Contemporary perspective and practical application of glutamate dehydrogenase in nonclinical studies [0.03%]
谷氨酸脱氢酶非临床研究中的应用及考量
Ravindra C Kodihalli,Mehrdad Ameri,Kevin S Baker et al.
Ravindra C Kodihalli et al.
The use of biomarkers in nonclinical species has gained significant attention for improving predictive accuracy in toxicological studies and early disease detection. This article focuses on glutamate dehydrogenase (GLDH), a mitochondrial en...
Clinical and prognostic value of biomarkers in patients with non-obstructive coronary artery disease: a systematic review and meta-analysis [0.03%]
非梗阻性冠心病患者生物标志物的临床和预后价值：系统回顾和meta分析
Léa Berbach,Elie Fadel,Brian J Potter et al.
Léa Berbach et al.
Background: Cardiovascular disease (CVD) remains the leading cause of premature mortality worldwide. Among its manifestations, ischemia with non-obstructive coronary arteries (INOCA) and myocardial infarction with non-obs...
Hepatic steatosis/fibrosis related biomarkers in patients with metabolic dysfunction-associated steatotic liver disease [0.03%]
与代谢功能异常相关性肝病患者肝脂肪变性和肝纤维化相关的生物标志物研究
Zhi Peng,Zijin Wang,Juan Wang et al.
Zhi Peng et al.
Aims: To explore hepatic steatosis and fibrosis related biomarkers in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). Pati...
Serum neuregulin -1 (NRG-1) is a potential biomarker for early diagnosis and prediction in refractory schizophrenia [0.03%]
血清神经调节蛋白-1(NRG-1)可作为难治性精神分裂症早期诊断和预后评估的潜在生物标志物
Ming Shu,Qiuying Chen
Ming Shu
Aims: This study tends to identify serum biomarkers for early diagnosis of treatment-resistant schizophrenia (TRS) and prediction of clozapine treatment response, given the heterogeneity of schizophrenia and limitations o...
Diagnostic and prognostic value of inflammatory markers for patients with severe pneumonia: a meta-analysis [0.03%]
炎症标志物在重症肺炎诊断和预后中的价值：一项系统评价和meta分析
Meng Han,Can Zhang,Songhe Zhao et al.
Meng Han et al.
Aims: This meta-analysis evaluates the diagnostic and prognostic performance of severe pneumonia through a comprehensive meta-analysis. Patients and metho...
Prognostic value of the preoperative hemoglobin-to-RDW ratio in endometrial cancer: a retrospective cohort study [0.03%]
术前血红蛋白与红细胞分布宽度比率比在子宫内膜癌中的预后价值：一项回顾性队列研究
Tung-Ying Wu,Pei-Ru Lin,Chew-Teng Kor et al.
Tung-Ying Wu et al.
Aims: The hemoglobin-to-red cell distribution width ratio (Hb/RDW) is a prognostic biomarker in various malignancies. However, its prognostic value in endometrial cancer (EC) remains unclear. This study investigated the a...
A CT-based deep learning radiomics model for predicting HER2 expression and prognosis in non-muscle-invasive bladder cancer [0.03%]
基于CT的深度学习影像组学模型在非肌层浸润性膀胱癌HER2表达及预后预测中的应用研究
Tian Jin,Huanrui Liu,Senlin Li et al.
Tian Jin et al.
Objective: This study aimed to extract radiomics (Rad) and deep learning (DL) features from preoperative CT of patients with Non-Muscle Invasive Bladder Cancer (NMIBC) and develop models incorporating clinical characteris...
A CTCs-based recurrence model for non-metastatic renal cell carcinoma: integrating machine learning and SHAP interpretation [0.03%]
基于CTCs的非转移性肾细胞癌复发模型：结合机器学习和SHAP解释
Geng Tian,Fabrice Kayitare,Xiaoyong Chen et al.
Geng Tian et al.
Background: Postoperative recurrence remains a significant challenge in renal cell carcinoma (RCC). While circulating tumor cells (CTCs) have emerged as promising prognostic biomarkers, the predictive value of their subty...
Derived neutrophil-to-lymphocyte ratio as a predictor of no-reflow in ST-elevation myocardial infarction [0.03%]
衍生的中性粒细胞与淋巴细胞比率在预测ST段抬高心肌梗死患者无复流中的价值
Alperen Taş,Muhammet Salih Ateş,Çağatay Tunca
Alperen Taş
Aims: The no-reflow (NR) phenomenon is a serious complication of primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI), often reflecting distal embolization and microvascular obstr...
MiR-153-3p modulates osteogenic differentiation of posterior longitudinal ligament cells via targeting KLF5 [0.03%]
microRNA-153-3p通过靶向KLF5调节后纵韧带细胞成骨分化
Liqi Chen,Jie Huang
Liqi Chen
Background: The ossification of the posterior longitudinal ligament (OPLL) represents a disabling spinal condition. The specific function of miR-153-3p in the context of OPLL has not been elucidated. ...