Laura Venskutonyte,Lars Rydén,Göran Nilsson et al.
Laura Venskutonyte et al.
Objective: Hyperglycaemia enhances the risk of cardiovascular events and death, while high-density lipoprotein cholesterol (HDLc) is protective. Information on these associations among the elderly population is scanty. We...
Gopalakrishnan Ramakrishnan,Albina Arjuman,Shilpa Suneja et al.
Gopalakrishnan Ramakrishnan et al.
The insulin receptor (IR) and low-density lipoprotein receptor (LDLR) maintain glucose and lipid metabolism, respectively. Diabetes is associated with increased blood glucose, dyslipidaemia and increased risk of atherosclerosis. We hypothes...
Complement C3 is a novel plasma clot component with anti-fibrinolytic properties [0.03%]
补体C3是一种具有抗纤溶作用的新型血浆凝块成分
Joanna-Marie Howes,Victoria R Richardson,Kerrie A Smith et al.
Joanna-Marie Howes et al.
Background and method: Increased plasma clot density and prolonged lysis times are associated with cardiovascular disease. In this study, we employed a functional proteomics approach to identify novel clot components whic...
Waist circumference is a strong and independent determinant of the distribution of HDL subfractions in overweight patients with cardiovascular risk factors [0.03%]
腰围是心血管危险因素肥胖患者的HDL亚组分分布的强而独立的决定因素
David Rosenbaum,Boris Hansel,Dominique Bonnefont-Rousselot et al.
David Rosenbaum et al.
Purpose: Our aim was to determine the influence of waist circumference on the repartition of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) subfractions in patients with increased waist perimeter and one...
Sub-optimal achievement of guideline-derived lipid goals in management of diabetes patients with atherosclerotic cardiovascular disease, despite high use of evidence-based therapies [0.03%]
血脂达标率偏低仍可导致糖尿病合并动脉粥样硬化性心血管疾病患者预后恶化，基于证据的治疗或可改变该趋势
Pamela B DeGuzman,Kwame O Akosah,Allan G Simpson et al.
Pamela B DeGuzman et al.
Guidelines recommend aggressive goals for lipid and blood pressure reduction for high risk patients with diabetes mellitus and atherosclerotic coronary disease. However, it remains unclear how many patients achieve treatment goals versus th...
Thor Ueland,Pål Aukrust,Svend Aakhus et al.
Thor Ueland et al.
Background: Silent coronary artery disease is a frequent complication of type 2 diabetes (T2DM). Based on its multiple roles in inflammation, atherogenesis and glucose homeostasis, we hypothesised that activin A could be ...
Comparative efficacy and safety of fenofibrate/pravastatin plus ezetimibe triple therapy and simvastatin/ezetimibe dual therapy in type 2 diabetic patients with mixed hyperlipidaemia and cardiovascular disease [0.03%]
评估非诺贝特/普伐他汀联合依折麦布与辛伐他汀/依折麦布在2型糖尿病混合高脂血症心血管病患者中的疗效及安全性：一项真实世界研究
Michel Farnier,Kjetil Retterstøl,Armin Steinmetz et al.
Michel Farnier et al.
Background: This study was designed to compare the efficacy and safety of a fenofibrate/pravastatin 160/40 mg fixed-dose combination plus ezetimibe 10 mg triple therapy and simvastatin 20 mg plus ezetimibe 10 mg dual ther...
Randomized Controlled Trial
Diabetes & vascular disease research. 2012 Jul;9(3):205-15. DOI:10.1177/1479164111430715 2012
Gender-based divergence of cardiovascular outcomes in asymptomatic patients with type 2 diabetes: results from the DIAD study [0.03%]
基于性别的无症状2型糖尿病患者心血管结局差异：DIAD研究结果分析
Suman Tandon,Frans J T Wackers,Silvio E Inzucchi et al.
Suman Tandon et al.
Gender differences in cardiovascular outcomes were compared in asymptomatic men and women with type 2 diabetes (T2DM) in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study. Of 1123 participants, 290 men and 271 women were rand...
Randomized Controlled Trial
Diabetes & vascular disease research. 2012 Apr;9(2):124-30. DOI:10.1177/1479164111431470 2012
Impact of metabolic syndrome on re-stenosis development: role of drug-eluting stents [0.03%]
代谢综合征对再狭窄发生的影响：药物洗脱支架的作用
S N Goyal,S Bharti,B Krishnamurthy et al.
S N Goyal et al.
Metabolic syndrome (MetS) is defined as a cluster of numerous cardiovascular risk factors, which encompasses obesity, dyslipidaemia, insulin resistance and hypertension. Patients with MetS are more prone to developing cardiovascular events ...
Impaired alternative macrophage differentiation of peripheral blood mononuclear cells from obese subjects [0.03%]
肥胖患者外周血单个核细胞的替代巨噬细胞分化受损
Gael Bories,Robert Caiazzo,Bruno Derudas et al.
Gael Bories et al.
Visceral obesity is a chronic, low-grade inflammatory disease that predisposes people to the metabolic syndrome, type 2 diabetes and its cardiovascular complications. Adipose tissue is not a passive storehouse for fat, but an endocrine orga...