Rapid effect of single-dose rosiglitazone treatment on endothelial function in healthy men with normal glucose tolerance: data from a randomised, placebo-controlled, double-blind study [0.03%]
罗格列酮单次剂量治疗对正常血糖水平健康男性内皮功能的快速影响:一项随机、双盲、安慰剂对照研究的数据分析
Thomas Walcher,Daniel Walcher,Jürgen Hetzel et al.
Thomas Walcher et al.
Antidiabetic thiazolidinediones (TZDs) improve endothelial function in patients with or without type 2 diabetes. The present randomised, placebo-controlled, double-blind study examined the time course of a single dose of rosiglitazone on fl...
Randomized Controlled Trial
Diabetes & vascular disease research. 2010 Jul;7(3):178-85. DOI:10.1177/1479164110367812 2010
CCAAT/enhancer binding protein alpha, beta and delta gene variants: associations with obesity related phenotypes in the Leeds Family Study [0.03%]
CCAAT/增强子结合蛋白α、β和δ基因多态性与利兹家族研究中肥胖相关表型的关联分析
Claire E Bennett,Jérémie Nsengimana,Jacqueline A Bostock et al.
Claire E Bennett et al.
Objective: To identify novel polymorphisms in the genes encoding the transcription factors CCAAT/enhancer binding protein alpha, beta and delta ( CEBPA, CEBPB, CEBPD) and investigate associations between polymorphisms and...
Adherence to vascular protection drugs in diabetic patients in Quebec: a population-based analysis [0.03%]
魁北克糖尿病患者使用血管保护药物的依从性:基于人群的分析
Shabnam Asghari,Josiane Courteau,Catherine Drouin et al.
Shabnam Asghari et al.
The purpose of this study was to assess adherence to vascular protection drugs in diabetic patients using a cohort of diabetic patients aged >or=30 years, covered by the public drug insurance in the province of Quebec, excluding gestational...
Early stage detection of conduit artery endothelial dysfunction in patients with type 1 diabetes [0.03%]
1型糖尿病患者血管内皮功能障碍的早期检测
Jeremy Bellien,Agathe Costentin,Benedicte Dutheil-Maillochaud et al.
Jeremy Bellien et al.
Flow-mediated dilatation evaluation using hand skin heating may possibly be more accurate than post-ischaemic hyperaemia to detect conduit artery endothelial dysfunction in type 1 diabetes. We measured in 24 type 1 diabetic patients (n=16 w...
Comparison between surrogate indices of insulin sensitivity and resistance, and the hyperinsulinaemic euglycaemic glucose clamp in urban South African blacks with and without coronary artery disease [0.03%]
血糖钳技术与胰岛素抵抗和耐受替代指标在有无冠心病的南非城市黑人中的比较研究
Lucas Ntyintyane,Vanessa Panz,Frederick Raal et al.
Lucas Ntyintyane et al.
Coronary artery disease (CAD) and diabetes mellitus (DM) are increasing in urban black South Africans during their transition from a rural to a western lifestyle. Insulin resistance is associated with CAD and DM. Fasting-based indices [home...
Increased prevalence of cardiovascular disease and risk biomarkers in patients with unknown type 2 diabetes visiting cardiology specialists: results from the DIASPORA study [0.03%]
DIASPORA研究:心血管病及其危险因素在未知型2糖尿病心脏病患者中的高发性
Thomas Schöndorf,Georg Lübben,Efstrathios Karagiannis et al.
Thomas Schöndorf et al.
Background: Patients with diabetes mellitus and IGT have a high risk for cardiovascular events. It is tempting to speculate that these patients are often first seen by cardiologists. ...
Multicenter Study
Diabetes & vascular disease research. 2010 Apr;7(2):145-50. DOI:10.1177/1479164109358241 2010
The synthetic GLP-I receptor agonist, exenatide, reduces intimal hyperplasia in insulin resistant rats [0.03%]
合成GLP-1受体激动剂 Exenatide 对糖尿病抵抗型大鼠的内膜增生有抑制作用
Subramanyam N Murthy,Rose-Claire St Hilaire,David B Casey et al.
Subramanyam N Murthy et al.
We studied the effect of a synthetic GLP-1 receptor agonist, exenatide, a drug approved for the treatment of type 2 diabetes, on the recovery from vascular injury in Zucker (non-diabetic) fatty rats. Exenatide 5.0 microg/kg per day or salin...
Acute glucose dysmetabolism in the early phase of ST-elevation myocardial infarction: the age response [0.03%]
急性ST段抬高性心肌梗死早期糖代谢异常的年龄反应特征
Chiara Lazzeri,Serafina Valente,Marco Chiostri et al.
Chiara Lazzeri et al.
In elderly patients with AMI, hyperglycaemia is associated with increased mortality. Recently it has been observed that insulin resistance, as assessed by the HOMA index, proved an independent predictor of in-hospital mortality. The interac...
The effect of intensive glucose control on all-cause and cardiovascular mortality, myocardial infarction and stroke in persons with type 2 diabetes mellitus: a systematic review and meta-analysis [0.03%]
强化血糖控制对2型糖尿病患者全因死亡率、心血管死亡率、心肌梗死和卒中的影响:系统评价和荟萃分析
Steven P Marso,Kevin F Kennedy,John A House et al.
Steven P Marso et al.
We performed a meta-analysis of studies evaluating the effect of intensive glucose control on major adverse cardiovascular events in patients with type 2 diabetes from 1990 to 2009. A search of the published literature and the Cochran Centr...
Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus [0.03%]
高同型半胱氨酸症与血管功能紊乱及心血管疾病和死亡率的关系及其与糖尿病的相互作用关系研究进展
Maike Anderssohn,Edzard Schwedhelm,Nicole Lüneburg et al.
Maike Anderssohn et al.
Asymmetric dimethylarginine (ADMA) has evolved as an important regulator of nitric oxide (NO) synthesis in recent years. Elevated levels of ADMA have been reported in many conditions associated with a high cardiovascular risk. Moreover, ADM...