Increased prevalence of cardiovascular disease and risk biomarkers in patients with unknown type 2 diabetes visiting cardiology specialists: results from the DIASPORA study [0.03%]
DIASPORA研究：心血管病及其危险因素在未知型2糖尿病心脏病患者中的高发性
Thomas Schöndorf,Georg Lübben,Efstrathios Karagiannis et al.
Thomas Schöndorf et al.
Background: Patients with diabetes mellitus and IGT have a high risk for cardiovascular events. It is tempting to speculate that these patients are often first seen by cardiologists. ...
Multicenter Study
Diabetes & vascular disease research. 2010 Apr;7(2):145-50. DOI:10.1177/1479164109358241 2010
The synthetic GLP-I receptor agonist, exenatide, reduces intimal hyperplasia in insulin resistant rats [0.03%]
合成GLP-1受体激动剂 Exenatide 对糖尿病抵抗型大鼠的内膜增生有抑制作用
Subramanyam N Murthy,Rose-Claire St Hilaire,David B Casey et al.
Subramanyam N Murthy et al.
We studied the effect of a synthetic GLP-1 receptor agonist, exenatide, a drug approved for the treatment of type 2 diabetes, on the recovery from vascular injury in Zucker (non-diabetic) fatty rats. Exenatide 5.0 microg/kg per day or salin...
Acute glucose dysmetabolism in the early phase of ST-elevation myocardial infarction: the age response [0.03%]
急性ST段抬高性心肌梗死早期糖代谢异常的年龄反应特征
Chiara Lazzeri,Serafina Valente,Marco Chiostri et al.
Chiara Lazzeri et al.
In elderly patients with AMI, hyperglycaemia is associated with increased mortality. Recently it has been observed that insulin resistance, as assessed by the HOMA index, proved an independent predictor of in-hospital mortality. The interac...
The effect of intensive glucose control on all-cause and cardiovascular mortality, myocardial infarction and stroke in persons with type 2 diabetes mellitus: a systematic review and meta-analysis [0.03%]
强化血糖控制对2型糖尿病患者全因死亡率、心血管死亡率、心肌梗死和卒中的影响：系统评价和荟萃分析
Steven P Marso,Kevin F Kennedy,John A House et al.
Steven P Marso et al.
We performed a meta-analysis of studies evaluating the effect of intensive glucose control on major adverse cardiovascular events in patients with type 2 diabetes from 1990 to 2009. A search of the published literature and the Cochran Centr...
Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus [0.03%]
高同型半胱氨酸症与血管功能紊乱及心血管疾病和死亡率的关系及其与糖尿病的相互作用关系研究进展
Maike Anderssohn,Edzard Schwedhelm,Nicole Lüneburg et al.
Maike Anderssohn et al.
Asymmetric dimethylarginine (ADMA) has evolved as an important regulator of nitric oxide (NO) synthesis in recent years. Elevated levels of ADMA have been reported in many conditions associated with a high cardiovascular risk. Moreover, ADM...
The BARI 2D study: a randomised trial of therapies for type 2 diabetes and coronary artery disease [0.03%]
BARI 2D研究：2型糖尿病并冠状动脉疾病患者治疗方案的随机对照试验
Martin K Rutter,Richard W Nesto
Martin K Rutter
The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial randomized 2368 patients with type 2 diabetes (T2DM) and coronary artery disease to either prompt revascularization or intensive medical therapy alone; and to...
Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population [0.03%]
卡帕辛10基因的危险型和保护型基因在印度东部2型糖尿病患者中的共存现象
Sangeeta Adak,Sanghamitra Sengupta,Subhankar Chowdhury et al.
Sangeeta Adak et al.
Linkage and association studies have detected a role for Calpain-10 (CAPN10) polymorphisms in susceptibility to T2DM in many populations. This study aimed to evaluate possible associations between three SNPs in the CAPN10 (UCSNPs -43, -19 a...
The PPARgamma Pro12Ala variant is associated with insulin sensitivity in Russian normoglycaemic and type 2 diabetic subjects [0.03%]
PPARγ的Pro12Ala变异体与俄罗斯正常血糖和2型糖尿病受试者的胰岛素敏感性有关
Dimitry A Chistiakov,Viktor A Potapov,Dmitry S Khodirev et al.
Dimitry A Chistiakov et al.
The second isoform of the PPARgamma2 is specific for adipose tissue. In adipocytes, this isoform is involved in the regulation of adipogenesis and lipid storage, insulin and glucose metabolism. Pro12Ala, a missense mutation in exon 2 of PPA...
Lipoprotein-associated phospholipase A2, C-reactive protein, and coronary artery disease in individuals with type 1 diabetes and macroalbuminuria [0.03%]
与1型糖尿病和大量白蛋白尿相关的载脂蛋白相关磷脂酶A2、C反应蛋白及冠状动脉疾病
Rachel G Miller,Tina Costacou,Trevor J Orchard
Rachel G Miller
Given the paucity of data in type 1 diabetes concerning lipoprotein-associated phospholipase A( 2) (Lp-PLA(2)), we examined its prospective relationship with coronary artery disease (CAD), as well as the effect of modification by C-reactive...
Hairong Nan,Zengchang Pang,Shaojie Wang et al.
Hairong Nan et al.
The objective of this study was to investigate the association of serum UA with either FPG or 2hPG levels among Chinese adults in Qingdao, China. A population-based survey for diabetes was performed in 2006 in Qingdao. The survey included 1...