Ablation of angiotensin type 2 receptor prevents endothelial nitric oxide synthase glutathionylation and nitration in ischaemic abductor muscle of diabetic mice [0.03%]
糖尿病小鼠缺血外展肌中血管紧张素Ⅱ受体的消融可防止内皮型一氧化氮合酶的谷胱甘肽化和硝化作用
Stéphanie Robillard,Clément Mercier,Valérie Breton et al.
Stéphanie Robillard et al.
Peripheral artery disease is a severe complication of diabetes. We have reported that the deletion of angiotensin type 2 receptor in diabetic mice promoted vascular angiogenesis in the ischaemic muscle 4 weeks following ischaemia. However, ...
Seasonal variation in home blood pressure and its relationship with room temperature in patients with type 2 diabetes [0.03%]
2型糖尿病患者的家庭血压季节性变化及其与室内温度的关系
Emi Ushigome,Nobuko Kitagawa,Aya Kitae et al.
Emi Ushigome et al.
Our aim was to examine the seasonal variations in home blood pressure measurements and the relationship of ambient temperature or room temperature with the seasonal variations in home blood pressure measurements using a home blood pressure ...
Effect of empagliflozin on brachial artery shear stress and endothelial function in subjects with type 2 diabetes: Results from an exploratory study [0.03%]
恩格列净对2型糖尿病患者上臂动脉剪切应力及内皮功能的影响:一项探索性研究的结果
Concetta Irace,Antonio Cutruzzolà,Martina Parise et al.
Concetta Irace et al.
Empagliflozin reduces the risk of cardiovascular mortality in subjects with type 2 diabetes. We demonstrated that empagliflozin increases blood viscosity and carotid shear stress and decreases carotid wall thickness. Shear stress is the for...
Improvements in diabetic albuminuria and podocyte differentiation following Roux-en-Y gastric bypass surgery [0.03%]
胃旁路手术对糖尿病性血尿和足细胞分化的影响
Aoife L Canney,Ricardo V Cohen,Jessie A Elliott et al.
Aoife L Canney et al.
Background: Multiple studies demonstrate an albuminuria-lowering impact of Roux-en-Y gastric bypass surgery, but neither evaluation of its penetrance across different baseline levels of albuminuria nor its association wit...
Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis [0.03%]
糖尿病引起的动脉粥样硬化小鼠模型主动脉心瓣早期分子和功能变化
Monica Madalina Tucureanu,Alexandru Filippi,Nicoleta Alexandru et al.
Monica Madalina Tucureanu et al.
Diabetes contributes directly to the development of cardiovascular aortic valve disease. There is currently no drug therapy available for a dysfunctional valve and this urges the need for additional research to identify distinctive mechanis...
Elevated admission glucose is common and associated with high short-term complication burden after acute myocardial infarction: Insights from the VALIDATE-SWEDEHEART study [0.03%]
急性心肌梗死后升高的入院血糖很常见,并且与短期并发症负担重相关:来自VALIDATE-SWEDEHEART研究的启示
Viveca Ritsinger,Jens Jensen,Daniel Ohm et al.
Viveca Ritsinger et al.
Objective: To investigate the association between admission plasma glucose and cardiovascular events in patients with acute myocardial infarction treated with modern therapies including early percutaneous coronary interve...
Randomized Controlled Trial
Diabetes & vascular disease research. 2019 Nov;16(6):582-584. DOI:10.1177/1479164119871540 2019
Fructose causes endothelial cell damage via activation of advanced glycation end products-receptor system [0.03%]
果糖通过激活晚期糖基化终产物受体系统造成内皮细胞损伤
Ami Sotokawauchi,Takanori Matsui,Yuichiro Higashimoto et al.
Ami Sotokawauchi et al.
Objective: Advanced glycation end products and their receptor - RAGE - in the adipose tissues contribute to metabolic derangements in fructose-fed rats. However, it remains unclear whether fructose could cause endothelial...
Impact of diabetes on outcomes of cardiac surgery in a multiethnic Southeast Asian population [0.03%]
糖尿病对多民族东南亚人群心脏手术结果的影响
Vikaesh Moorthy,Weiling Liu,Sophia Tsong Huey Chew et al.
Vikaesh Moorthy et al.
Although diabetes is rapidly increasing in Asia and has been shown to be associated with worse cardiac surgery outcomes, no research has been done to study the impact of diabetes on cardiac surgery outcomes in a Southeast Asian cohort. Henc...
Hypermetabolism and impaired endothelium-dependent vasodilation in mesenteric arteries of type 2 diabetes mellitus db/db mice [0.03%]
2型糖尿病(db/db小鼠)肠系膜动脉的高代谢和内皮依赖性血管扩张障碍
Lene Arildsen,Jens Velde Andersen,Helle Soenderby Waagepetersen et al.
Lene Arildsen et al.
Besides being a metabolic disease, diabetes is considered a vascular disease as many of the complications relate to vascular pathologies. The aim of this study was to investigate how vascular tone and reactivity and vascular cell metabolism...
Association of serum FAM19A5 with metabolic and vascular risk factors in human subjects with or without type 2 diabetes [0.03%]
FAM19A5与人类2型糖尿病患者和非患者的代谢及血管危险因素的相关性研究
You-Bin Lee,Hwan-Jin Hwang,Jung A Kim et al.
You-Bin Lee et al.
Objectives: A recent experimental study revealed that family with sequence similarity 19 [chemokine (C-C motif)-like] member A5 (FAM19A5), a novel secreted adipokine, has inhibitory effects on vascular smooth muscle cell ...
Comparative Study
Diabetes & vascular disease research. 2019 Nov;16(6):530-538. DOI:10.1177/1479164119860746 2019