Genetic variation in CARD8, a gene coding for an NLRP3 inflammasome-associated protein, alters the genetic risk for diabetic nephropathy in the context of type 2 diabetes mellitus [0.03%]
糖尿病肾病的遗传风险改变背景下编码NLRP3炎性小体相关蛋白CARD8基因的遗传变异导致了2型糖尿病患者中糖尿病肾病的遗传风险改变
Fotis Tsetsos,Athanasios Roumeliotis,Xanthippi Tsekmekidou et al.
Fotis Tsetsos et al.
Background: Approximately one third of type 2 diabetes mellitus (T2DM) cases present with diabetic nephropathy (DN), the leading cause of end-stage renal disease. Inflammation plays an important role in T2DM disease and D...
Prevalence and predictors of peripheral arterial disease determined by ankle brachial index in diabetes population treated within primary care services in a non-urban area of lower northern Thailand [0.03%]
泰国东北非城市地区初级保健中糖尿病患者外周动脉疾病的患病率和踝臂指数的预测因素
Preaw Suwannasrisuk,Sarinya Sattanon,Watcharaporn Taburee et al.
Preaw Suwannasrisuk et al.
In diabetes patients, urban lifestyle has been concerned as one of the risk factors for peripheral arterial disease (PAD). The aims of this study were to find out the prevalence and associated risk factors of PAD in type 2 diabetes patients...
Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction [0.03%]
LIBERATES试验的原理和设计：对于最近心肌梗死的二型糖尿病患者使用瞬时血糖监测以达到优化血糖控制效果的随机对照试验方案
Colin C Everett,Catherine Reynolds,Catherine Fernandez et al.
Colin C Everett et al.
Hyperglycaemia in individuals with type 2 diabetes (T2D) and myocardial infarction (MI) is associated with guarded clinical prognosis. Studies improving glucose levels in T2D following MI relied on HbA1c as the main glycaemic marker, failin...
Naoya Osaka,Hideki Kushima,Yusaku Mori et al.
Naoya Osaka et al.
Although glucagon has been shown to exert pleiotropic actions in various types of cells and organs through the interaction with its receptor, its pathophysiological role in atherosclerotic cardiovascular disease remains unclear. Here, we ex...
High hemoglobin glycation index is associated with increased systemic arterial stiffness independent of hyperglycemia in real-world Japanese population: A cross-sectional study [0.03%]
高血红蛋白糖基化指数与日本普通人群中独立于高血糖的增加的系统动脉僵硬度有关：一项横断面研究
Daiji Nagayama,Yasuhiro Watanabe,Takashi Yamaguchi et al.
Daiji Nagayama et al.
Aims: To investigate the association of metabolic parameters including hemoglobin glycation index (HGI, observed HbA1c - predicted HbA1c) with systemic arterial stiffness assessed by cardio-ankle vascular index (CAVI). ...
Coronary flow impairment in asymptomatic patients with early stage type-2 diabetes: Detection by FFRCT [0.03%]
早期二型糖尿病无症状患者冠状动脉血流受损情况：通过FFRCT检测
Monija Mrgan,Bjarne Linde Nørgaard,Damini Dey et al.
Monija Mrgan et al.
Purpose: To determine the occurrence of physiological significant coronary artery disease (CAD) by coronary CT angiography (CTA) derived fractional flow reserve (FFRCT) in asymptomatic patients with a new diagnosis (0.75 ...
Evaluation of the relationship between cardiac autonomic function and glucose variability and HOMA-IR in prediabetes [0.03%]
心脏自主神经功能与葡萄糖变异度和HOMA-IR在糖尿病前期的关系的评估
Rumyana Dimova,Nevena Chakarova,Greta Grozeva et al.
Rumyana Dimova et al.
Aims: The present study aims to investigate the relationship between cardiac autonomic function (CAF) and glucose variability (GV) and HOMA-IR in subjects with prediabetes and normal glucose tolerance (NGT). ...
An optical coherence tomography comparison of coronary arterial plaque calcification in patients with end-stage renal disease and diabetes mellitus [0.03%]
糖尿病终末期肾病患者的冠状动脉斑块钙化的光学相干断层扫描比较研究
Joseph R Weber,Brendan Martin,Nicholas Kassis et al.
Joseph R Weber et al.
Background: Coronary arterial plaques in patients with end-stage renal disease (ESRD) are assumed to have increased calcification due to underlying renal disease or initiation of dialysis. This relationship may be confoun...
Risk of orthostatic hypotension associated with sodium-glucose cotransporter-2 inhibitor treatment: A meta-analysis of randomized controlled trials [0.03%]
钠-葡萄糖协同转运蛋白-2抑制剂治疗与体位性低血压风险的相关性：一项随机对照试验的荟萃分析
Xi Rong,Xinran Li,Qiling Gou et al.
Xi Rong et al.
Objective: The aim of this study was to assess the association between sodium-glucose cotransporter-2 (SGLT2) inhibitors and the risk of orthostatic hypotension (OH) in patients with type 2 diabetes mellitus (T2DM). ...
Timed physical exercise does not influence circadian rhythms and glucose tolerance in rotating night shift workers: The EuRhythDia study [0.03%]
定时锻炼对轮班工作者的昼夜节律和葡萄糖耐受量无影响：EuRhythDia研究
Juliane Hannemann,Anika Laing,Karin Glismann et al.
Juliane Hannemann et al.
Objectives: Night shift workers are at cardiometabolic risk due to circadian misalignment. We investigated whether infrequent exercise before each night shift that intentionally would not improve physical performance impr...
Randomized Controlled Trial
Diabetes & vascular disease research. 2020 May-Jun;17(5):1479164120950616. DOI:10.1177/1479164120950616 2020