Prediction of protein self-interactions using stacked long short-term memory from protein sequences information [0.03%]
基于蛋白质序列信息的栈式长短时记忆预测蛋白质自相互作用
Yan-Bin Wang,Zhu-Hong You,Xiao Li et al.
Yan-Bin Wang et al.
Background: Self-interacting Proteins (SIPs) plays a critical role in a series of life function in most living cells. Researches on SIPs are important part of molecular biology. Although numerous SIPs data be provided, tr...
Integrating proteomic and phosphoproteomic data for pathway analysis in breast cancer [0.03%]
整合蛋白质组和磷酸化蛋白质组数据用于乳腺癌通路分析
Jie Ren,Bo Wang,Jing Li
Jie Ren
Background: As protein is the basic unit of cell function and biological pathway, shotgun proteomics, the large-scale analysis of proteins, is contributing greatly to our understanding of disease mechanisms. Proteomics st...
Classifying mild traumatic brain injuries with functional network analysis [0.03%]
基于功能网络分析的脑震荡损伤分类研究
F Anthony San Lucas,John Redell,Dash Pramod et al.
F Anthony San Lucas et al.
Background: Traumatic brain injury (TBI) represents a critical health problem of which timely diagnosis and treatment remain challenging. TBI is a result of an external force damaging brain tissue, accompanied by delayed ...
An experimental design framework for Markovian gene regulatory networks under stationary control policy [0.03%]
稳态控制策略下马尔可夫基因调控网络的实验设计框架
Roozbeh Dehghannasiri,Mohammad Shahrokh Esfahani,Edward R Dougherty
Roozbeh Dehghannasiri
Background: A fundamental problem for translational genomics is to find optimal therapies based on gene regulatory intervention. Dynamic intervention involves a control policy that optimally reduces a cost function based ...
The International Conference on Intelligent Biology and Medicine (ICIBM) 2018: systems biology on diverse data types [0.03%]
2018年国际智能生物学和医学会议（ICIBM）：多样型数据的系统生物学
Kai Wang,Xiaoming Liu,Yan Guo et al.
Kai Wang et al.
Between June 10-12, 2018, the International Conference on Intelligent Biology and Medicine (ICIBM 2018) was held in Los Angeles, California, USA. The conference included 11 scientific sessions, four tutorials, one poster session, four keyno...
Qualitative modelling of the interplay of inflammatory status and butyrate in the human gut: a hypotheses about robust bi-stability [0.03%]
肠道炎症状态与丁酸盐相互作用的定性建模：关于稳健双稳态的一个假说
Gunter Neumann,Rebecca Wall,Ignacio Rangel et al.
Gunter Neumann et al.
Background: Gut microbiota interacts with the human gut in multiple ways. Microbiota composition is altered in inflamed gut conditions. Likewise, certain microbial fermentation products as well as the lipopolysaccharides ...
Gabriela I Guzmán,Connor A Olson,Ying Hefner et al.
Gabriela I Guzmán et al.
Background: Essentiality assays are important tools commonly utilized for the discovery of gene functions. Growth/no growth screens of single gene knockout strain collections are also often utilized to test the predictive...
Co-expression of long non-coding RNAs and autism risk genes in the developing human brain [0.03%]
自闭症风险基因与长链非编码RNA在发育人脑中的共表达
Steven B Cogill,Anand K Srivastava,Mary Qu Yang et al.
Steven B Cogill et al.
Background: Autism Spectrum Disorder (ASD) is the umbrella term for a group of neurodevelopmental disorders convergent on behavioral phenotypes. While many genes have been implicated in the disorder, the predominant focus...
Dan Li,William Yang,Carolyn Arthur et al.
Dan Li et al.
Background: Adenocarcinoma in situ (AIS) is a pre-invasive lesion in the lung and a subtype of lung adenocarcinoma. The patients with AIS can be cured by resecting the lesion completely. In contrast, the patients with inv...
A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity [0.03%]
用于揭示糖尿病和肥胖的热点分析-关系发现表示模型
Guannan He,Yanchun Liang,Yan Chen et al.
Guannan He et al.
Background: Nowadays, because of the huge economic burden on society causing by obesity and diabetes, they turn into the most serious public health challenges in the world. To reveal the close and complex relationships be...