Plasma mitochondrial DNA is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus [0.03%]
孕早期母体血浆线粒体DNA水平升高可能成为妊娠期糖尿病的预测标志物
Dushyant Kumar Sahu,Jessy Abraham
Dushyant Kumar Sahu
Background: We evaluated whether an abundance of first-trimester plasma mitochondrial DNA (mtDNA) fragments could predict the risk for the development of gestational diabetes mellitus (GDM) by the late second or early thi...
A network meta-analysis of association between cardiometabolic risk factors and COVID-19 outcome severity [0.03%]
一项网络meta分析：心血管代谢危险因素与新冠肺炎病情严重程度之间的关联性分析
Alina Binbin Li,Bo Yang,Yufei Li et al.
Alina Binbin Li et al.
Background: Cardiometabolic comorbidities have been associated with a higher risk of COVID-19 severity and mortality, but more investigations are needed to determine which comorbidity is more detrimental. ...
Meta-Analysis
Journal of diabetes. 2023 Nov;15(11):968-977. DOI:10.1111/1753-0407.13445 2023
Cardiometabolic profile of women with a history of overt diabetes compared to gestational diabetes and normoglycemia in index pregnancy: Results from CHIP-F study [0.03%]
CHIP-F研究中既往患有显性糖尿病的妇女与妊娠糖尿病和正常糖耐量孕妇的心血管代谢特征对比研究报告
Yashdeep Gupta,Alpesh Goyal,Samita Ambekar et al.
Yashdeep Gupta et al.
Purpose: We aimed to evaluate the prevalence of postpartum diabetes among women with a history of overt diabetes in pregnancy (ODiP) and compare with women having a history of gestational diabetes mellitus (GDM) and normo...
Comparative Study
Journal of diabetes. 2024 May;16(5):e13461. DOI:10.1111/1753-0407.13461 2024
IFN-γ enhances the therapeutic efficacy of MSCs-derived exosome via miR-126-3p in diabetic wound healing by targeting SPRED1 [0.03%]
干扰素γ通过miR-126-3p靶向SPRED1增强间充质干细胞来源的外泌体在糖尿病创面修复中的治疗效果
Wen Lu,Xuan Du,Shengyi Zou et al.
Wen Lu et al.
Background and aims: The traditional treatment of diabetic wounds is unsatisfactory. Exosomes isolated from bone marrow mesenchymal stem cells (BMSCs) promote the healing of diabetic wounds. However, whether the exosomes ...
Transferrin receptor levels and its rare variant are associated with human obesity [0.03%]
转铁蛋白受体水平及其罕见变异与人类肥胖相关
Jin Qiu,Zhiyin Zhang,Yepeng Hu et al.
Jin Qiu et al.
Aim: Iron homeostasis is critical for functional respiratory chain complex of mitochondrial, thus potentially contributing to fat biology and energy homeostasis. Transferrin receptor (Tfrc) binds to transferrin for extrac...
The link between obesity and insulin resistance among children: Effects of key metabolites [0.03%]
儿童肥胖与胰岛素抵抗之间的联系：关键代谢物的影响
Wu Yan,Su Wu,Qianqi Liu et al.
Wu Yan et al.
Background: Childhood obesity became a severe public health challenge, and insulin resistance (IR) was one of the common complications. Both obesity and IR were considered as the basis of metabolic disorders. However, it ...
Associations between handgrip strength and skeletal muscle mass with all-cause mortality and cardiovascular mortality in people with type 2 diabetes: A prospective cohort study of the UK Biobank [0.03%]
握力和骨骼肌量与2型糖尿病患者全因死亡率和心血管疾病死亡率的相关性：英国生物样本库的前瞻性队列研究
Lingqi Wei,Jingjing Zeng,Menglin Fan et al.
Lingqi Wei et al.
Aims: To explore the associations between handgrip strength (HGS) and skeletal muscle mass (SMM) with all-cause and cardiovascular disease (CVD) mortality risk in type 2 diabetes (T2DM) patients. ...
Fatty acid β-oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice [0.03%]
胰高血糖素受体拮抗通过促进脂肪酸β氧化和线粒体融合发挥心肌微血管内皮细胞保护作用
Peng Wang,Rui Wei,Xiaona Cui et al.
Peng Wang et al.
Introduction: The role of cardiac microvascular endothelial cells (CMECs) in diabetic cardiomyopathy is not fully understood. We aimed to investigate whether a glucagon receptor (GCGR) monoclonal antibody (mAb) ameliorate...
Decreased in n-3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction [0.03%]
糖尿病合并心功能障碍患者DHA富集的小细胞外囊泡减少
Wei Ding,Xuejuan Zhang,Dandan Xiao et al.
Wei Ding et al.
Purpose: Diabetic cardiomyopathy is the leading cause of death in diabetic patients, and the mechanism by which factors other than hyperglycemia contribute to the development of diabetic cardiomyopathy is unknown. Serum s...
Diabesity phenotype in relation to the incidence and resolution of nonalcoholic fatty liver disease: A prospective cohort study [0.03%]
与非酒精性脂肪肝病的发病率和缓解相关的糖尿病肥胖表型：前瞻性队列研究
Lijie Kong,Chaojie Ye,Yiying Wang et al.
Lijie Kong et al.
Background: Diabesity is a term used to emphasize the dual epidemic and the combined detrimental effects of diabetes and obesity. We aimed to investigate the associations of diabesity with the incidence and resolution of ...