Renal Tissue-Derived Exosomal miRNA-34a in Diabetic Nephropathy Induces Renal Tubular Cell Fibrosis by Promoting the Polarization of M1 Macrophages [0.03%]
糖尿病肾病中肾组织源外泌体miRNA-34a通过促进M1型巨噬细胞极化诱导肾小管上皮细胞纤维化
Shuai Zheng,Yi Zeng,Liqing Chu et al.
Shuai Zheng et al.
Background: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease, and the activation and infiltration of phagocytes are critical steps of DN. This study aimed to explore the mechanism of exosomes in ma...
Enhancement of Therapeutic Potential of Oncolytic Virus with Homologous Tumor Cell Membranes for Pancreatic Cancer [0.03%]
用于胰腺癌治疗的溶瘤病毒与同源肿瘤细胞膜共孵育后的疗效增强作用研究
Wei Chen,Hui Liu,Yue Chen et al.
Wei Chen et al.
Pancreatic cancer is a leading cause of cancer-related deaths worldwide. Conventional therapies often provide limited success, necessitating the need for novel therapeutic strategies. Oncolytic viruses (OVs) are a class of viruses that spec...
Application of an Antibacterial Coating Layer via Amine-Terminated Hyperbranched Zirconium-Polysiloxane for Stainless Steel Orthodontic Brackets [0.03%]
基于氨基端羟基树枝状锆-聚硅氧烷抗菌涂层的不锈钢托槽的应用研究
Yaxin Qu,Xinwei Lu,Tingting Zhu et al.
Yaxin Qu et al.
The massive growth of various microorganisms on the orthodontic bracket can form plaques and cause diseases. A novel amine-terminated hyperbranched zirconium-polysiloxane (HPZP) antimicrobial coating was developed for an orthodontic stainle...
Cancer Vaccines Designed Based the Nanoparticle and Tumor Cells for the Treatment of Tumors: A Perspective [0.03%]
基于纳米粒子和肿瘤细胞的癌症疫苗在肿瘤治疗中的应用：展望观点文章
Qing-Juan Wu,Wen-Liang Lv
Qing-Juan Wu
Cancer vaccines based on tumor cell components have shown promising results in animal and clinical studies. The vaccine system contains abundant tumor antigen components, which can activate the immune system by antigens. However, their effi...
Rasool Azmoonfar,Masoud Moslehi,Daryoush Shahbazi-Gahrouei
Rasool Azmoonfar
Materials and methods: This study followed the PRISMA reporting guidelines to present the results. A comprehensive search was performed on electronic databases such as PubMed, Scopus, Web of Sciences, and Science Direct. ...
Antibacterial Activity and Mechanisms of Action of Inorganic Nanoparticles against Foodborne Bacterial Pathogens: A Systematic Review [0.03%]
无机纳米颗粒抗菌活性及作用机制的系统性综述——针对食源性致病菌的研究
Abayeneh Girma,Birhanu Abera,Bawoke Mekuye et al.
Abayeneh Girma et al.
Foodborne disease outbreaks due to bacterial pathogens and their toxins have become a serious concern for global public health and security. Finding novel antibacterial agents with unique mechanisms of action against the current spoilage an...
Thermosensitive Micelles Gel to Deliver Quercetin Locally for Enhanced Antibreast Cancer Efficacy: An In Vitro Evaluation [0.03%]
用于局部递送芦丁的热致凝胶微型米粒的体内抗乳腺癌效果研究
Yanxue Sun,Yun Bai,Silu Liu et al.
Yanxue Sun et al.
Although quercetin is low cytotoxicity to normal human cells, quercetin is effective against the growth of some tumors. Given the poor blood stability in vivo, insolubility, low delivery efficiency, and poor medicinal properties of querceti...
Analysis of the association between glomerular filtration rate, proteinuria and metabolic syndrome in chronic kidney patients based on longitudinal data [0.03%]
基于纵向数据的慢性肾脏病患者肾小球滤过率、尿蛋白与代谢综合征关联性分析
Li Guo,Shanshan Guo,Youlan Gong et al.
Li Guo et al.
Chronic kidney disease (CKD) is a group of chronic diseases caused by kidney damage from multiple causes. Metabolic syndrome (MS) manifests as dysfunction of endothelial cells and chronic functional inflammatory states, and may be involved ...
Natural compound chaetocin induced DNA damage and apoptosis through reactive oxygen species-dependent pathways in A549 lung cancer cells and in vitro evaluations [0.03%]
天然化合物链孢霉素通过依赖活性氧的途径诱导A549肺癌细胞和体外评估中的DNA损伤和凋亡
Qi Zhang,Feng Ruan,Maonan Yang et al.
Qi Zhang et al.
There is an urgent need for potential pharmaceutics for lung cancer treatment due to the increased number of lung cancer deaths and the resistance of cancer cells to present therapeutics. The present work aims to discover the anticancer pot...
Synthesis and characterisation of a novel poly(2-hydroxyethylmethacrylate)-chitosan hydrogels loaded cerium oxide nanocomposites dressing on cutaneous wound healing on nursing care of chronic wound [0.03%]
用于护理慢性伤口的新型聚（2-羟乙基甲基丙烯酸酯）-壳聚糖载氧化铈纳米复合材料水凝胶的合成及表征和评价其对皮肤伤口愈合的影响研究
Jingna Luo,Weijun Liu,Qiaoling Xie et al.
Jingna Luo et al.
This study was designed to establish the composition of wound dressing based on poly(2-hydroxyethylmethacrylate)-chitosan (PHEM-CS) hydrogels-loaded cerium oxide nanoparticle (CeONPs) composites for cutaneous wound healing on nursing care o...