Instrumentation development, improvement, simplification, and miniaturization: The multifunctional plate source for use in mass spectrometry [0.03%]
仪器开发、改进和小型化：用于质谱的多功能平板源
Sarah Trimpin,Ellen Inutan,Hope Coffinberger et al.
Sarah Trimpin et al.
In remembrance of Prof. Dr Przybylski, we are presenting a vision towards his beloved mass spectrometry (MS) and its far-reaching promises outside of the academic laboratory. Sub-atmospheric pressure (AP) ionization MS is well positioned to...
Intramolecular interactions and the neutral loss of ammonia from collisionally activated, protonated ω-aminoalkyl-3-hydroxyfurazans [0.03%]
分子内作用力与ω-氨基烷基-3-羟基呋咱
J Stuart Grossert,Donatella Boschi,Marco L Lolli et al.
J Stuart Grossert et al.
Gas phase fragmentation reactions of monoprotonated 4-(3-aminopropyl)- and 4-(4-aminobutyl)-3-hydroxyfurazan were investigated to examine potential interactions between functional groups. The two heterocyclic alkyl amines were ionized by el...
Epitope characterization of proteins and aptamers with mass spectrometry [0.03%]
基于质谱的表位鉴定技术及其在蛋白质和适配体研究中的应用
Loredana Lupu,Wolfgang Kleinekofort,Nina Morgner
Loredana Lupu
The way in which professor Michael Przybylski has combined the spirit of research with entrepreneurship has set an example for any and all scientists. He has made significant achievements in the fields of mass spectrometry, biochemistry and...
Method for determination of elemental impurities in metronidazole benzoate using inductively coupled plasma mass spectrometry [0.03%]
用于苯甲酸甲硝唑中元素杂质测定的电感耦合等离子体质谱法
Maoxian Tian,Hui Zhang,Huajun Fan et al.
Maoxian Tian et al.
The elemental impurities in pharmaceutical products have aroused widespread concern among respective supervising authorities and official pharmacopoeias since they are harmful and have no therapeutic effects. Metronidazole benzoate is used ...
N V Konenkov
N V Konenkov
In the development of commercial quadrupole mass spectrometers, there is an interest in improving the performance characteristics such as transmission, resolution, and mass range. In particular, parametric and dipolar resonance excitation o...
Coordination and fragmentation chemistry of CyMe4-BTPhen complexes with lanthanides and actinides: A combined investigation by ESI-MS and DFT calculations [0.03%]
CyMe4-BTPhen类稀土及锕系元素配合物的协同与碎片化学：ESI-质谱和DFT计算联合研究
Qiqi Zhang,Yang Liu,Shuping Tan et al.
Qiqi Zhang et al.
To further understand the complexation and fragmentation during the extraction process, the formation of 2,9-bis(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-12,4-benzotriazin-3-yl)-1,10-phenanthroline (CyMe4-BTPhen) complexes with lanthanides (L...
Toward a MALDI in-source decay (ISD) method for top-down analysis of protein footprinting [0.03%]
基于MALDI源内裂解的蛋白质足迹学(top-down分析)方法的发展
Ruidong Jiang,Don L Rempel,Michael L Gross
Ruidong Jiang
Irreversible protein footprinting is a mass spectrometry-based approach in which solvent-accessible sites of a protein are modified to assess high-order protein structure. Structural insights can be gained by determining the position and ex...
Top-down mass spectrometry for characterizing the low molecular weight proteome of canine osteosarcoma cell phenotypes [0.03%]
基于顶部质量数的质谱分析法研究犬类骨肉瘤细胞表型的低分子量蛋白质组学特征
Liping Yang,Stanislau Stanisheuski,Zifeng Song et al.
Liping Yang et al.
Osteosarcoma (OS) is the most common primary malignant tumor of bone, which occupying about 20% of all bone cancers. To increase understanding of the biology of OS, we developed and evaluated a top-down mass spectrometry approach to detect,...
Epitope identification of a Lys63 linkage ubiquitin antibody by mass spectrometric epitope excision and extraction approaches [0.03%]
基于肽段切除和抽提的质谱表位鉴定技术研究一种K63泛素链特异性抗体的结合表位
Ji Eun Jung,Vanessa Cárdenas,Brîndușa Alina Petre
Ji Eun Jung
Ubiquitin, a conserved protein in eukaryotic cells, exists as a monomer or polyubiquitin chains known as isopeptide-linked polymers. These chains are attached to a substrate or other ubiquitin molecules through a covalent bond between the ...
Lyso-phosphatidylethanol detected by LC-MS/MS as a potential new marker for alcohol consumption [0.03%]
通过LC-MS/MS检测到的溶血磷脂酰乙醇作为饮酒的新潜在标志物
Matthias Bantle,Lanya van Tieghem,Wolfgang Weinmann et al.
Matthias Bantle et al.
Alcohol biomarkers are able to reflect the degree of recent or long-term alcohol consumption, covering different windows of detection. Phosphatidylethanols (PEths) are an emerging group of direct alcohol biomarkers that are widely applied i...