Testing for population differences in evolutionary responses to pesticide pollution in brown trout (Salmo trutta) [0.03%]
测试褐 Trout(Salmo trutta)对农药污染的进化反应的种群差异的方法
David Nusbaumer,Lucas Marques da Cunha,Claus Wedekind
David Nusbaumer
Pesticides are often toxic to nontarget organisms, especially to those living in rivers that drain agricultural land. The brown trout (Salmo trutta) is a keystone species in many such rivers, and natural populations have hence been chronica...
Comparison of anadromous and landlocked Atlantic salmon genomes reveals signatures of parallel and relaxed selection across the Northern Hemisphere [0.03%]
裂腹大西洋鲑和陆锁大西洋鲑基因组的比较揭示了北美地区的平行选择与放松选择信号
Erik Kjærner-Semb,Rolf B Edvardsen,Fernando Ayllon et al.
Erik Kjærner-Semb et al.
Most Atlantic salmon (Salmo salar L.) populations follow an anadromous life cycle, spending early life in freshwater, migrating to the sea for feeding, and returning to rivers to spawn. At the end of the last ice age ~10,000 years ago, seve...
Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus) [0.03%]
疥螨严重程度与黄石国家公园狼(Canis lupus)基因组多态性降低及选择信号的相关性研究
Alexandra L DeCandia,Edward C Schrom,Ellen E Brandell et al.
Alexandra L DeCandia et al.
Population genetic theory posits that molecular variation buffers against disease risk. Although this "monoculture effect" is well supported in agricultural settings, its applicability to wildlife populations remains in question. In the pre...
On the estimation of inbreeding depression using different measures of inbreeding from molecular markers [0.03%]
基于分子标记的不同近交度估计方法评估纯合子衰退效应
Armando Caballero,Beatriz Villanueva,Tom Druet
Armando Caballero
The inbreeding coefficient (F) of individuals can be estimated from molecular marker data, such as SNPs, using measures of homozygosity of individual markers or runs of homozygosity (ROH) across the genome. These different measures of F can...
Within-patient phylogenetic reconstruction reveals early events in Barrett's Esophagus [0.03%]
患者内系谱重建揭示食管巴雷特综合征早期事件
Lucian P Smith,Jon A Yamato,Patricia C Galipeau et al.
Lucian P Smith et al.
Barrett's Esophagus is a neoplastic condition which progresses to esophageal adenocarcinoma in 5% of cases. Key events affecting the outcome likely occur before diagnosis of Barrett's and cannot be directly observed; we use phylogenetic ana...
Whole-genome SNP markers reveal conservation status, signatures of selection, and introgression in Chinese Laiwu pigs [0.03%]
全基因组SNP标记揭示了中国莱芜猪的保护状况、选择信号和杂交痕迹
Xiaopeng Wang,Hui Zhang,Min Huang et al.
Xiaopeng Wang et al.
Laiwu pigs are a Chinese indigenous breed that is renowned for its exceptionally high intramuscular fat content (average greater than 6%), providing an excellent genetic resource for the genetic improvement of meat quality of modern commerc...
Comparative transcriptomics of ice-crawlers demonstrates cold specialization constrains niche evolution in a relict lineage [0.03%]
冰crawler的比较转录组学表明冷适应限制了孑遗类群的生态位演化
Sean D Schoville,Sabrina Simon,Ming Bai et al.
Sean D Schoville et al.
Key changes in ecological niche space are often critical to understanding how lineages diversify during adaptive radiations. However, the converse, or understanding why some lineages are depauperate and relictual, is more challenging, as ma...
Suppressing evolution in genetically engineered systems through repeated supplementation [0.03%]
通过重复补充抑制遗传工程系统中的进化变迁
Nathan C Layman,Beth M Tuschhoff,Andrew J Basinski et al.
Nathan C Layman et al.
Genetically engineered organisms are prone to evolve in response to the engineering. This evolution is often undesirable and can negatively affect the purpose of the engineering. Methods that maintain the stability of engineered genomes are...
Maintenance of variation in virulence and reproduction in populations of an agricultural plant pathogen [0.03%]
农业植物病原体种群中毒力和繁殖变异性的维持
Anik Dutta,Daniel Croll,Bruce A McDonald et al.
Anik Dutta et al.
Genetic diversity within pathogen populations is critically important for predicting pathogen evolution, disease outcomes and prevalence. However, we lack a good understanding of the processes maintaining genetic variation and constraints o...
Niche-neutral theoretic approach to mechanisms underlying the biodiversity and biogeography of human microbiomes [0.03%]
中性理论在人类微生物群落多样性及分布研究中的应用综述
Zhanshan Sam Ma
Zhanshan Sam Ma
The human microbiome consists of five major regional biomes distributed in or on our five body sites including skin, oral, lung, gut, and reproductive tract. Its biogeography (the spatial and temporal distribution of its biodiversity) has f...