Antithrombotic therapy in patients with diabetes mellitus and coronary artery disease [0.03%]
糖尿病合并冠心病患者的抗栓治疗
José Luis Ferreiro,Ángel R Cequier,Dominick J Angiolillo
José Luis Ferreiro
Currently approved antiplatelet treatment strategies have proved successful for reducing cardiovascular adverse events in patients with CAD. However, despite the use of recommended antiplatelet treatment strategies, the presence of DM has b...
José Luis Ferreiro,Joan Antoni Gómez-Hospital,Dominick J Angiolillo
José Luis Ferreiro
Patients with diabetes mellitus (DM) have accelerated atherosclerosis, which is the main underlying factor contributing to the high risk of atherothrombotic events in these patients. Atherothrombotic complications are the leading cause of m...
Small-dense LDL and LDL glycation in metabolic syndrome and in statin-treated and non-statin-treated type 2 diabetes [0.03%]
代谢综合征和他汀治疗及非他汀治疗的2型糖尿病中的小而密LDL和LDL糖基化
Nahla N Younis,Handrean Soran,Reena Sharma et al.
Nahla N Younis et al.
Small-dense LDL (SD-LDL) has been particularly implicated in atherosclerosis. It has previously been reported that in non-diabetic people SD-LDL is preferentially glycated. The distribution of glycated apolipoprotein B (glyc-apoB) in lipopr...
S H Alzahrani,R A Ajjan
S H Alzahrani
Atherothrombotic complications are the main cause of mortality in subjects with diabetes. Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors with associated hypofibrinolysis all contribute to incr...
Effects of admission serum urea, glomerular filtration rate, proteinuria and diabetes status on 3-month mortality after acute stroke [0.03%]
入院时血清尿素、肾小球滤过率、蛋白尿和糖尿病状态对急性脑卒中后3个月死亡率的影响
Iskandar Idris,Robert Hill,Jagdish C Sharma
Iskandar Idris
Mark T Kearney
Mark T Kearney
Niacin improves small artery vasodilatory function and compliance in statin-treated type 2 diabetic patients [0.03%]
烟酸改善他汀治疗的2型糖尿病患者的中小动脉血管舒张功能和顺应性
Sandra J Hamilton,Gerard T Chew,Timothy M E Davis et al.
Sandra J Hamilton et al.
We investigated the effect of niacin (nicotinic acid prolonged release) on forearm vasodilatory function and arterial compliance in statin-treated type 2 diabetic patients with endothelial dysfunction. In a parallel group study, we randomis...
Randomized Controlled Trial
Diabetes & vascular disease research. 2010 Oct;7(4):296-9. DOI:10.1177/1479164110376206 2010
Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics [0.03%]
两周牛磺酸补充逆转年轻1型糖尿病男性的内皮功能障碍
Michael A Moloney,Rowan G Casey,David H O&#x;Donnell et al.
Michael A Moloney et al.
Type 1 diabetics have a well-recognised risk of accelerated cardiovascular disease. Even in the absence of clinical signs there are detectable abnormalities of conduit vessel function. Our group has previously reported reversal of endotheli...
Randomized Controlled Trial
Diabetes & vascular disease research. 2010 Oct;7(4):300-10. DOI:10.1177/1479164110375971 2010
Reduced negative surface charge on arterial endothelium explains accelerated atherosclerosis in type 2 diabetic patients [0.03%]
2型糖尿病患者的动脉内皮负电荷降低可解释动脉粥样硬化的加速形成
Mohammad Nassimizadeh,Houman Ashrafian,Nigel E Drury et al.
Mohammad Nassimizadeh et al.
Reduced endothelial surface charge markedly increases the rate of LDL uptake into blood vessels. Previous work in the streptozotocin diabetic rat reported reduced endothelial surface charge. We compared endothelial surface charge density in...
Non-LDL-related dyslipidaemia and coronary risk: a case-control study [0.03%]
非LDL相关性血脂异常与冠心病关系的病例对照研究
Gerd Assmann,Paul Cullen,Helmut Schulte
Gerd Assmann
To assess the non-LDL-C-related dyslipidaemia risk of MI, 823 men aged 23 to 65 with a first MI were compared with 823 MI-free PROCAM controls matched for sex, age, smoking, DM, BP and LDL-C. Overall, the odds of MI in men with HDL-C < 1.15...