Safety and efficacy of saxagliptin added to thiazolidinedione over 76 weeks in patients with type 2 diabetes mellitus [0.03%]
西格列汀联合噻唑烷二酮类药物治疗2型糖尿病患者的有效性和安全性(长达76周)
Priscilla L Hollander,Jia Li,Robert Frederich et al.
Priscilla L Hollander et al.
To assess the long-term efficacy and safety of saxagliptin in patients with type 2 diabetes mellitus inadequately controlled with thiazolidinedione monotherapy, 565 patients were randomised to saxagliptin (2.5 mg or 5 mg) or placebo added t...
A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model [0.03%]
利拉鲁肽通过GLP-1受体抑制动脉粥样硬化血管炎症反应小鼠模型的内皮细胞功能紊乱及粘附分子表达
Tracey Gaspari,HongBin Liu,Iresha Welungoda et al.
Tracey Gaspari et al.
The glucagon like peptide-1 receptor (GLP-1R) agonist liraglutide attenuates induction of plasminogen activator inhibitor type-1 (PAI-1) and vascular adhesion molecule (VAM) expression in human vascular endothelial cells (hVECs) in vitro an...
Relationships among insulin resistance, obesity, diagnosis of the metabolic syndrome and cardio-metabolic risk [0.03%]
胰岛素抵抗、肥胖、代谢综合征的诊断及心血管和代谢风险之间的关系
Martin R Salazar,Horacio A Carbajal,Walter G Espeche et al.
Martin R Salazar et al.
The aim of this study is to test the hypotheses that: 1) diagnosing the metabolic syndrome does not effectively identify insulin-resistant (IR) individuals; and 2) waist circumference (WC) is no better than body mass index (BMI) in predicti...
Assessment of cardiac structure and function in patients without and with peripheral oedema during rosiglitazone treatment [0.03%]
罗格列酮治疗期间无下肢水肿和有下肢水肿患者的评价心脏结构与功能的研究
Nikhil Narang,Sumiko I Armstead,Amanda Stream et al.
Nikhil Narang et al.
Background: Thiazolidinediones cause peripheral oedema, the aetiology of which remains poorly understood. Methods: In a sub-study of a ...
Randomized Controlled Trial
Diabetes & vascular disease research. 2011 Apr;8(2):101-8. DOI:10.1177/1479164111403334 2011
Adiponectin and cardiovascular risk profile in patients with type 2 diabetes mellitus: parameters associated with adiponectin complex distribution [0.03%]
2型糖尿病患者脂联素与心血管危险因素分布的关系研究
Mark P Hamilton,M Odette Gore,Colby R Ayers et al.
Mark P Hamilton et al.
Aims: Plasma levels of the adipokine adiponectin are accepted as excellent correlates to metabolic health. Here, we aim to characterise associations between circulating plasma adiponectin complexes and baseline parameters...
Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrome and hypothyroidism [0.03%]
二甲双胍可降低体重超标并且卵巢多囊和甲状腺功能减退妇女的促甲状腺素水平
S Morteza Taghavi,Hale Rokni,Sedigheh Fatemi
S Morteza Taghavi
Objective: To assess the effect of metformin administration on thyroid function in overweight women with polycystic ovarian syndrome (PCOS). Methods: ...
Insulin resistance and cardiovascular disease risk factors in subjects with prehypertension [0.03%]
高血压前期患者的胰岛素抵抗与心血管疾病危险因素的关系
Hilla Knobler,Fahim Abbasi,Cindy Lamendola et al.
Hilla Knobler et al.
Prehypertension is considered to be associated with increased cardiovascular disease (CVD), and some data suggest that insulin resistance is common in this group. The goal of this study was to quantify insulin action by determining the stea...
Correlates of acute insulin resistance in the early phase of non-diabetic ST-elevation myocardial infarction [0.03%]
非糖尿病ST段抬高型心肌梗死早期急性胰岛素抵抗的影响因素
Chiara Lazzeri,Serafina Valente,Marco Chiostri et al.
Chiara Lazzeri et al.
The relationship between insulin secretion and acute insulin resistance (as assessed by Homeostatic Model Assessment [HOMA] index) and clinical and biochemical parameters in the early phase of non-diabetic ST-elevation myocardial infarction...
Validation of the Chinese version of the Walking Impairment Questionnaire in patients with both peripheral arterial disease and type 2 diabetes mellitus [0.03%]
外周动脉疾病合并2型糖尿病患者中用于评估步行障碍问卷中文版可靠性和有效性的研究
Jie Wang,Yan Cui,Rong-Wen Bian et al.
Jie Wang et al.
The aim of present study is to translate and validate a Chinese version of the WIQ in patients with PAD and T2DM. A cross-sectional survey was conducted. After translation, a convenience sample of 59 patients with PAD and T2DM completed the...
Oxidative stress, antioxidant status and lipid profile in the saliva of type 2 diabetics [0.03%]
2型糖尿病患者唾液氧化应激、抗氧化能力及血脂情况
Natheer H Al-Rawi
Natheer H Al-Rawi
Background: The aim of this study was to assess the salivary content of lipid peroxidation and antioxidants in patients with type 2 diabetes. Method: ...