖相关蛋白78和半胱氨酸糜酶-12防止链脲佐菌素糖尿病大鼠向糖尿病神经病变发展
Hong Pan,Haipeng Huang,Liying Zhang et al.
Hong Pan et al.
Background: The clinical efficacy of electroacupuncture in treating diabetic peripheral neuropathy (DPN) is significant, but the underlying mechanism of action is not clear. Considering that glucose-regulated protein 78 (...
Current understanding of the role of gut dysbiosis in type 1 diabetes [0.03%]
目前关于肠道菌群失调在1型糖尿病发病机制中作用的认识
Ahmed M Abdellatif,Nora E Sarvetnick
Ahmed M Abdellatif
Type 1 diabetes (T1D) is a chronic autoimmune disorder that results from destruction of the insulin-producing pancreatic β-cells. The disease mainly affects juveniles. Changes in the composition of the gut microbiota (dysbiosis) and change...
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux [0.03%]
抑制高迁移率族蛋白箱1(HMGB1)通过调节自噬流量来减轻足细胞凋亡和上皮间质转化
Juan Jin,Jianguang Gong,Li Zhao et al.
Juan Jin et al.
Background: Podocyte injury, characterized by podocyte hypertrophy, apoptosis, and epithelial-mesenchymal transition (EMT), is the major causative factor of diabetic nephropathy (DN). Autophagy dysfunction is regarded as ...
Anoop Misra,Hema Gopalan,Ranil Jayawardena et al.
Anoop Misra et al.
There has been a rapid escalation of type 2 diabetes (T2D) in developing countries, with varied prevalence according to rural vs urban habitat and degree of urbanization. Some ethnic groups (eg, South Asians, other Asians, and Africans), de...
Prognosis for residual islet β-cell secretion function in young patients with newly diagnosed type 1 diabetes [0.03%]
新诊断的年轻1型糖尿病患者的残存胰岛β细胞分泌功能结局预测因素分析
Haitao Miao,Juanjuan Zhang,Bin Gu et al.
Haitao Miao et al.
Background: This study investigated possible predictors of residual islet β-cell function (RBF) in young patients with newly diagnosed type 1 diabetes (T1D). ...
Mayer B Davidson
Mayer B Davidson
Highlights Since the PK/PD of U-500 regular insulin more closely resembles that of NPH insulin, it is commonly given before breakfast and dinner. However, a delayed response in which the major effect of the concentrated insulin takes place ...
Zachary Bloomgarden
Zachary Bloomgarden