Raised natriuretic peptides, big-endothelin-1 and improved beta-cell function in type 2 diabetic males with hyperuricaemia [0.03%]
高尿酸血症Ⅱ型糖尿病男性患者脑利钠肽、大内皮素-1及β细胞功能改善
Michel P Hermans,Sylvie A Ahn,Michel F Rousseau
Michel P Hermans
Urate, a naturally-occurring antioxidant, is a marker/factor for cardiovascular disease. Hyperuricaemia is associated with IR, MetS and endothelial dysfunction. We characterised the associations between neurohormones, uricaemia, and glucose...
Kunihiko Aizawa,J Kevin Shoemaker,Tom J Overend et al.
Kunihiko Aizawa et al.
We evaluated (1) endothelial function (FMD, ICAM-1 and VCAM-1) cross-sectionally in subjects with (MS+) and without (MS-) metabolic syndrome who were at increased risk for cardiovascular disease due to either HNBP and/or IGR, and (2) examin...
Review article: Diabetes mellitus and heart failure--an overview of epidemiology and management [0.03%]
糖尿病与心力衰竭——流行病学及治疗概述
V Baliga,R Sapsford
V Baliga
Heart failure and diabetes mellitus are chronic complex medical conditions that are closely related and commonly coexist.Treatment options have varied over the years, but newer treatment modalities have developed which have improved prognos...
Review article: Left ventricular dysfunction and heart failure in metabolic syndrome and diabetes without overt coronary artery disease--do we need to screen our patients? [0.03%]
评述：代谢综合征与糖尿病患者的心力衰竭和左心室功能障碍——对无明显冠状动脉疾病的患者进行筛查有必要吗？
Aled W Roberts,Andrew L Clark,Klaus K Witte
Aled W Roberts
The metabolic syndrome and its components, glucose intolerance, T2DM, hypertension, dyslipidaemia and obesity are increasingly common. Patients with the metabolic syndrome have a higher prevalence of chronic heart failure (CHF) and, once di...
Parminder S Chaggar,Steven M Shaw,Simon G Williams
Parminder S Chaggar
DM is an independent risk factor for the development of HF and its presence confers an adverse prognosis for those already diagnosed with HF.TZDs are potent insulin-sensitisers associated with a number of beneficial cardiovascular effects. ...
Mark T Kearney
Mark T Kearney
Maarten de Mulder,Victor A W M Umans
Maarten de Mulder
Coadministration of muraglitazar plus glyburide: improvement of glycaemic and lipid profiles in patients with type 2 diabetes [0.03%]
莫格列扎坦联合格列本脲治疗2型糖尿病患者可改善患者的血糖和血脂水平
Cindy J Rubin,Veerle De Pril,Fred T Fiedorek
Cindy J Rubin
In this trial we evaluated the efficacy and safety of muraglitazar, a dual (alpha/gamma) peroxisome proliferator-activated receptor activator, plus glyburide in patients with type 2 diabetes not controlled with sulphonylurea monotherapy. Af...
Long-term effect of metformin on metabolic parameters in the polycystic ovary syndrome [0.03%]
二甲双胍对多囊卵巢综合征患者长期代谢指标的影响
Kai I Cheang,Jessica M Huszar,Al M Best et al.
Kai I Cheang et al.
Insulin resistance is a central feature of the PCOS and may increase cardiovascular risk. Owing to insulin resistance, the metabolic syndrome is more prevalent in women with PCOS compared with unaffected women. Metformin improves the metabo...