Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy [0.03%]
纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用
Zijing Huang,Wai Kit Chu,Tsz Kin Ng et al.
Zijing Huang et al.
Aims: Diabetic retinopathy (DR) is a significant global public health concern. Alternative, safe, and cost-effective pharmacologic approaches are warranted. We aimed to investigate the therapeutic potential of nattokinase...
A comparative study of the gut microbiome in Indian children with type 1 diabetes and healthy controls [0.03%]
印度1型糖尿病儿童与健康儿童肠道微生物组的比较研究
Vaishali Tamahane,Shivang Bhanushali,Nikhil Shah et al.
Vaishali Tamahane et al.
Introduction: Type 1 diabetes mellitus (T1DM) occurs in genetically susceptible individuals due to certain environmental triggers causing destruction of insulin secreting beta cells. One of the environmental triggers stud...
Comparative Study
Journal of diabetes. 2024 May;16(5):e13438. DOI:10.1111/1753-0407.13438 2024
Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study [0.03%]
糖尿病血压控制目标（BPROAD）研究的目的和设计
BPROAD Study Group
BPROAD Study Group
Background: Diabetes and hypertension are major modifiable risk factors for cardiovascular disease. Previous clinical trials have demonstrated that intensive blood pressure reduction lowers the risk of cardiovascular dise...
Randomized Controlled Trial
Journal of diabetes. 2023 Dec;15(12):1029-1040. DOI:10.1111/1753-0407.13411 2023
Impact on glucometric variables and quality of life of the advanced hybrid closed-loop system in pediatric and adolescent type 1 diabetes [0.03%]
高级混合闭环系统对儿童和青少年1型糖尿病血糖指标及生活质量的影响
Alfonso Lendínez-Jurado,Ana Gómez-Perea,Ana B Ariza-Jiménez et al.
Alfonso Lendínez-Jurado et al.
Background: In recent years, technological advances in the field of diabetes have revolutionized the management, prognosis, and quality of life of diabetes patients and their environment. The aim of our study was to evalu...
Mohammad Reza Afsharmanesh,Zeinab Mohammadi,Azad Reza Mansourian et al.
Mohammad Reza Afsharmanesh et al.
Type 2 diabetes mellitus (T2DM) and its associated complications have become a crucial public health concern in the world. According to the literature, chronic inflammation and the progression of T2DM have a close relationship. Accumulated ...
Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population-based study [0.03%]
糖尿病患者血液生物标志物与动脉僵硬的关联：基于人口的队列研究
Yong-Qi Liang,Rui Zhou,Hao-Wen Chen et al.
Yong-Qi Liang et al.
Background: Arterial stiffness contributes to additional cardiovascular risks in diabetic patients by triggering the loss of vascular and myocardial compliance and promoting endothelial dysfunction. Thus, prevention of ar...
Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels [0.03%]
谷氨酸水平升高与血浆酶原水平升高有关
Hyo Jung Lee,Jeong Won Yeom,Ji Ho Yun et al.
Hyo Jung Lee et al.
Background: Glutamate is a major neurotransmitter, although it causes cytotoxicity and inflammation in nonneuronal organs. This study aimed to investigate the metabolic disorders in which glutamate, associated with type 2...
A diabetes update [0.03%]
糖尿病研究新进展
Zachary Bloomgarden
Zachary Bloomgarden
The effects of daily dose and treatment duration of metformin on the prevalence of vitamin B12 deficiency and peripheral neuropathy in Chinese patients with type 2 diabetes mellitus: A multicenter cross-sectional study [0.03%]
二甲双胍不同用法对中国2型糖尿病患者维生素B12缺乏及周围神经病变的影响：一项多中心横断面研究
Leili Gao,Xingwu Ran,Xuejun Liu et al.
Leili Gao et al.
Aims: To evaluate the prevalence of vitamin B12 deficiency in Chinese patients with type 2 diabetes mellitus receiving metformin treatment and to investigate the effects of metformin daily dose and treatment duration on t...
Multicenter Study
Journal of diabetes. 2023 Sep;15(9):765-776. DOI:10.1111/1753-0407.13428 2023
HLA-DR3 mediated CD4 T cell response against GAD65 in type 1 diabetes patients [0.03%]
HLA-DR3介导的1型糖尿病患者GAD65特异性的CD4 T细胞免疫反应
Neihenuo Chuzho,Neetu Mishra,Nikhil Tandon et al.
Neihenuo Chuzho et al.
Aim: We planned this study to identify diabetogenic glutamic acid decarboxylase (GAD65) peptides possibly responsible for human leucocyte antigen (HLA)-DR3/DQ2-mediated activation of GAD65-specific CD4 T cells in type 1 d...