Large-scale prediction of protein ubiquitination sites using a multimodal deep architecture [0.03%]
基于多模深度架构的蛋白质泛素化位点的大规模预测
Fei He,Rui Wang,Jiagen Li et al.
Fei He et al.
Background: Ubiquitination, which is also called "lysine ubiquitination", occurs when an ubiquitin is attached to lysine (K) residues in targeting proteins. As one of the most important post translational modifications (P...
Modeling antibiotic resistance in the microbiota using multi-level Petri Nets [0.03%]
使用多级Petri网模型微生物群落中的抗生素抗性
Roberta Bardini,Stefano Di Carlo,Gianfranco Politano et al.
Roberta Bardini et al.
Background: The unregulated use of antibiotics not only in clinical practice but also in farm animals breeding is causing a unprecedented growth of antibiotic resistant bacterial strains. This problem can be analyzed at d...
A multi-context learning approach for EEG epileptic seizure detection [0.03%]
一种基于多上下文学习的EEG癫痫发作检测方法
Ye Yuan,Guangxu Xun,Kebin Jia et al.
Ye Yuan et al.
Background: Epilepsy is a neurological disease characterized by unprovoked seizures in the brain. The recent advances in sensor technologies allow researchers to analyze the collected biological records to improve the tre...
An interpretable boosting model to predict side effects of analgesics for osteoarthritis [0.03%]
一种可解释的增强模型以预测骨关节炎止痛药副作用
Liangliang Liu,Ying Yu,Zhihui Fei et al.
Liangliang Liu et al.
Background: Osteoarthritis (OA) is the most common disease of arthritis. Analgesics are widely used in the treat of arthritis, which may increase the risk of cardiovascular diseases by 20% to 50% overall.There are few stu...
Recognition of bacteria named entity using conditional random fields in Spark [0.03%]
基于Spark的条件随机场的细菌命名实体识别
Xiaoyan Wang,Yichuan Li,Tingting He et al.
Xiaoyan Wang et al.
Background: Microbe plays a crucial role in the functional mechanism of an ecosystem. Identification of the interactions among microbes is an important step towards understand the structure and function of microbial commu...
On the reconstruction of the ancestral bacterial genomes in genus Mycobacterium and Brucella [0.03%]
关于重建结核分支细菌属和布鲁氏菌属祖先基因组的研究
Christophe Guyeux,Bashar Al-Nuaimi,Bassam AlKindy et al.
Christophe Guyeux et al.
Background: To reconstruct the evolution history of DNA sequences, novel models of increasing complexity regarding the number of free parameters taken into account in the sequence evolution, as well as faster and more acc...
Large scale study of anti-sense regulation by differential network analysis [0.03%]
基于差异网络分析的大规模反义调控研究
Marc Legeay,Sébastien Aubourg,Jean-Pierre Renou et al.
Marc Legeay et al.
Background: Systems biology aims to analyse regulation mechanisms into the cell. By mapping interactions observed in different situations, differential network analysis has shown its power to reveal specific cellular resp...
BioGraph: a web application and a graph database for querying and analyzing bioinformatics resources [0.03%]
BioGraph：一个用于查询和分析生物信息资源的网络应用和图数据库
Antonio Messina,Antonino Fiannaca,Laura La Paglia et al.
Antonio Messina et al.
Background: Several online databases provide a large amount of biomedical data of different biological entities. These resources are typically stored in systems implementing their own data model, user interface and query ...
Ultraviolet (IUV) and mass spectrometry (IMS) imaging for the deconvolution of microbial interactions [0.03%]
用于解析微生物互作的紫外(IUV)和质谱(IMS)成像技术
Víctor González-Menéndez,Germán Martínez,Rachel Serrano et al.
Víctor González-Menéndez et al.
Background: Spatial localization of natural products or proteins during microbial interactions can help to identify new antimicrobials both as offensive or defensive agents. Visible spatial interactions have been used for...
Improving the EFMs quality by augmenting their representativeness in LP methods [0.03%]
通过在LP方法中增强EFM的代表性来改善EFM的质量
José F Hidalgo,Jose A Egea,Francisco Guil et al.
José F Hidalgo et al.
Background: Although cellular metabolism has been widely studied, its fully comprehension is still a challenge. A main tool for this study is the analysis of meaningful pieces of knowledge called modes and, in particular,...