The BARI 2D study: a randomised trial of therapies for type 2 diabetes and coronary artery disease [0.03%]
BARI 2D研究:2型糖尿病并冠状动脉疾病患者治疗方案的随机对照试验
Martin K Rutter,Richard W Nesto
Martin K Rutter
The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial randomized 2368 patients with type 2 diabetes (T2DM) and coronary artery disease to either prompt revascularization or intensive medical therapy alone; and to...
Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population [0.03%]
卡帕辛10基因的危险型和保护型基因在印度东部2型糖尿病患者中的共存现象
Sangeeta Adak,Sanghamitra Sengupta,Subhankar Chowdhury et al.
Sangeeta Adak et al.
Linkage and association studies have detected a role for Calpain-10 (CAPN10) polymorphisms in susceptibility to T2DM in many populations. This study aimed to evaluate possible associations between three SNPs in the CAPN10 (UCSNPs -43, -19 a...
The PPARgamma Pro12Ala variant is associated with insulin sensitivity in Russian normoglycaemic and type 2 diabetic subjects [0.03%]
PPARγ的Pro12Ala变异体与俄罗斯正常血糖和2型糖尿病受试者的胰岛素敏感性有关
Dimitry A Chistiakov,Viktor A Potapov,Dmitry S Khodirev et al.
Dimitry A Chistiakov et al.
The second isoform of the PPARgamma2 is specific for adipose tissue. In adipocytes, this isoform is involved in the regulation of adipogenesis and lipid storage, insulin and glucose metabolism. Pro12Ala, a missense mutation in exon 2 of PPA...
Lipoprotein-associated phospholipase A2, C-reactive protein, and coronary artery disease in individuals with type 1 diabetes and macroalbuminuria [0.03%]
与1型糖尿病和大量白蛋白尿相关的载脂蛋白相关磷脂酶A2、C反应蛋白及冠状动脉疾病
Rachel G Miller,Tina Costacou,Trevor J Orchard
Rachel G Miller
Given the paucity of data in type 1 diabetes concerning lipoprotein-associated phospholipase A( 2) (Lp-PLA(2)), we examined its prospective relationship with coronary artery disease (CAD), as well as the effect of modification by C-reactive...
Hairong Nan,Zengchang Pang,Shaojie Wang et al.
Hairong Nan et al.
The objective of this study was to investigate the association of serum UA with either FPG or 2hPG levels among Chinese adults in Qingdao, China. A population-based survey for diabetes was performed in 2006 in Qingdao. The survey included 1...
Metabolic syndrome, aging, physical inactivity, and incidence of type 2 diabetes in general African population [0.03%]
代谢综合征、衰老、运动缺乏和一般非洲人群2型糖尿病的发病危险关系研究
B Longo-Mbenza,J B Kasiam Lasi Onkin,A Nge Okwe et al.
B Longo-Mbenza et al.
The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at...
Pioglitazone improves superoxide dismutase mediated vascular reactivity in the obese Zucker rat [0.03%]
吡格列酮改善肥胖佐克_rat的超氧化物歧化酶介导的血管反应性
Amir H Dorafshar,Kogie Moodley,Michelle Khoe et al.
Amir H Dorafshar et al.
Objective: To test the hypothesis that the thiazolidinedione agent, pioglitazone, mediates its chronic BP lowering action via improving vascular reactivity. ...
Diabetes mellitus is associated with plaque classified as thin cap fibroatheroma: an intravascular ultrasound study [0.03%]
糖尿病与易损斑块:一项血管内超声研究
Steven P Marso,John A House,Volker Klauss et al.
Steven P Marso et al.
We compared measures of ID coronary atherosclerosis between diabetic and non-diabetic patients enrolled in a prospective multinational IVUS registry. The region of interest was the most diseased 10 mm segment of a single coronary artery. Co...
Type 2 diabetic patients with resistant hypertension should be screened for primary aldosteronism [0.03%]
糖尿病伴原发性醛固酮增多症抵抗高血压患者的筛查
J J Mukherjee,C M Khoo,A C Thai et al.
J J Mukherjee et al.
BP control in diabetic patients is often poor. The contribution of secondary hypertension due to undiagnosed PA in hypertensive type 2 diabetic patients is not well studied. We prospectively screened 100 consecutive Asian type 2 diabetic pa...
P J Grant
P J Grant