Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes [0.03%]
伴或不伴有糖尿病的患者使用依折麦布/他汀类药物联合治疗实现推荐脂质和脂蛋白水平的效果优于单独使用他汀类药物
John R Guyton,D John Betteridge,Michel Farnier et al.
John R Guyton et al.
Treatment guidelines identify low-density lipoprotein cholesterol (LDL-C) as the primary target of therapy with secondary targets of non-high-density lipoprotein cholesterol (non-HDL-C) and apolipoprotein B (apoB). Data were pooled from 27 ...
Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks [0.03%]
沙格列汀配合减量磺脲类药物与增量磺脲类药物联合用药的76周安全性及有效性比较研究
Antonio R Chacra,Gerry H Tan,Shoba Ravichandran et al.
Antonio R Chacra et al.
To assess the long-term efficacy and safety of saxagliptin in patients with type 2 diabetes mellitus inadequately controlled on sulphonylurea monotherapy, 768 patients were randomised to saxagliptin 2.5 or 5 mg in combination with glyburide...
Randomized Controlled Trial
Diabetes & vascular disease research. 2011 Apr;8(2):150-9. DOI:10.1177/1479164111404574 2011
The predictive value of inflammatory activity and markers of the adipo-insular axis on restenosis in patients with type 2 diabetes [0.03%]
炎症活动和脂岛轴标志物对2型糖尿病患者血管重建后再狭窄预测价值的研究
Camilla Hage,Lars Grip,Klas Malmberg et al.
Camilla Hage et al.
Aims: Patients with type 2 diabetes (T2DM) have a high restenosis rate after percutaneous coronary intervention (PCI). This study investigated whether markers of inflammation and the adipo-insular axis associated with T2D...
Randomized Controlled Trial
Diabetes & vascular disease research. 2011 Apr;8(2):143-9. DOI:10.1177/1479164111403784 2011
Impaired compensatory response to hypovolaemic circulatory stress in type 1 diabetes mellitus [0.03%]
1型糖尿病患者对失血性循环应激的代偿反应受损
Marcus Lindenberger,Henrik Olsen,Toste Lanne
Marcus Lindenberger
Diabetes mellitus is associated with decreased haemodynamic stability and reduced tolerance to hypovolaemia. Compensatory haemodynamic responses during experimental hypovolaemia in type 1 diabetes patients with (DMR+) and without (DMR-) ret...
Safety and efficacy of saxagliptin added to thiazolidinedione over 76 weeks in patients with type 2 diabetes mellitus [0.03%]
西格列汀联合噻唑烷二酮类药物治疗2型糖尿病患者的有效性和安全性（长达76周）
Priscilla L Hollander,Jia Li,Robert Frederich et al.
Priscilla L Hollander et al.
To assess the long-term efficacy and safety of saxagliptin in patients with type 2 diabetes mellitus inadequately controlled with thiazolidinedione monotherapy, 565 patients were randomised to saxagliptin (2.5 mg or 5 mg) or placebo added t...
A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model [0.03%]
利拉鲁肽通过GLP-1受体抑制动脉粥样硬化血管炎症反应小鼠模型的内皮细胞功能紊乱及粘附分子表达
Tracey Gaspari,HongBin Liu,Iresha Welungoda et al.
Tracey Gaspari et al.
The glucagon like peptide-1 receptor (GLP-1R) agonist liraglutide attenuates induction of plasminogen activator inhibitor type-1 (PAI-1) and vascular adhesion molecule (VAM) expression in human vascular endothelial cells (hVECs) in vitro an...
Relationships among insulin resistance, obesity, diagnosis of the metabolic syndrome and cardio-metabolic risk [0.03%]
胰岛素抵抗、肥胖、代谢综合征的诊断及心血管和代谢风险之间的关系
Martin R Salazar,Horacio A Carbajal,Walter G Espeche et al.
Martin R Salazar et al.
The aim of this study is to test the hypotheses that: 1) diagnosing the metabolic syndrome does not effectively identify insulin-resistant (IR) individuals; and 2) waist circumference (WC) is no better than body mass index (BMI) in predicti...
Assessment of cardiac structure and function in patients without and with peripheral oedema during rosiglitazone treatment [0.03%]
罗格列酮治疗期间无下肢水肿和有下肢水肿患者的评价心脏结构与功能的研究
Nikhil Narang,Sumiko I Armstead,Amanda Stream et al.
Nikhil Narang et al.
Background: Thiazolidinediones cause peripheral oedema, the aetiology of which remains poorly understood. Methods: In a sub-study of a ...
Randomized Controlled Trial
Diabetes & vascular disease research. 2011 Apr;8(2):101-8. DOI:10.1177/1479164111403334 2011
Adiponectin and cardiovascular risk profile in patients with type 2 diabetes mellitus: parameters associated with adiponectin complex distribution [0.03%]
2型糖尿病患者脂联素与心血管危险因素分布的关系研究
Mark P Hamilton,M Odette Gore,Colby R Ayers et al.
Mark P Hamilton et al.
Aims: Plasma levels of the adipokine adiponectin are accepted as excellent correlates to metabolic health. Here, we aim to characterise associations between circulating plasma adiponectin complexes and baseline parameters...